Search Results - "Rutten, P."
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1
The environment and schizophrenia
Published in Nature (London) (11-11-2010)“…Psychotic syndromes can be understood as disorders of adaptation to social context. Although heritability is often emphasized, onset is associated with…”
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2
The Social Defeat Hypothesis of Schizophrenia: An Update
Published in Schizophrenia bulletin (01-11-2013)“…According to the social defeat (SD) hypothesis, published in 2005, long-term exposure to the experience of SD may lead to sensitization of the mesolimbic…”
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3
Gene-Environment Interactions in Schizophrenia: Review of Epidemiological Findings and Future Directions
Published in Schizophrenia bulletin (01-11-2008)“…Concern is building about high rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals, some of which likely…”
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4
Epigenetic Mediation of Environmental Influences in Major Psychotic Disorders
Published in Schizophrenia bulletin (01-11-2009)“…The major psychotic disorders schizophrenia and bipolar disorder are etiologically complex involving both heritable and nonheritable factors. The absence of…”
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5
Genetic profiling of Mycobacterium bovis strains from slaughtered cattle in Eritrea
Published in PLoS neglected tropical diseases (17-04-2018)“…Mycobacterium bovis (M.bovis) is the main causative agent for bovine tuberculosis (BTB) and can also be the cause of zoonotic tuberculosis in humans. In view…”
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6
Resilience in mental health: linking psychological and neurobiological perspectives
Published in Acta psychiatrica Scandinavica (01-07-2013)“…Objective To review the literature on psychological and biological findings on resilience (i.e. the successful adaptation and swift recovery after experiencing…”
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Epigenetic regulation of the BDNF gene: implications for psychiatric disorders
Published in Molecular psychiatry (01-06-2012)“…Abnormal brain-derived neurotrophic factor (BDNF) signaling seems to have a central role in the course and development of various neurological and psychiatric…”
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A time-lagged momentary assessment study on daily life physical activity and affect
Published in Health psychology (01-03-2012)“…Novel study designs using within-subject methodology and frequent and prospective measurements are required to unravel direction of causality and dynamic…”
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9
Clusters of Comorbidities Based on Validated Objective Measurements and Systemic Inflammation in Patients with Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-04-2013)“…Comorbidities contribute to disease severity and mortality in patients with chronic obstructive pulmonary disease (COPD). Comorbidities have been studied…”
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10
Leukemic stem cell frequency: a strong biomarker for clinical outcome in acute myeloid leukemia
Published in PloS one (22-09-2014)“…Treatment failure in acute myeloid leukemia is probably caused by the presence of leukemia initiating cells, also referred to as leukemic stem cells, at…”
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Development of Proteomic Prediction Models for Transition to Psychotic Disorder in the Clinical High-Risk State and Psychotic Experiences in Adolescence
Published in JAMA psychiatry (Chicago, Ill.) (01-01-2021)“…Biomarkers that are predictive of outcomes in individuals at risk of psychosis would facilitate individualized prognosis and stratification strategies. To…”
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12
Characterization of polarization states of canine monocyte derived macrophages
Published in PloS one (08-11-2023)“…Macrophages can reversibly polarize into multiple functional subsets depending on their micro-environment. Identification and understanding the functionality…”
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13
Ageing-in-place with the use of ambient intelligence technology: Perspectives of older users
Published in International journal of medical informatics (Shannon, Ireland) (01-05-2011)“…Highlights ► Ambient intelligence technologies are used to support ageing-in-place. ► The views and experiences of older users are not well studied. ► Ambient…”
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14
MicroRNA regulation of persistent stress-enhanced memory
Published in Molecular psychiatry (01-05-2020)“…Disruption of persistent, stress-associated memories is relevant for treating posttraumatic stress disorder (PTSD) and related syndromes, which develop in a…”
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15
MST1 Regulates Neuronal Cell Death via JNK/Casp3 Signaling Pathway in HFD Mouse Brain and HT22 Cells
Published in International journal of molecular sciences (21-05-2019)“…Oxidative stress has been considered as the main mediator in neurodegenerative diseases. A high-fat diet (HFD) and metabolic diseases result in oxidative…”
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Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress
Published in Molecular psychiatry (01-02-2021)“…The complement cascade is a major component of the immune defence against infection, and there is increasing evidence for a role of dysregulated complement in…”
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Adiponectin-mimetic novel nonapeptide rescues aberrant neuronal metabolic-associated memory deficits in Alzheimer's disease
Published in Molecular neurodegeneration (13-04-2021)“…Recently, we and other researchers reported that brain metabolic disorders are implicated in Alzheimer's disease (AD), a progressive, devastating and incurable…”
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Successful treatment of post-traumatic stress disorder reverses DNA methylation marks
Published in Molecular psychiatry (01-04-2021)“…Epigenetic mechanisms play a role in the detrimental effects of traumatic stress and the development of post-traumatic stress disorder (PTSD). However, it is…”
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Hsp70 and NF-kB Mediated Control of Innate Inflammatory Responses in a Canine Macrophage Cell Line
Published in International journal of molecular sciences (04-09-2020)“…The pathogenesis of many inflammatory diseases is associated with the uncontrolled activation of nuclear factor kappa B (NF-κB) in macrophages. Previous…”
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Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology
Published in Molecular psychiatry (01-11-2016)“…Human neural progenitors derived from pluripotent stem cells develop into electrophysiologically active neurons at heterogeneous rates, which can confound…”
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