Search Results - "Rutland, Cooper"
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The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry
Published in Biochemistry (Easton) (05-07-2017)“…OleT is a cytochrome P450 enzyme that catalyzes the removal of carbon dioxide from variable chain length fatty acids to form 1-alkenes. In this work, we…”
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Contemporary diagnostic approach to atypical vascular lesion and angiosarcoma
Published in Seminars in diagnostic pathology (01-07-2023)“…Vascular neoplasms account for a substantial fraction of cutaneous mesenchymal tumors, spanning from clinically indolent benign lesions to highly aggressive…”
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Diagnostic utility of FOXO1 immunohistochemistry for rhabdomyosarcoma classification
Published in Histopathology (01-07-2023)“…Aims Rhabdomyosarcomas currently are classified into one of four subtypes (alveolar, embryonal, spindle cell/sclerosing, or pleomorphic) according to their…”
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Mixed regiospecificity compromises alkene synthesis by a cytochrome P450 peroxygenase from Methylobacterium populi
Published in Journal of inorganic biochemistry (01-05-2016)“…Intensive interest has focused on enzymes that are capable of synthesizing hydrocarbons, alkenes and alkanes, for sustainable fuel production. A recently…”
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Targeted DNA Sequencing in Diagnosis of Malignant Phyllodes Tumors With Emphasis on Tumors With Keratin and p63 Expression
Published in Modern pathology (01-12-2024)“…The differential diagnosis of malignant spindle cell neoplasms in the breast most frequently rests between malignant phyllodes tumor (MPT) and metaplastic…”
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Enhancing ferryl accumulation in H2O2-dependent cytochrome P450s
Published in Journal of inorganic biochemistry (01-03-2024)“…A facile strategy is presented to enhance the accumulation of ferryl (iron(IV)-oxo) species in H2O2 dependent cytochrome P450s (CYPs) of the CYP152 family. We…”
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7
A Distal Loop Controls Product Release and Chemo- and Regioselectivity in Cytochrome P450 Decarboxylases
Published in Biochemistry (Easton) (23-01-2018)“…Cytochrome P450 OleT utilizes hydrogen peroxide (H2O2) to catalyze the decarboxylation or hydroxylation of fatty acid (FA) substrates. Both reactions are…”
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Acellular Dermal Matrix: Imaging Features With Histopathology Correlation
Published in Journal of breast imaging (09-09-2024)“…Acellular dermal matrix (ADM) is an immunologically inert graft, typically from cadaveric skin, often used in postmastectomy breast reconstruction. Created…”
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Myeloid sarcoma diagnosed on pleural effusion cytology: A case report and literature review
Published in Diagnostic cytopathology (01-08-2021)“…Myeloid sarcoma (MS) is a mass‐forming, extramedullary infiltration of myeloid blasts rarely presenting in cases of acute myeloid leukemia (AML). These tumoral…”
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10
Enhancing ferryl accumulation in H 2 O 2 -dependent cytochrome P450s
Published in Journal of inorganic biochemistry (01-03-2024)“…A facile strategy is presented to enhance the accumulation of ferryl (iron(IV)-oxo) species in H O dependent cytochrome P450s (CYPs) of the CYP152 family. We…”
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