Search Results - "Rutkowski, M."

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk by Stern, Jennifer H., Rutkowski, Joseph M., Scherer, Philipp E.

“…Metabolism research has made tremendous progress over the last several decades in establishing the adipocyte as a central rheostat in the regulation of…”
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The cell biology of fat expansion by Rutkowski, Joseph M, Stern, Jennifer H, Scherer, Philipp E

“…Adipose tissue is a complex, multicellular organ that profoundly influences the function of nearly all other organ systems through its diverse metabolite and…”
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Discrete mechanical model of lamellipodial actin network implements molecular clutch mechanism and generates arcs and microspikes by Rutkowski, David M, Vavylonis, Dimitrios

“…Mechanical forces, actin filament turnover, and adhesion to the extracellular environment regulate lamellipodial protrusions. Computational and mathematical…”
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An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State by Crewe, Clair, Joffin, Nolwenn, Rutkowski, Joseph M., Kim, Min, Zhang, Fang, Towler, Dwight A., Gordillo, Ruth, Scherer, Philipp E.

“…We have uncovered the existence of extracellular vesicle (EV)-mediated signaling between cell types within the adipose tissue (AT) proper. This phenomenon…”
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The far-ultraviolet continuum slope as a Lyman Continuum escape estimator at high redshift by Chisholm, J, Saldana-Lopez, A, Flury, S, Schaerer, D, Jaskot, A, Amorín, R, Atek, H, Finkelstein, S L, Fleming, B, Ferguson, H, Fernández, V, Giavalisco, M, Hayes, M, Heckman, T, Henry, A, Ji, Z, Marques-Chaves, R, Mauerhofer, V, McCandliss, S, Oey, M S, Östlin, G, Rutkowski, M, Scarlata, C, Thuan, T, Trebitsch, M, Wang, B, Worseck, G, Xu, X

“…ABSTRACT Most of the hydrogen in the intergalactic medium (IGM) was rapidly ionized at high redshifts. While observations have established that reionization…”
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VEGFR-3 signaling in macrophages: friend or foe in disease? by Kannan, Saranya, Rutkowski, Joseph M

“…Lymphatic vessels have been increasingly appreciated in the context of immunology not only as passive conduits for immune and cancer cell transport but also as…”
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Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival by Rutkowski, David M., Vincenzetti, Vincent, Vavylonis, Dimitrios, Martin, Sophie G.

“…Polarized exocytosis induced by local Cdc42 GTPase activity results in membrane flows that deplete low-mobility membrane-associated proteins. A…”
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Tactile and bone-conduction auditory brain computer interface for vision and hearing impaired users by Rutkowski, Tomasz M., Mori, Hiromu

“…•Novel multimodal tactile and bone-conduction BCI paradigm.•EEG signal processing methods leading to improved single-trial classification by applying…”
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Lymphangiogenesis: fuel, smoke, or extinguisher of inflammation’s fire? by Abouelkheir, Gabriella R, Upchurch, Bradley D, Rutkowski, Joseph M

“…Lymphangiogenesis is a recognized hallmark of inflammatory processes in tissues and organs as diverse as the skin, heart, bowel, and airways. In clinical and…”
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Mechanisms of obesity and related pathologies: The macro‐ and microcirculation of adipose tissue by Rutkowski, Joseph M., Davis, Kathryn E., Scherer, Philipp E.

“…Adipose tissue is an endocrine organ made up of adipocytes, various stromal cells, resident and infiltrating immune cells, and an extensive endothelial…”
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Neuronal and nonneuronal cholinergic structures in the mouse gastrointestinal tract and spleen by Gautron, Laurent, Rutkowski, Joseph M., Burton, Michael D., Wei, Wei, Wan, Yihong, Elmquist, Joel K.

“…ABSTRACT Accumulating evidence demonstrates that acetylcholine can directly modulate immune function in peripheral tissues including the spleen and…”
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Force transmission by retrograde actin flow-induced dynamic molecular stretching of Talin by Yamashiro, Sawako, Rutkowski, David M., Lynch, Kelli Ann, Liu, Ying, Vavylonis, Dimitrios, Watanabe, Naoki

“…Force transmission at integrin-based adhesions is important for cell migration and mechanosensing. Talin is an essential focal adhesion (FA) protein that links…”
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Vascular Endothelial Growth Factor–D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity by Chakraborty, Adri, Barajas, Sheridan, Lammoglia, Gabriela M., Reyna, Andrea J., Morley, Thomas S., Johnson, Joshua A., Scherer, Philipp E., Rutkowski, Joseph M.

“…Obese adipose tissue expansion is an inflammatory process that results in dysregulated lipolysis, increased circulating lipids, ectopic lipid deposition, and…”
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A driving force for change: interstitial flow as a morphoregulator by Rutkowski, Joseph M, Swartz, Melody A

“…Dynamic stresses that are present in all living tissues drive small fluid flows, called interstitial flows, through the extracellular matrix. Interstitial flow…”
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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin by Scherer, Philipp E, Holland, William L, Miller, Russell A, Wang, Zhao V, Sun, Kai, Barth, Brian M, Bui, Hai H, Davis, Kathryn E, Bikman, Benjamin T, Halberg, Nils, Rutkowski, Joseph M, Wade, Mark R, Tenorio, Vincent M, Kuo, Ming-Shang, Brozinick, Joseph T, Zhang, Bei B, Birnbaum, Morris J, Summers, Scott A

“…The protein hormone adiponectin is known to have many beneficial systemic effects, including promoting cell survival, anti-inflammation and insulin…”
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Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis by Duhon, Bailey H, Phan, Thien T, Taylor, Shannon L, Crescenzi, Rachelle L, Rutkowski, Joseph M

“…Lymphedema and lipedema are complex diseases. While the external presentation of swollen legs in lower-extremity lymphedema and lipedema appear similar,…”
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Immune cell trafficking, lymphatics and hypertension by Balasubbramanian, Dakshnapriya, Lopez Gelston, Catalina A, Rutkowski, Joseph M, Mitchell, Brett M

“…Activated immune cell infiltration into organs contributes to the development and maintenance of hypertension. Studies targeting specific immune cell…”
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Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium by Miteva, Dimana O, Rutkowski, Joseph M, Dixon, J Brandon, Kilarski, Witold, Shields, Jacqueline D, Swartz, Melody A

“…RATIONALE:Lymphatic transport of peripheral interstitial fluid and dendritic cells (DCs) is important for both adaptive immunity and maintenance of tolerance…”
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Enhancing Renal Lymphatic Expansion Prevents Hypertension in Mice by Lopez Gelston, Catalina A, Balasubbramanian, Dakshnapriya, Abouelkheir, Gabriella R, Lopez, Alexandra H, Hudson, Kayla R, Johnson, Eric R, Muthuchamy, Mariappan, Mitchell, Brett M, Rutkowski, Joseph M

“…RATIONALE:Hypertension is associated with renal infiltration of activated immune cells; however, the role of renal lymphatics and immune cell exfiltration is…”
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Mild cognitive impairment prediction and cognitive score regression in the elderly using EEG topological data analysis and machine learning with awareness assessed in affective reminiscent paradigm by Rutkowski, Tomasz M, Komendziński, Tomasz, Otake-Matsuura, Mihoko

“…The main objective of this study is to evaluate working memory and determine EEG biomarkers that can assist in the field of health neuroscience. Our ultimate…”
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