Search Results - "Rutanen, Jarno"

COVID-19 clinical trials: learning from exceptions in the research chaos by Tikkinen, Kari A. O., Malekzadeh, Reza, Schlegel, Martin, Rutanen, Jarno, Glasziou, Paul

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Effect of remdesivir post hospitalization for COVID-19 infection from the randomized SOLIDARITY Finland trial by Nevalainen, Olli P. O., Horstia, Saana, Laakkonen, Sanna, Rutanen, Jarno, Mustonen, Jussi M. J., Kalliala, Ilkka E. J., Ansakorpi, Hanna, Kreivi, Hanna-Riikka, Kuutti, Pauliina, Paajanen, Juuso, Parkkila, Seppo, Paukkeri, Erja-Leena, Perola, Markus, Pourjamal, Negar, Renner, Andreas, Rosberg, Tuomas, Rutanen, Taija, Savolainen, Joni, Haukka, Jari K., Guyatt, Gordon H., Tikkinen, Kari A. O.

“…We report the first long-term follow-up of a randomized trial (NCT04978259) addressing the effects of remdesivir on recovery (primary outcome) and other…”
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Cost-effectiveness of abatacept, tocilizumab and TNF-inhibitors compared with rituximab as second-line biologic drug in rheumatoid arthritis by Huoponen, Saara, Aaltonen, Kalle J, Viikinkoski, Jaana, Rutanen, Jarno, Relas, Heikki, Taimen, Kirsi, Puolakka, Kari, Nordström, Dan, Blom, Marja

“…The objective of this study was to evaluate the cost-effectiveness of abatacept, tocilizumab, and tumor necrosis factor (TNF) inhibitors as compared with…”
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Public, health professional and legislator perspectives on the concept of psychiatric disease: a population-based survey by Tikkinen, Kari A O, Rutanen, Jarno, Frances, Allen, Perry, Brea L, Dennis, Brittany B, Agarwal, Arnav, Maqbool, Amna, Ebrahim, Shanil, Leinonen, Janne S, Järvinen, Teppo L N, Guyatt, Gordon H

“…ObjectiveTo assess which mental health-related states of being are perceived as diseases by psychiatrists, non-psychiatric physicians, nurses, parliament…”
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Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study by Boesgaard, Trine Welløv, Gjesing, Anette Prior, Grarup, Niels, Rutanen, Jarno, Jansson, Per-Anders, Hribal, Marta Letizia, Sesti, Giorgio, Fritsche, Andreas, Stefan, Norbert, Staiger, Harald, Häring, Hans, Smith, Ulf, Laakso, Markku, Pedersen, Oluf, Hansen, Torben

“…A meta-analysis combining results from three genome-wide association studies and followed by large-scale replication identified six novel type 2 diabetes loci…”
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Metabolic Syndrome, Disease Activity, and Adipokines in Patients With Newly Diagnosed Inflammatory Joint Diseases by Kononoff, Aulikki, Vuolteenaho, Katriina, Hämäläinen, Mari, Kautiainen, Hannu, Elfving, Pia, Savolainen, Elina, Arstila, Leena, Niinisalo, Helena, Rutanen, Jarno, Marjoniemi, Olga, Moilanen, Eeva, Kaipiainen-Seppänen, Oili

“…OBJECTIVETo investigate metabolic syndrome (MetS), disease activity, and adipokine levels among patients with rheumatoid arthritis (RA), spondyloarthritis…”
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Association of rheumatoid arthritis disease activity and antibodies to periodontal bacteria with serum lipoprotein profile in drug naive patients by Kononoff, Aulikki, Elfving, Pia, Pussinen, Pirkko, Hörkkö, Sohvi, Kautiainen, Hannu, Arstila, Leena, Laasonen, Leena, Savolainen, Elina, Niinisalo, Helena, Rutanen, Jarno, Marjoniemi, Olga, Hämäläinen, Mari, Vuolteenaho, Katriina, Moilanen, Eeva, Kaipiainen-Seppänen, Oili

“…Objective: We investigated lipid concentrations, particle sizes and antibodies binding to periodontal bacteria Aggregatibacter actinomycetemcomitans and…”
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SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity by RUTANEN, Jarno, YALURI, Nagendra, ELLIOTT, Peter, WESTPHAL, Christoph, AUWERX, Johan, LAAKSO, Markku, MODI, Shalem, PIHLAJAMÄKI, Jussi, VÄNTTINEN, Markku, ITKONEN, Paula, KAINULAINEN, Sakari, YAMAMOTO, Hiroyasu, LAGOUGE, Marie, SINCLAIR, David A

“…Sirtuin 1 (SIRT1) is implicated in the regulation of mitochondrial function, energy metabolism, and insulin sensitivity in rodents. No studies are available in…”
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Impact of TNF inhibitor medication on working ability in axial spondyloarthritis: an observational national registry-based cohort study by Hokkanen, Anna-Mari, Aaltonen, Kalle, Relas, Heikki, Rutanen, Jarno, Kononoff, Aulikki, Taimen, Kirsi, Kauppi, Markku, Puolakka, Kari, Trokovic, Nina, Nordström, Dan

“…Abstract Objective The aim was to investigate the effect of TNF inhibitor (TNFi) initiation on working ability and health-care resource utilization among…”
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MP57-03 DECISION AIDS FOR PROSTATE CANCER SCREENING: A SYSTEMATIC REVIEW AND META-ANALYSIS by Riikonen, Jarno, Guyatt, Gordon, Kilpeläinen, Tuomas P, Craigie, Samantha, Agarwal, Arnav, Agoritsas, Thomas, Couban, Rachel, Dahm, Philipp, Järvinen, Petrus, Montori, Victor, Power, Nicholas, Richard, Patrick O, Rutanen, Jarno, Santti, Henrikki, Tailly, Thomas, Violette, Philippe D, Zhou, Qi, Tikkinen, Kari A O

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Immunogenicity of subcutaneous TNF inhibitors and its clinical significance in real-life setting in patients with spondyloarthritis by Hiltunen, J., Parmanne, P., Sokka, T., Lamberg, T., Isomäki, P., Kaipiainen-Seppänen, O., Peltomaa, R., Uutela, T., Pirilä, L., Taimen, K., Kauppi, M. J., Yli-Kerttula, T., Tuompo, R., Relas, H., Kortelainen, S., Paalanen, K., Asikainen, J., Ekman, P., Santisteban, A., Vidqvist, K.-L., Tadesse, K., Romu, M., Borodina, J., Elfving, P., Valleala, H., Leirisalo-Repo, M., Rantalaiho, V., Kautiainen, H., Jokiranta, T. S., Eklund, K. K.

“…Key messages Considerable proportion of patients with SpA have been immunized to the subcutaneous anti-TNF drug they are using. Concomitant use of MTX protects…”
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1126. Effect of Remdesivir on Recovery, Quality of Life, and Long-COVID Symptoms One Year after Hospitalization for COVID-19 Infection: A Randomized Controlled SOLIDARITY Finland Trial by Nevalainen, Olli P O, Horstia, Saana, Laakkonen, Sanna, Rutanen, Jarno, Mustonen, Jussi, Kalliala, Ilkka, Ansakorpi, Hanna, Kreivi, Hanna-Riikka, Kuutti, Pauliina, Paajanen, Juuso, Parkkila, Seppo, Paukkeri, Erja-Leena, Perola, Markus, Pourjamal, Negar, Renner, Andreas, Rosberg, Tuomas, Rutanen, Taija, Savolainen, Joni, Haukka, Jari K, Guyatt, Gordon H, Tikkinen, Kari A

“…Abstract Background Coronavirus disease 2019 (COVID-19) patients frequently suffer from long-term sequelae, often called “long COVID” or “post COVID-19…”
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Single Nucleotide Polymorphisms of the MCHR1 Gene Do Not Affect Metabolism in Humans by Rutanen, Jarno, Pihlajamäki, Jussi, Vänttinen, Markku, Salmenniemi, Urpu, Ruotsalainen, Eija, Kuulasmaa, Teemu, Kainulainen, Sakari, Kuusisto, Johanna, Laakso, Markku

“…Melanin concentrating hormone receptor‐1 (MCHR1) is a centrally and peripherally expressed receptor that regulates energy expenditure and appetite. Single…”
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Single Nucleotide Polymorphisms of the Melanocortin-3 Receptor Gene Are Associated with Substrate Oxidation and First-Phase Insulin Secretion in Offspring of Type 2 Diabetic Subjects by Rutanen, Jarno, Pihlajamäki, Jussi, Vänttinen, Markku, Salmenniemi, Urpu, Ruotsalainen, Eija, Kuulasmaa, Teemu, Kainulainen, Sakari, Laakso, Markku

“…Context: The melanocortin-3 receptor (MC3R) is a part of the melanocortin system that regulates appetite and energy metabolism. The Lys/Thr6 and Ile/Val81…”
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Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain by Rutanen, J, Pihlajamaki, J, Karhapaa, P, Vauhkonen, I, Kuusisto, J, Mykkanen, L.M, Laakso, M

“…Objective: The melanocortin‐4 receptor (MC4R) regulates energy intake. On the basis of animal studies, it may also regulate energy expenditure. Research…”
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