Search Results - "Rutherford, Samantha"

Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures by Rutherford, Samantha J, Glenny, Anne-Marie, Roberts, Graham, Hooper, Lee, Worthington, Helen V

“…Infective endocarditis is a severe infection arising in the lining of the chambers of the heart. It can be caused by fungi, but most often is caused by…”
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Clinical Spectroscopy: Lost in Translation? by Cameron, James M., Rinaldi, Christopher, Rutherford, Samantha H., Sala, Alexandra, G. Theakstone, Ashton, Baker, Matthew J.

“…This Focal Point Review paper discusses the developments of biomedical Raman and infrared spectroscopy, and the recent strive towards these technologies being…”
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Detection of Glycine as a Model Protein in Blood Serum Using 2D-IR Spectroscopy by Rutherford, Samantha H, Greetham, Gregory M, Donaldson, Paul M, Towrie, Michael, Parker, Anthony W, Baker, Matthew J, Hunt, Neil T

“…Glycine (Gly) is used as a model system to evaluate the ability of ultrafast two-dimensional infrared (2D-IR) spectroscopy to detect and quantify the…”
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Optical Screening and Classification of Drug Binding to Proteins in Human Blood Serum by Rutherford, Samantha H, Hutchison, Christopher D M, Greetham, Gregory M, Parker, Anthony W, Nordon, Alison, Baker, Matthew J, Hunt, Neil T

“…Protein-drug interactions in the human bloodstream are important factors in applications ranging from drug design, where protein binding influences efficacy…”
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Differentiation of bacterial spores via 2D-IR spectroscopy by Procacci, Barbara, Rutherford, Samantha H., Greetham, Gregory M., Towrie, Michael, Parker, Anthony W., Robinson, Camilla V., Howle, Christopher R., Hunt, Neil T.

“…[Display omitted] •Ultrafast 2D-IR spectroscopic detection and classification of bacterial spores.•2D-IR spectra of Bacillus atrophaeus and Bacillus…”
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Citizen science to improve patient and public involvement in GUideline Implementation in oral health and DEntistry (the GUIDE platform) by Hosie, Annabel, Firdaus, Maria, Clarkson, Jan, Gupta, Ekta, Laidlaw, Lynn, Lamont, Thomas, Mooney, Margaret, Nevin, Gillian, Ramsay, Craig, Rutherford, Samantha, Sardo, Ana Margarida, Soulsby, Irene, Richards, Derek, Stirling, Douglas, West, Michele, Goulao, Beatriz

“…Background Citizen science is a way to democratise science by involving groups of citizens in the research process. Clinical guidelines are used to improve…”
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Bioprocess monitoring applications of an innovative ATR-FTIR spectroscopy platform by Christie, Loren, Rutherford, Samantha, Palmer, David S, Baker, Matthew J, Butler, Holly J

“…Pharmaceutical manufacturing is reliant upon bioprocessing approaches to generate the range of therapeutic products that are available today. The high cost of…”
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Preclinical pharmacology of sugammadex by Bom, Anton, MD, PhD, Hope, Frank, BSc, Rutherford, Samantha, PhD, Thomson, Karen, BSc

“…Abstract Since the introduction of nondepolarizing neuromuscular blocking agents, acetylcholinesterase inhibitors have been used to increase the speed of…”
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Fourier‐transform infrared spectroscopy of biofluids: A practical approach by Theakstone, Ashton G., Rinaldi, Christopher, Butler, Holly J., Cameron, James M., Confield, Lily Rose, Rutherford, Samantha H., Sala, Alexandra, Sangamnerkar, Sayali, Baker, Matthew J.

“…Biofluid spectroscopy is an emerging technology in the field of clinical investigation, providing a simple way to extract diagnostic and observational…”
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2- O-Substituted Cyclodextrins as Reversal Agents for the Neuromuscular Blocker Rocuronium Bromide by Tarver, Gary J, Grove, Simon J.A, Buchanan, Kirsteen, Bom, Anton, Cooke, Andrew, Rutherford, Samantha J, Zhang, Ming-Qiang

“…A series of secondary face modified cyclodextrins (CDs) were synthesised with the aim of constructing host molecules capable of forming host–guest complexes…”
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Biofluid analysis and classification using IR and 2D-IR spectroscopy by Rutherford, Samantha H., Nordon, Alison, Hunt, Neil T., Baker, Matthew J.

“…Vibrational spectroscopy has produced valuable information for biomedical research owing to its label-free and high-throughput capabilities. However, the…”
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2D-IR spectroscopy of proteins in H 2 O-A Perspective by Rutherford, Samantha H, Baker, Matthew J, Hunt, Neil T

“…The form of the amide I infrared absorption band provides a sensitive probe of the secondary structure and dynamics of proteins in the solution phase. However,…”
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Sustainable oral healthcare: what is it and how do we achieve it? by Beaton, Laura, Boyle, Jim, Cassie, Heather, Clarkson, Jan, Colthart, Iain, Duane, Brett, Duncan, Eilidh, Fennell-Wells, Amarantha, Felix, David H., Field, James, Fisher, Julian, Garbutt, David, Girdler, Jenny, Glenny, Anne-Marie, Glick, Michael, Goulao, Beatriz, Ikiroma, Adalia, Johansson, Minna, Jones, David, Martin, Nicolas, Mawdsley, Gillian, Nevin, Gillian, Ord, Fiona, O’Kane, Ciara, Purnell, Geoff, Ramsay, Craig, Robinson, Adam, Rutherford, Samantha, Salter, James, Stirling, Douglas, Tothill, Catherine, Walsh, Tanya, West, Michele, Wolff, Mark

“…In recent years, there has been an increase in interest in what environmental sustainability means for healthcare, including oral health and dentistry. To help…”
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Assessment of the Potential for Displacement Interactions with Sugammadex: A Pharmacokinetic-Pharmacodynamic Modelling Approach by Zwiers, Alex, van den Heuve, Michiel, Smeets, Jean, Rutherford, Samantha

“…Background: Sugammadex is a γ-cyclodextrin that binds with high affinity to the neuromuscular blocking agents (NMBAs) rocuronium (bromide) and vecuronium…”
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Assessment of the Potential for Displacement Interactions with Sugammadex: A Pharmacokinetic-Pharmacodynamic Modelling Approach by Zwiers, Alex, van den Heuvel, Michiel, Smeets, Jean, Rutherford, Samantha

“…Background: Sugammadex is a γ-cyclodextrin that binds with high affinity to the neuromuscular blocking agents (NMBAs) rocuronium (bromide) and vecuronium…”
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Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems by Fielding, Lee, Rutherford, Samantha, Fletcher, Dan

“…The usefulness of bovine serum albumin (BSA) as a model protein for testing NMR methods for the study of protein–ligand interactions is discussed. Isothermal…”
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Selective relaxant binding agents for reversal of neuromuscular blockade by Bom, Anton, Epemolu, Ola, Hope, Frank, Rutherford, Samantha, Thomson, Karen

“…Traditionally, reversal of neuromuscular blockade during anaesthesia was achieved by increasing the acetylcholine concentration in the neuromuscular junction…”
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Exploring the active site of human factor Xa protein by NMR screening of small molecule probes by Fielding, Lee, Fletcher, Dan, Rutherford, Samantha, Kaur, Jasmit, Mestres, Jordi

“…A collection of small molecules (MW < 350 Da) was screened for binding to human factor Xa using saturation transfer difference NMR spectroscopy to detect…”
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The Kinetics and Thermodynamics of Insulin Fibril Formation by Rutherford, Samantha Jane

“…Thermodynamics and Kinetics of Insulin Fibril Formation The deposition of amyloid, insoluble fibrillar aggregate composed of normally soluble cellular…”
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