Search Results - "Ruth N., Simmers"

Localization of the G-CSF Gene on Chromosome 17 Proximal to the Breakpoint in the t(15;17) in Acute Promyelocytic Leukemia by Ruth N., Simmers, Lorna M., Webber, M. Frances, Shannon, O. Margaret, Garson, Gordon, Wong, Mathew A., Vadas, Grant R., Sutherland

“…The human granulocyte-colony stimulating factor gene (G-CSF) is localized at 17q11.2-q21, the region of one of the breakpoints in the 15;17 chromosome…”
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Further localization of ETS1 indicates that the chromosomal rearrangement in Ewing sarcoma does not occur at fra(11)(q23) by SIMMERS, R. N, SUTHERLAND, G. R

“…A genomic probe homologous to 5.4 kb of the c-ets-1 gene was hybridized in situ to chromosomes expressing fra(11)(q23). This probe hybridized distal to the…”
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No statistical association between common fragile sites and nonrandom chromosome breakpoints in cancer cells by Sutherland, G R, Simmers, R N

“…Fragile sites and nonrandom chromosome breakpoints in cancer cells are not distributed at random within the genome, but occur mainly in the light G-bands. If…”
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