Search Results - "Ruud, T. M."

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    Risk factors for QTc interval prolongation by Heemskerk, Charlotte P. M., Pereboom, Marieke, van Stralen, Karlijn, Berger, Florine A., van den Bemt, Patricia M. L. A., Kuijper, Aaf F. M., van der Hoeven, Ruud T. M., Mantel-Teeuwisse, Aukje K., Becker, Matthijs L.

    Published in European journal of clinical pharmacology (01-02-2018)
    “…Purpose Prolongation of the QTc interval may result in Torsade de Pointes, a ventricular arrhythmia. Numerous risk factors for QTc interval prolongation have…”
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    Journal Article
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    The effect of medication related clinical decision support at the time of physician order entry by Becker, Matthijs L., Baypinar, Fatih, Pereboom, Marieke, Lilih, Soufiane, van der Hoeven, Ruud T. M., Giezen, Thijs J., Kingma, Hylke Jan

    Published in International journal of clinical pharmacy (01-02-2021)
    “…Background In advanced clinical decision support systems, patient characteristics and laboratory values are included in the algorithms that generate alerts…”
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    Journal Article
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    Antibody arrays for high-throughput screening of antibody-antigen interactions by de Wildt, Ruud M. T, Tomlinson, Ian M, Mundy, Chris R, Gorick, Barbara D

    Published in Nature biotechnology (01-09-2000)
    “…We have developed a novel technique for high-throughput screening of recombinant antibodies, based on the creation of antibody arrays. Our method uses robotic…”
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    Journal Article
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    Development of a risk model for predicting QTc interval prolongation in patients using QTc-prolonging drugs by Bindraban, Anita N., Rolvink, José, Berger, Florine A., van den Bemt, Patricia M. L. A., Kuijper, Aaf F. M., van der Hoeven, Ruud T. M., Mantel-Teeuwisse, Aukje K., Becker, Matthijs L.

    Published in International journal of clinical pharmacy (01-10-2018)
    “…Background Numerous drugs prolong the QTc interval on the ECG and potentially increase the risk of cardiac arrhythmia. This risk is clinically relevant in…”
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    Journal Article
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    Physicians’ Compliance with a Clinical Decision Support System Alerting during the Prescribing Process by Baypinar, Fatih, Kingma, Hylke Jan, van der Hoeven, Ruud T. M., Becker, Matthijs L.

    Published in Journal of medical systems (01-06-2017)
    “…Clinical decision support systems have been shown to improve practitioner performance. Most systems designed to prevent medication errors generate lists with…”
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    Journal Article
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    A clinical decision support system to improve adequate dosing of gentamicin and vancomycin by Pereboom, Marieke, Mulder, Inge J., Verweij, Sjoerd L., van der Hoeven, Ruud T.M., Becker, Matthijs L.

    “…Gentamicin and vancomycin meet the criteria for measuring plasma concentrations during therapy. However, compliance with the accompanying guidelines remains…”
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    Journal Article
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    Isolation of Receptor-Ligand Pairs by Capture of Long-Lived Multivalent Interaction Complexes by Ruud M. T. de Wildt, Tomlinson, Ian M., Ong, Jennifer L., Holliger, Philipp

    “…We have combined phage display and array screening for the rapid isolation of pairs of interacting polypeptides. Our strategy, named SAC (selection by avidity…”
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    Journal Article
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    Improving the effectiveness of drug safety alerts to increase adherence to the guideline for gastrointestinal prophylaxis by Lilih, Soufiane, Pereboom, Marieke, van der Hoeven, Ruud T.M, Mantel-Teeuwisse, Aukje K, Becker, Matthijs L

    “…Highlights • We implemented a clinical decision support system for gastrointestinal prophylaxis. • Prescriptions for gastrointestinal prophylaxis increased…”
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    Journal Article
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    Creation of the large and highly functional synthetic repertoire of human VH and Vκ domain antibodies by Ignatovich, Olga, Jespers, Laurent, Tomlinson, Ian M, de Wildt, Ruud M T

    “…This protocol describes a method for creation of a highly diverse and functional synthetic phage-displayed repertoire of fully human domain antibodies (dAbs)…”
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    Journal Article
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    Post-Transcriptional Control of Class I MHC mRNA Expression in Adenovirus 12-Transformed Cells by Ruud T. M. J. Vaessen, Houweling, Ada, Van Der Eb, Alex J.

    “…Expression of the class I transplantation antigens of the major histocompatibility complex (MHC) is suppressed in cells transformed by the oncogenic human…”
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    Journal Article
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    Comparable heavy and light chain pairings in normal and systemic lupus erythematosus IgG+ B cells by de Wildt, Ruud M. T., Tomlinson, Ian M., van Venrooij, Walther J., Winter, Greg, Hoet, René M. A.

    Published in European journal of immunology (01-01-2000)
    “…Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the presence of high immunoglobulin serum titers, but the mechanism by…”
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    Journal Article
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    The use of recombinant antibodies in proteomics by Holt, Lucy J, Enever, Carolyn, de Wildt, Ruud MT, Tomlinson, Ian M

    Published in Current Opinion in Biotechnology (01-10-2000)
    “…Recombinant antibodies are becoming increasingly important in the field of proteomics. Recent advances include the development of large phage–antibody…”
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    Book Review Journal Article
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