Search Results - "Ruzdijić, Sabera"
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1
Effects of Different Dietary Protocols on General Activity and Frailty of Male Wistar Rats During Aging
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (09-07-2018)“…Dietary restriction (DR) is an important experimental paradigm for lifespan and healthspan extension, but its specific contribution regarding the type, onset,…”
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2
Potential mechanism of cell death in the developing rat brain induced by propofol anesthesia
Published in International journal of developmental neuroscience (01-05-2009)“…Commonly used general anesthetics can have adverse effects on the developing brain by triggering apoptotic neurodegeneration, as has been documented in the…”
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3
The influence of propofol anesthesia exposure on nonaversive memory retrieval and expression of molecules involved in memory process in the dorsal hippocampus in peripubertal rats
Published in Pediatric anesthesia (01-06-2018)“…Summary Background The effects of anesthetic drugs on postoperative cognitive function in children are not well defined and have not been experimentally…”
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4
Isolation and Biological Evaluation of Jatrophane Diterpenoids from Euphorbia dendroides
Published in Journal of natural products (Washington, D.C.) (22-07-2011)“…From the Montenegrin spurge Euphorbia dendroides, seven new diterpenoids [jatrophanes (1–6) and a tigliane (7)] were isolated and their structures elucidated…”
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5
Caloric restriction suppresses microglial activation and prevents neuroapoptosis following cortical injury in rats
Published in PloS one (15-05-2012)“…Traumatic brain injury (TBI) is a widespread cause of death and a major source of adult disability. Subsequent pathological events occurring in the brain after…”
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6
Propofol-induced changes in neurotrophic signaling in the developing nervous system in vivo
Published in PloS one (04-04-2012)“…Several studies have revealed a role for neurotrophins in anesthesia-induced neurotoxicity in the developing brain. In this study we monitored the spatial and…”
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7
The Fas Ligand/Fas Death Receptor Pathways Contribute to Propofol-Induced Apoptosis and Neuroinflammation in the Brain of Neonatal Rats
Published in Neurotoxicity research (01-10-2016)“…A number of experimental studies have reported that exposure to common, clinically used anesthetics induce extensive neuroapoptosis and cognitive impairment…”
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8
BDNF transcripts, proBDNF and proNGF, in the cortex and hippocampus throughout the life span of the rat
Published in AGE (01-12-2013)“…Neurotrophins are established molecular mediators of neuronal plasticity in the adult brain. We analyzed the impact of aging on brain-derived neurotrophic…”
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Brain molecular changes and behavioral alterations induced by propofol anesthesia exposure in peripubertal rats
Published in Pediatric anesthesia (01-09-2017)“…Background Propofol is commonly used in modern anesthesiology. Some findings suggest that it is highly addictive. Aim In this study it was examined whether…”
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10
Neonatal Propofol Anesthesia Changes Expression of Synaptic Plasticity Proteins and Increases Stereotypic and Anxyolitic Behavior in Adult Rats
Published in Neurotoxicity research (01-08-2017)“…Propofol is a general anesthetic commonly used in pediatric clinical practices. Experimental findings demonstrate that anesthetics induce widespread apoptosis…”
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11
Identification of novel genetic alterations in samples of malignant glioma patients
Published in PloS one (16-12-2013)“…Glioblastoma is the most frequent and malignant human brain tumor. High level of genomic instability detected in glioma cells implies that numerous genetic…”
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12
The role of paclitaxel in the development and treatment of multidrug resistant cancer cell lines
Published in Biomedicine & pharmacotherapy (01-08-2011)“…Abstract Paclitaxel (PTX) is used for treatment of wide range of solid tumors, but its efficacy is often limited by appearance of multidrug resistance (MDR)…”
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13
Propofol anesthesia induces proapoptotic tumor necrosis factor-α and pro-nerve growth factor signaling and prosurvival Akt and XIAP expression in neonatal rat brain
Published in Journal of neuroscience research (01-10-2014)“…Previously we observed that prolonged exposure to propofol anesthesia causes caspase‐3‐ and calpain‐mediated neuronal death in the developing brain. The…”
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14
Purine nucleoside analog--sulfinosine modulates diverse mechanisms of cancer progression in multi-drug resistant cancer cell lines
Published in PloS one (11-01-2013)“…Achieving an effective treatment of cancer is difficult, particularly when resistance to conventional chemotherapy is developed. P-glycoprotein (P-gp) activity…”
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15
Induction of TNF-α signaling cascade in neonatal rat brain during propofol anesthesia
Published in International journal of developmental neuroscience (01-08-2015)“…•Propofol in PND14 rats simultaneously activates pro- and anti-apoptotic signaling.•TNF-α signaling exhibit brain region-specific difference after propofol…”
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16
Aging Induces Tissue-Specific Changes in Cholesterol Metabolism in Rat Brain and Liver
Published in Lipids (01-11-2013)“…Disturbance of cholesterol homeostasis in the brain is coupled to age-related brain dysfunction. In the present work, we studied the relationship between aging…”
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17
The elimination of P-glycoprotein over-expressing cancer cells by antimicrobial cationic peptide NK-2: The unique way of multi-drug resistance modulation
Published in Experimental cell research (15-04-2013)“…Most chemotherapeutics harm normal cells causing severe side effects and induce the development of resistance in cancer cells. Antimicrobial peptides (AMPs),…”
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18
Molecular and cytogenetic changes in multi-drug resistant cancer cells and their influence on new compounds testing
Published in Cancer chemotherapy and pharmacology (01-09-2013)“…Purpose Multi-drug resistance (MDR) is a major obstacle to successful cancer treatment. Therefore, in vitro models are necessary for the investigation of the…”
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Neonatal propofol anesthesia modifies activity-dependent processes and induces transient hyperlocomotor response to d-amphetamine during adolescence in rats
Published in International journal of developmental neuroscience (01-12-2015)“…•Propofol affected activity-regulated events in the frontal cortex and thalamus of P7 rats.•Propofol changed BDNF and c-Fos expression in time- and…”
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20
Changes in markers of neuronal and glial plasticity after cortical injury induced by food restriction
Published in Experimental neurology (01-11-2009)“…The regenerative capacity of the adult central nervous system is limited. We investigated whether short-term food restriction (FR; 50% of the daily food intake…”
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