Search Results - "Rutecki, Paul"
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Nine-year prospective efficacy and safety of brain-responsive neurostimulation for focal epilepsy
Published in Neurology (01-09-2020)“…OBJECTIVETo prospectively evaluate safety and efficacy of brain-responsive neurostimulation in adults with medically intractable focal onset seizures (FOS)…”
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2-Deoxy-d-glucose reduces epileptiform activity by presynaptic mechanisms
Published in Journal of neurophysiology (01-04-2019)“…2-Deoxy-d-glucose (2DG), a glucose analog that inhibits glycolysis, has acute and chronic antiepileptic effects. We evaluated 2DG's acute effects on synaptic…”
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3
Brain‐responsive neurostimulation in patients with medically intractable mesial temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-06-2017)“…Summary Objective Evaluate the seizure‐reduction response and safety of mesial temporal lobe (MTL) brain‐responsive stimulation in adults with medically…”
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Two‐year seizure reduction in adults with medically intractable partial onset epilepsy treated with responsive neurostimulation: Final results of the RNS System Pivotal trial
Published in Epilepsia (Copenhagen) (01-03-2014)“…Summary Objective To demonstrate the safety and effectiveness of responsive stimulation at the seizure focus as an adjunctive therapy to reduce the frequency…”
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5
Lateralization of mesial temporal lobe epilepsy with chronic ambulatory electrocorticography
Published in Epilepsia (Copenhagen) (01-06-2015)“…Summary Objective Patients with suspected mesial temporal lobe (MTL) epilepsy typically undergo inpatient video–electroencephalography (EEG) monitoring with…”
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6
Genetic Background Influences Acute Response to TBI in Kindling-Susceptible, Kindling-Resistant, and Outbred Rats
Published in Frontiers in neurology (10-01-2020)“…We hypothesized that the acute response to traumatic brain injury (TBI) shares mechanisms with brain plasticity in the kindling model. Utilizing two unique,…”
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Treatment of drug-resistant epilepsy in patients with periventricular nodular heterotopia using RNS® System: Efficacy and description of chronic electrophysiological recordings
Published in Clinical neurophysiology (01-08-2019)“…•Periventricular nodular heterotopia (PVNH) can actively participate in epileptogenic networks.•Low voltage fast activity was the prominent seizure onset…”
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Long-Term Measurement of Impedance in Chronically Implanted Depth and Subdural Electrodes During Responsive Neurostimulation in Humans
Published in Brain stimulation (01-09-2013)“…Abstract Long-term stability of the electrode–tissue interface may be required to maintain optimal neural recording with subdural and deep brain implants and…”
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The Neurodevelopmental Impact of Childhood‐onset Temporal Lobe Epilepsy on Brain Structure and Function
Published in Epilepsia (Copenhagen) (01-09-2002)“…Purpose: To characterize the neurodevelopmental correlates of childhood‐onset temporal lobe epilepsy on brain structure and cognition compared with late‐onset…”
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Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling
Published in PLoS biology (01-08-2013)“…Tuberous sclerosis complex (TSC) is a multisystem genetic disease that manifests with mental retardation, tumor formation, autism, and epilepsy. Heightened…”
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Ipsilateral and Contralateral MRI Volumetric Abnormalities in Chronic Unilateral Temporal Lobe Epilepsy and their Clinical Correlates
Published in Epilepsia (Copenhagen) (01-03-2005)“…Purpose: To assess the presence, extent, and clinical correlates of quantitative MR volumetric abnormalities in ipsilateral and contralateral hippocampus, and…”
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Hippocampal abnormalities and sudden childhood death
Published in Forensic science, medicine, and pathology (01-06-2016)Get full text
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13
Spontaneous Seizures and Loss of Axo-Axonic and Axo-Somatic Inhibition Induced by Repeated Brief Seizures in Kindled Rats
Published in The Journal of neuroscience (01-04-2003)“…Repeated brief seizures evoked by kindling progressively increase seizure susceptibility and eventually induce spontaneous seizures. Previous studies have…”
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14
Fisher statistics for analysis of diffusion tensor directional information
Published in Journal of neuroscience methods (30-04-2012)“…A statistical approach is presented for the quantitative analysis of diffusion tensor imaging (DTI) directional information using Fisher statistics, which were…”
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15
CB1 receptor antagonism impairs the induction of epileptiform activity by group I metabotropic glutamate receptor activation
Published in Epilepsia (Copenhagen) (01-07-2010)“…Summary Exposure to the group I metabotropic glutamate receptor (mGluR) agonist dihydroxy phenylglycine (DHPG) induces epileptiform activity in the CA3 region…”
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16
Activity-dependent induction and maintenance of epileptiform activity produced by group I metabotropic glutamate receptors in the rat hippocampal slice
Published in Epilepsy research (01-09-2008)“…Summary Activation of group I metabotropic glutamate receptors (mGluRs) produces a long-lasting change in hippocampal excitability that persists in the absence…”
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A Case of Celiac Disease, Epilepsy, and Cerebral Calcifications With Temporal Lobe Epilepsy
Published in Wisconsin medical journal (Madison, Wis.) (01-06-2015)“…This is a case report of a 55-year-old man with medication refractory right temporal lobe epilepsy since adolescence. He was found to have bilateral posterior…”
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Anatomical, physiological, and theoretical basis for the antiepileptic effect of vagus nerve stimulation
Published in Epilepsia (Copenhagen) (01-01-1990)“…The vagus is a mixed nerve carrying somatic and visceral afferents and efferents. The majority of vagal nerve fibers are visceral afferents and have a wide…”
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Determinants of Ictal Epileptiform Patterns in the Hippocampal Slice
Published in Epilepsia (Copenhagen) (01-01-2002)“…Purpose: The transition from an interictal to an ictal pattern of epileptiform activity is a strategic target for antiepileptic drug (AED) action. Both the…”
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Inter- and intra-subject variability in gabapentin absorption and absolute bioavailability
Published in Epilepsy research (01-07-2000)“…Gabapentin (GBP) is a non-metabolized, non-plasma protein bound, renally excreted antiepileptic drug that is actively absorbed via the system L amino acid…”
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