Search Results - "Ryan, Catherine L."

Ischemic lesions localized to the medial prefrontal cortex produce selective deficits in measures of executive function in rats by Déziel, Robert A., Ryan, Catherine L., Tasker, R. Andrew

“…•There are few pre-clinical models for higher-order cognitive dysfunction following stroke.•Microinjections of endothelin-1 result in ischemic lesions in the…”
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Hippocampal mossy fiber sprouting and elevated trkB receptor expression following systemic administration of low dose domoic acid during neonatal development by Bernard, Paul B., MacDonald, Debra S., Gill, Daphne A., Ryan, Catherine L., Tasker, R. Andrew

“…We have previously reported that serial systemic injections of low‐dose (subconvulsive) domoic acid (DOM) during early postnatal development produces changes…”
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Effectiveness of PSD95 Inhibitors in Permanent and Transient Focal Ischemia in the Rat by SUN, Hong-Shuo, DOUCETTE, Tracy A, SALTER, Michael W, YU TIAN WANG, TASKER, R. Andrew, TYMIANSKI, Michael, YITAO LIU, YUAN FANG, TEVES, Lucy, AARTS, Michelle, RYAN, Catherine L, BERNARD, Paul B, LAU, Anthony, FORDER, Joan P

“…Postsynaptic density-95 inhibitors reduce ischemic brain damage without inhibiting excitatory neurotransmission, circumventing the negative consequences of…”
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Alterations to prepulse inhibition magnitude and latency in adult rats following neonatal treatment with domoic acid and social isolation rearing by Marriott, Amber L., Tasker, R. Andrew, Ryan, Catherine L., Doucette, Tracy A.

“…•Adults rats were assessed following neonatal DOM treatment and/or isolation rearing.•Social isolation lowered PPI amplitude in male rats.•DOM treatment made…”
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Neonatal domoic acid abolishes latent inhibition in male but not female rats and has differential interactions with social isolation by Marriott, Amber L., Tasker, R Andrew, Ryan, Catherine L., Doucette, Tracy A.

“…•Latent inhibition was measured in male and female rats following neonatal drug and/or isolation housing.•Neonatal injections of low dose domoic acid abolished…”
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Neonatal domoic acid treatment produces alterations to prepulse inhibition and latent inhibition in adult rats by Marriott, Amber L., Ryan, Catherine L., Doucette, Tracy A.

“…Schizophrenia is a complex and severe mental disorder characterized by positive, negative and cognitive symptoms. Characteristic behavioral alterations…”
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Persistent changes in learning and memory in rats following neonatal treatment with domoic acid by Adams, Amber L, Doucette, Tracy A, James, Rebecca, Ryan, Catherine L

“…Abstract The present study examined the effects of neonatal exposure to serial low dose injections of the glutamate agonist, domoic acid (DOM), on learning and…”
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Altered responses to novelty and drug reinforcement in adult rats treated neonatally with domoic acid by Burt, Melissa A, Ryan, Catherine L, Doucette, Tracy A

“…Abstract Activity in the mesocorticolimbic dopamine system is linked to responses to novelty, reward, and drug-seeking behaviours. Glutamate signaling, through…”
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Effects of low dose neonatal domoic acid administration on behavioural and physiological response to mild stress in adult rats by Perry, Melissa A, Ryan, Catherine L, Tasker, R. Andrew

“…Abstract Changes in glutamatergic signalling during neonatal development are known to result in long-lasting changes in brain function. Previous work in our…”
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Altered social interaction in adult rats following neonatal treatment with domoic acid by Ryan, Catherine L, Robbins, Mark A, Smith, Meghan T, Gallant, Ian C, Adams-Marriott, Amber L, Doucette, Tracy A

“…Abstract Schizophrenia is a debilitating neurological disorder characterized by positive, negative, cognitive and/or emotional symptoms. Decreased social…”
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Effects of estrous stage and time of day on prepulse inhibition in female rats by Adams, Amber L., Hudson, Amanda, Ryan, Catherine L., Doucette, Tracy A.

“…Prepulse inhibition (PPI) of the acoustic startle response is a measure of sensory motor gating, and is affected in various neuropsychiatric disorders…”
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An improved post-operative care protocol allows detection of long-term functional deficits following MCAo surgery in rats by Ryan, Catherine L., Doucette, Tracy A., Gill, Daphne A., Langdon, Kris D., Liu, Yitao, Perry, Melissa A., Tasker, R. Andrew

“…Developing new therapeutants for stroke requires animal models in which typical stroke outcomes can be detected. In rats, temporary occlusion of the middle…”
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Low doses of non-NMDA glutamate receptor agonists alter neurobehavioural development in the rat by Doucette, Tracy A., Bernard, Paul B., Yuill, P.Corrinne, Tasker, R.Andrew, Ryan, Catherine L.

“…While it is known that glutamate is critical to CNS development and function, less is known about the role of kainate receptors, a subclass of ionotropic…”
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Use of osmotic minipumps for sustained drug delivery in rat pups: effects on physical and neurobehavioural development by Doucette, Tracy A, Ryan, Catherine L, Tasker, R.Andrew

“…Osmotic minipumps are often used as an alternative to repetitive injections for prolonged drug delivery in adult rats. The appropriateness of using this…”
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Prenatal exposure to three antiadrenergic antihypertensive drugs: Effects on neurobehavioral development and on the neural and behavioral consequences of enriched environments by Ryan, Catherine L

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Prenatal exposure to antiadrenergic antihypertensive drugs: effects on neurobehavioral development and the behavioral consequences of enriched rearing by Ryan, C L, Pappas, B A

“…One of the beta blockers propranolol (5 or 20 mg/kg) or atenolol (5 or 20 mg/kg) or the alpha-2 agonist clonidine (20 or 100 micrograms/kg) was administered in…”
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A behavioral and electrocorticographic comparison of diazepam and pentylenetetrazol in rat pups by Smythe, J W, Ryan, C L, Pappas, B A

“…This experiment assessed the possibility suggested by previous research that benzodiazepines cause convulsions in infant rats. Seven-day-old Wistar rats were…”
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Regulation of [3H]imipramine binding sites in rat brain regions: effect of neonatal 5,7-dihydroxytryptamine treatment by Hrdina, P D, Pappas, B A, Bialik, R J, Ryan, C L

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חקר ההשפעה של תרופות ושל שימוש במשוב ממוחשב על ביצוע משימה אצל ילדי AD/HD by ברט, קאתי, רייאן, קתרין, Burt, Kathy L., Ryan, Catherine L.

“…המחקר המתואר במאמר זה חקר את הביצוע של ילדים בעלי הפרעת קשב/היפראקטיביות (Attention-Deficit/Hyperactivity Disorder), מהסוג המשולב (AD/HD) במשימות ממוחשבות…”
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