Search Results - "Ruus, P."
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Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin
Published in Diabetes, obesity & metabolism (01-07-2013)“…ABSTRACT Aim Assess the pharmacodynamics of lixisenatide once daily (QD) versus liraglutide QD in type 2 diabetes insufficiently controlled on metformin…”
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Oral administration of rac-α-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo-controlled pilot trial
Published in Free radical biology & medicine (01-08-1999)“…α-lipoic acid (ALA), a naturally occuring compound and a radical scavenger was shown to enhance glucose transport and utilization in different experimental and…”
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Effects of age and sex on the disposition of retigabine
Published in Clinical pharmacology and therapeutics (01-01-2003)“…Background The novel antiepileptic drug retigabine is the first selective M‐current potassium channel opener for KCNQ2/3 and KCNQ3/5 channels. Retigabine…”
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PO13 Caractéristiques pharmacodynamiques du lixisénatide en une prise quotidienne vs le liraglutide chez des patients ayant un diabète de type 2 (DT2) non équilibré sous metformine
Published in Diabetes & metabolism (01-03-2012)“…Objectif Cette étude randomisée, ouverte, avec administration répétée pendant 4 semaines, a comparé la pharmacodynamie du lixisénatide (20 µg par jour) vs le…”
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Enantioselective pharmacokinetics and bioavailability of different racemic α-lipoic acid formulations in healthy volunteers
Published in European journal of pharmaceutical sciences (01-05-1996)“…The pharmacokinetics and the absolute bioavailability of the enantiomers of α-lipoic acid (α-LA) from different dosage forms have been studied for the first…”
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Plasma Kinetics, Metabolism, and Urinary Excretion of Alpha-Lipoic Acid following Oral Administration in Healthy Volunteers
Published in Journal of clinical pharmacology (01-11-2003)“…R(+)‐alpha‐lipoic acid is a natural occurring compound that acts as an essential cofactor for certain dehydrogenase complexes. The redox couple alpha‐lipoic…”
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Pharmacokinetics of naftopidil, a novel anti-hypertensive drug, in patients with hepatic dysfunction
Published in Postgraduate medical journal (01-05-1994)“…The pharmacokinetics of naftopidil, a novel alpha-1 adrenoceptor-blocking antihypertensive, were investigated in ten patients (9M/1F) with hepatic dysfunction…”
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Pharmacokinetics of Alpha-Lipoic Acid in Subjects With Severe Kidney Damage and End-Stage Renal Disease
Published in Journal of clinical pharmacology (01-03-2005)“…In an open‐label, parallel‐group study involving 16 patients (8 with severely reduced renal function, 8 with end‐stage renal disease needing hemodialysis), the…”
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Retigabine N-Glucuronidation and Its Potential Role in Enterohepatic Circulation
Published in Drug metabolism and disposition (01-05-1999)“…The metabolism of retigabine in humans and dogs is dominated by N -glucuronidation ( McNeilly et al., 1997 ), whereas in rats, a multitude of metabolites of…”
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Gastric emptying in patients with insulin dependent diabetes mellitus and bioavailability of thioctic acid-enantiomers
Published in European journal of pharmaceutical sciences (1998)“…The objective of this study was to determine the impact of prolonged gastric emptying in patients with insulin dependent diabetes mellitus (IDDM) on the…”
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Time factors in endoscopic studies. A survey in West Germany
Published in Zeitschrift für Gastroenterologie (01-01-1990)“…In order to obtain representative data for the orientation of personal requirements in endoscopic units, 650 hospitals in the FRG were asked to have an exact…”
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Tolerability and in vivo performance of a novel freon-free metered dose inhaler for a fixed combinational product of reproterol and disodium cromoglycate
Published in Arzneimittel-Forschung (01-06-1998)“…The present study was conducted to describe and compare the in vivo performance (systemic exposure), clinical and laboratory safety of a fixed combinational…”
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Temporal aspects of endoscopic methods
Published in Verhandlungen der Deutschen Gesellschaft für Innere Medizin (1988)Get more information
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