Search Results - "Rutkauskas, Marius"

Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection by Rutkauskas, Marius, Sinkunas, Tomas, Songailiene, Inga, Tikhomirova, Maria S., Siksnys, Virginijus, Seidel, Ralf

“…CRISPR-Cas systems provide bacteria and archaea with adaptive immunity against foreign nucleic acids. In type I CRISPR-Cas systems, invading DNA is detected by…”
Get full text

Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system by Aldag, Pierre, Rutkauskas, Marius, Madariaga-Marcos, Julene, Songailiene, Inga, Sinkunas, Tomas, Kemmerich, Felix, Kauert, Dominik, Siksnys, Virginijus, Seidel, Ralf

“…CRISPR-Cas effector complexes enable the defense against foreign nucleic acids and have recently been exploited as molecular tools for precise genome editing…”
Get full text

A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex by Rutkauskas, Marius, Songailiene, Inga, Irmisch, Patrick, Kemmerich, Felix E., Sinkunas, Tomas, Siksnys, Virginijus, Seidel, Ralf

“…CRISPR-Cas effector complexes recognise nucleic acid targets by base pairing with their crRNA which enables easy re-programming of the target specificity in…”
Get full text

Compressive hyperspectral imaging in the molecular fingerprint band by Charsley, Jake M., Rutkauskas, Marius, Altmann, Yoann, Risdonne, Valentina, Botticelli, Michela, Smith, Margaret J., Young, Christina R. T., Reid, Derryck T.

“…Spectrally-resolved imaging provides a spectrum for each pixel of an image that, in the mid-infrared, can enable its chemical composition to be mapped by…”
Get full text

Decision-Making in Cascade Complexes Harboring crRNAs of Altered Length by Songailiene, Inga, Rutkauskas, Marius, Sinkunas, Tomas, Manakova, Elena, Wittig, Sabine, Schmidt, Carla, Siksnys, Virginijus, Seidel, Ralf

“…The multi-subunit type I CRISPR-Cas surveillance complex Cascade uses its crRNA to recognize dsDNA targets. Recognition involves DNA unwinding and base-pairing…”
Get full text

Autonomous multi-species environmental gas sensing using drone-based Fourier-transform infrared spectroscopy by Rutkauskas, Marius, Asenov, Martin, Ramamoorthy, Subramanian, Reid, Derryck T.

Get full text

Supercontinuum generation in orientation-patterned gallium phosphide by Rutkauskas, Marius, Srivastava, Anchit, Reid, Derryck T.

“…Supercontinuum generation from nanojoule femtosecond lasers is well known in photonic-crystal fibers, channel waveguides, and micro-resonators, in which strong…”
Get full text

A Simple Thermodynamic Model for DNA-Strand Displacement Reactions in Presence of Base-Pair Mismatches by Irmisch, Patrick, Rutkauskas, Marius, Seidel, Ralf

Get full text

Probing the stability of the SpCas9–DNA complex after cleavage by Aldag, Pierre, Welzel, Fabian, Jakob, Leonhard, Schmidbauer, Andreas, Rutkauskas, Marius, Fettes, Fergus, Grohmann, Dina, Seidel, Ralf

“…Abstract CRISPR–Cas9 is a ribonucleoprotein complex that sequence-specifically binds and cleaves double-stranded DNA. Wildtype Cas9 and its nickase and…”
Get full text

Autonomous multi-species environmental gas sensing using drone-based Fourier-transform infrared spectroscopy by Rutkauskas, Marius, Asenov, Martin, Ramamoorthy, Subramanian, Reid, Derryck T

“…Unmanned aerial vehicles (UAVs)-or drones-present compelling new opportunities for airborne gas sensing in applications such as environmental monitoring,…”
Get full text

Modelling DNA-strand displacement reactions from single base-pair steps to reaction networks by Irmisch, Patrick, Rutkauskas, Marius, Del Grosso, Erica, Ricci, Francesco, Seidel, Ralf

Get full text

Open-path multi-species remote sensing with a broadband optical parametric oscillator by Kara, Oguzhan, Sweeney, Frazer, Rutkauskas, Marius, Farrell, C, Leburn, C G, Reid, Derryck T

“…Open-path remote sensing is critical for monitoring fugitive emissions from industrial sites, where a variety of volatile organic compounds may be released. At…”
Get full text

Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro by Krivoy, Andrey, Rutkauskas, Marius, Kuznedelov, Konstantin, Musharova, Olga, Rouillon, Christophe, Severinov, Konstantin, Seidel, Ralf

“…Abstract In type I CRISPR-Cas systems, primed adaptation of new spacers into CRISPR arrays occurs when the effector Cascade-crRNA complex recognizes…”
Get full text

The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex by Kauert, Dominik J., Madariaga-Marcos, Julene, Rutkauskas, Marius, Wulfken, Alexander, Songailiene, Inga, Sinkunas, Tomas, Siksnys, Virginijus, Seidel, Ralf

“…Clustered regularly interspaced short palindromic repeats (CRISPR) sequences and CRISPR-associated (Cas) genes comprise CIRSPR-Cas effector complexes, which…”
Get full text

Energy landscapes of CRISPR/Cas R-loop formation from ultrafast twist measurements by Madariaga Marcos, Julene, Kauert, Dominik J., Rutkauskas, Marius, Wulfken, Alexander, Songaliene, Inga, Sinkunas, Tomas, Siksnys, Virginijus, Seidel, Ralf

Get full text

Investigating and Modelling the Target Recognition Dynamics of the CRISPR-Cas Surveillance Complex Cascade by Rutkauskas, Marius, Sinkūnas, Tomas, Songailiene, Inga, Siksnys, Virginijus, Seidel, Ralf

Get full text

Dissecting the Target Recognition by CRISPR/Cas Effector Complexes with Ultrafast Twist Measurements by Madariaga Marcos, Julene, Kauert, Dominik J., Rutkauskas, Marius, Wulfken, Alexander, Songaliene, Inga, Sinkunas, Tomas, Siksnys, Virginijus, Seidel, Ralf

Get full text

Active Localization of Gas Leaks Using Fluid Simulation by Asenov, Martin, Rutkauskas, Marius, Reid, Derryck, Subr, Kartic, Ramamoorthy, Subramanian

“…Sensors are routinely mounted on robots to acquire various forms of measurements in spatiotemporal fields. Locating features within these fields and…”
Get full text

Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI by Tamulaitis, Gintautas, Rutkauskas, Marius, Zaremba, Mindaugas, Grazulis, Saulius, Tamulaitiene, Giedre, Siksnys, Virginijus

“…Type II restriction endonuclease BsaWI recognizes a degenerated sequence 5'-W/CCGGW-3' (W stands for A or T, '/' denotes the cleavage site). It belongs to a…”
Get full text

Reflecting the past, imag(in)ing the past: macro-reflection imaging of painting materials by fast MIR hyperspectral analysis by Botticelli, Michela, Risdonne, Valentina, Visser, Tess, Young, Christina, Smith, Margaret J., Charsley, Jake M., Rutkauskas, Marius, Altmann, Yoann, Reid, Derryck T.

“…Imaging spectroscopy has been developed in the last two decades in the visible and infrared spectral range for detecting pigments and binders on paintings. The…”
Get full text