Search Results - "Ryan, J J"
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The Emergence of Manganese-Based Carbonyl Hydrosilylation Catalysts
Published in Accounts of chemical research (21-11-2017)“…Conspectus In recent years, interest in homogeneous manganese catalyst development has intensified because of the earth-abundant and nontoxic nature of this…”
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Trauma, PTSD, and the Developing Brain
Published in Current psychiatry reports (01-10-2017)“…Purpose of Review PTSD in youth is common and debilitating. In contrast to adult PTSD, relatively little is known about the neurobiology of pediatric PTSD, nor…”
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HD 209458b in new light: evidence of nitrogen chemistry, patchy clouds and sub-solar water
Published in Monthly notices of the Royal Astronomical Society (01-08-2017)“…Abstract Interpretations of exoplanetary transmission spectra have been undermined by apparent obscuration due to clouds/hazes. Debate rages on whether weak…”
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Immune-related toxicities of checkpoint inhibitors: mechanisms and mitigation strategies
Published in Nature reviews. Drug discovery (01-07-2022)“…The immune-related adverse events associated with treatment with immune checkpoint inhibitors result in significant morbidity for patients as well as…”
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An Update on Mitochondrial Reactive Oxygen Species Production
Published in Antioxidants (02-06-2020)“…Mitochondria are quantifiably the most important sources of superoxide (O2●−) and hydrogen peroxide (H2O2) in mammalian cells. The overproduction of these…”
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Mitochondrial Antioxidants and the Maintenance of Cellular Hydrogen Peroxide Levels
Published in Oxidative medicine and cellular longevity (01-01-2018)“…For over 40 years, mitochondrial reactive oxygen species (ROS) production and balance has been studied in the context of oxidative distress and tissue damage…”
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ADAPTIVE PIECEWISE POLYNOMIAL ESTIMATION VIA TREND FILTERING
Published in The Annals of statistics (01-02-2014)“…We study trend filtering, a recently proposed tool of Kim et al. [SIAM Rev. 51 (2009) 339-360] for nonparametric regression. The trend filtering estimate is…”
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Reading, writing and erasing mRNA methylation
Published in Nature reviews. Molecular cell biology (01-10-2019)“…RNA methylation to form N 6 -methyladenosine (m 6 A) in mRNA accounts for the most abundant mRNA internal modification and has emerged as a widespread…”
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Distribution-Free Predictive Inference for Regression
Published in Journal of the American Statistical Association (03-07-2018)“…We develop a general framework for distribution-free predictive inference in regression, using conformal inference. The proposed methodology allows for the…”
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One Percent Determination of the Primordial Deuterium Abundance
Published in The Astrophysical journal (10-03-2018)“…Abstract We report a reanalysis of a near-pristine absorption system, located at a redshift toward the quasar Q1243+307, based on the combination of archival…”
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Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
Published in Cancer cell (13-10-2014)“…Tumor suppressors with widespread impact on carcinogenesis control broad spectra of oncogenic pathways. Protein degradation is an emerging mechanism by which…”
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Protein S-glutathionylation reactions as a global inhibitor of cell metabolism for the desensitization of hydrogen peroxide signals
Published in Redox biology (01-05-2020)“…The pathogenesis of many human diseases has been attributed to the over production of reactive oxygen species (ROS), particularly superoxide (O2●-) and…”
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Surprises in high-dimensional ridgeless least squares interpolation
Published in The Annals of statistics (01-04-2022)“…Interpolators-estimators that achieve zero training error-have attracted growing attention in machine learning, mainly because state-of-the art neural networks…”
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Teaching the fundamentals of electron transfer reactions in mitochondria and the production and detection of reactive oxygen species
Published in Redox biology (01-04-2015)“…Mitochondria fulfill a number of biological functions which inherently depend on ATP and O2(-•)/H2O2 production. Both ATP and O2(-•)/H2O2 are generated by…”
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Peptide-Based Vaccines: Current Progress and Future Challenges
Published in Chemical reviews (25-03-2020)“…Vaccines have had a profound impact on the management and prevention of infectious disease. In addition, the development of vaccines against chronic diseases…”
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The survival of multiphase dusty clouds in hot winds
Published in Monthly notices of the Royal Astronomical Society (01-02-2022)“…ABSTRACT Much progress has been made recently in the acceleration of ∼104 K clouds to explain absorption line measurements of the circumgalactic medium and the…”
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Kinematics and host-galaxy properties suggest a nuclear origin for calcium-rich supernova progenitors
Published in Monthly notices of the Royal Astronomical Society (21-09-2015)“…Calcium-rich supernovae (Ca-rich SNe) are peculiar low-luminosity SNe Ib with relatively strong Ca spectral lines at ∼2 months after peak brightness. This…”
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Engram cells retain memory under retrograde amnesia
Published in Science (American Association for the Advancement of Science) (29-05-2015)“…Memory consolidation is the process by which a newly formed and unstable memory transforms into a stable long-term memory. It is unknown whether the process of…”
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Lysine Acetylation Goes Global: From Epigenetics to Metabolism and Therapeutics
Published in Chemical reviews (14-02-2018)“…Post-translational acetylation of lysine residues has emerged as a key regulatory mechanism in all eukaryotic organisms. Originally discovered in 1963 as a…”
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Sinks and sources: Assessing microplastic abundance in river sediment and deposit feeders in an Austral temperate urban river system
Published in The Science of the total environment (15-01-2018)“…•Microplastics abundance in sediment and chironomid larvae varied from wet to dry periods.•There was a relationship between sediment and chironomid…”
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