Search Results - "Ryan, Jackson W."

Sex-related differences in the skeletal phenotype of aged vitamin D receptor global knockout mice by Ryan, Jackson W., Starczak, Yolandi, Tsangari, Helen, Sawyer, Rebecca K., Davey, Rachel A., Atkins, Gerald J., Morris, Howard A., Anderson, Paul H.

“…•Adult male Vdr−/− mice exhibit bone loss despite being fed the rescue diet.•Female Vdr−/− mice exhibit vertebral bone loss and yet increased femoral bone…”
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Novel targets of vitamin D activity in bone: action of the vitamin D receptor in osteoblasts, osteocytes and osteoclasts by Ryan, Jackson W, Reinke, Daniel, Kogawa, Masakazu, Turner, Andrew G, Atkins, Gerald J, Anderson, Paul H, Morris, Howard A

“…The active form of vitamin D, 1,25-dihydroxyvitamin D3, carries out its diverse range of biological activities by binding to the nuclear vitamin D receptor,…”
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Vitamin D activities and metabolic bone disease by Ryan, Jackson W., Anderson, Paul H., Turner, Andrew G., Morris, Howard A.

“…Vitamin D activity requires an adequate vitamin D status as indicated by the serum level of 25-hydroxyvitamin D and appropriate expression of genes coding for…”
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Absence of vitamin D receptor in mature osteoclasts results in altered osteoclastic activity and bone loss by Starczak, Yolandi, Reinke, Daniel C., Barratt, Kate R., Ryan, Jackson W., Russell, Patricia K., Clarke, Michele V., St-Arnaud, René, Morris, Howard A., Davey, Rachel A., Atkins, Gerald J., Anderson, Paul H.

“…•The deletion of vitamin D receptor in osteoclasts results in femoral bone loss.•Osteoclast-specific VDRKO mice exhibit a marked reduction in thin trabeculae…”
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Pleiotropic Activities of Vitamin D Receptors - Adequate Activation for Multiple Health Outcomes by Ryan, Jackson W, Anderson, Paul H, Morris, Howard A

“…The vitamin D receptor (VDR), a nuclear transcription factor, elicits physiological regulation of gene transcription following binding of its ligand,…”
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