Search Results - "Ryan, Katie R"

Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma by Mikulasova, Aneta, Ashby, Cody, Tytarenko, Ruslana G, Qu, Pingping, Rosenthal, Adam, Dent, Judith A, Ryan, Katie R, Bauer, Michael A, Wardell, Christopher P, Hoering, Antje, Mavrommatis, Konstantinos, Trotter, Matthew, Deshpande, Shayu, Yaccoby, Shmuel, Tian, Erming, Keats, Jonathan, Auclair, Daniel, Jackson, Graham H, Davies, Faith E, Thakurta, Anjan, Morgan, Gareth J, Walker, Brian A

“…is a widely acting transcription factor and its deregulation is a crucial event in many human cancers. is important biologically and clinically in multiple…”
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Differential regulation of adhesion complex turnover by ROCK1 and ROCK2 by Lock, Frances E, Ryan, Katie R, Poulter, Natalie S, Parsons, Maddy, Hotchin, Neil A

“…ROCK1 and ROCK2 are serine/threonine kinases that function downstream of the small GTP-binding protein RhoA. Rho signalling via ROCK regulates a number of…”
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Activation of RHO-1 in cholinergic motor neurons competes with dopamine signalling to control locomotion by Essmann, Clara L, Ryan, Katie R, Elmi, Muna, Bryon-Dodd, Kimberley, Porter, Andrew, Vaughan, Andrew, McMullan, Rachel, Nurrish, Stephen

“…The small GTPase RhoA plays a crucial role in the regulation of neuronal signalling to generate behaviour. In the developing nervous system RhoA is known to…”
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Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer by Clarke, Kim, Daubon, Thomas, Turan, Nil, Soulet, Fabienne, Mohd Zahari, Maihafizah, Ryan, Katie R, Durant, Sarah, He, Shan, Herbert, John, Ankers, John, Heath, John K, Bjerkvig, Rolf, Bicknell, Roy, Hotchin, Neil A, Bikfalvi, Andreas, Falciani, Francesco

“…Gliomas are a highly heterogeneous group of brain tumours that are refractory to treatment, highly invasive and pro-angiogenic. Glioblastoma patients have an…”
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Targeting both BET and CBP/EP300 proteins with the novel dual inhibitors NEO2734 and NEO1132 leads to anti‐tumor activity in multiple myeloma by Ryan, Katie R., Giles, Francis, Morgan, Gareth J.

“…Objectives Two promising epigenetic therapeutic targets have emerged for the treatment of hematologic malignancies, BET and CBP/EP300 proteins. Several studies…”
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Cellular traction forces increase during consecutive mechanical stretching following traction force attenuation by Akira TSUKAMOTO, Katie R. RYAN, Yusuke MITSUOKA, Katsuko S. FURUKAWA, Takashi USHIDA

“…Adherent cells generate traction forces, which are generated by and transmitted along the actin cytoskeleton to the underlying external substrate via focal…”
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Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3 by Ryan, Katie R, Lock, Frances E, Heath, John K, Hotchin, Neil A

“…The human epidermis is a self-renewing, stratified epithelial tissue that provides the protective function of the skin. The principal cell type within the…”
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Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer: e1005325 by Clarke, Kim, Daubon, Thomas, Turan, Nil, Soulet, Fabienne, Zahari, Maihafizah Mohd, Ryan, Katie R, Durant, Sarah, He, Shan, Herbert, John, Ankers, John, Heath, John K, Bjerkvig, Rolf, Bicknell, Roy, Hotchin, Neil A, Bikfalvi, Andreas, Falciani, Francesco

“…Gliomas are a highly heterogeneous group of brain tumours that are refractory to treatment, highly invasive and pro-angiogenic. Glioblastoma patients have an…”
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Hematopoietic stem cell-derived adipocytes and fibroblastsin the tumor microenvironment by Ying Xiong Lindsay T McDonald Dayvia L Russell Ryan R Kelly Katie R Wilson Meenal Mehrotra Adam C Soloff Amanda C LaRue

“…The tumor microenvironment （TME） is complex andconstantly evolving. This is due, in part, to the crosstalkbetween tumor cells and the multiple cell types…”
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