Search Results - "Ruszkiewicz, Andrew R"

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer by Day, Fiona L, Jorissen, Robert N, Lipton, Lara, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Christie, Michael, Li, Shan, Tsui, Cary, Tie, Jeannie, Desai, Jayesh, Xu, Zheng-Zhou, Molloy, Peter, Whitehall, Vicki, Leggett, Barbara A, Jones, Ian T, McLaughlin, Stephen, Ward, Robyn L, Hawkins, Nicholas J, Ruszkiewicz, Andrew R, Moore, James, Busam, Dana, Zhao, Qi, Strausberg, Robert L, Gibbs, Peter, Sieber, Oliver M

“…PIK3CA and PTEN mutations are prevalent in colorectal cancer and potential markers of response to mitogen-activated protein/extracellular signal-regulated…”
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Pathology Features in Bethesda Guidelines Predict Colorectal Cancer Microsatellite Instability: A Population-Based Study by Jenkins, Mark A, Hayashi, Shinichi, O’Shea, Anne-Marie, Burgart, Lawrence J, Smyrk, Tom C, Shimizu, David, Waring, Paul M, Ruszkiewicz, Andrew R, Pollett, Aaron F, Redston, Mark, Barker, Melissa A, Baron, John A, Casey, Graham R, Dowty, James G, Giles, Graham G, Limburg, Paul, Newcomb, Polly, Young, Joanne P, Walsh, Michael D, Thibodeau, Stephen N, Lindor, Noralane M, LeMarchand, Loïc, Gallinger, Steven, Haile, Robert W, Potter, John D, Hopper, John L, Jass, Jeremy R

“…Background & Aims: The revised Bethesda guidelines for Lynch syndrome recommend microsatellite instability (MSI) testing all colorectal cancers in patients…”
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Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer by Jorissen, Robert N, Christie, Michael, Mouradov, Dmitri, Sakthianandeswaren, Anuratha, Li, Shan, Love, Christopher, Xu, Zheng-Zhou, Molloy, Peter L, Jones, Ian T, McLaughlin, Stephen, Ward, Robyn L, Hawkins, Nicholas J, Ruszkiewicz, Andrew R, Moore, James, Burgess, Antony W, Busam, Dana, Zhao, Qi, Strausberg, Robert L, Lipton, Lara, Desai, Jayesh, Gibbs, Peter, Sieber, Oliver M

“…Background: APC mutations ( APC -mt) occur in ∼70% of colorectal cancers (CRCs), but their relationship to prognosis is unclear. Methods: APC prognostic value…”
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Improving the Accuracy of TNM Staging in Esophageal Cancer: A Pathological Review of Resected Specimens by Thompson, Sarah K., Ruszkiewicz, Andrew R., Jamieson, Glyn G., Esterman, Adrian, Watson, David I., Wijnhoven, Bas P. L., Lamb, Peter J., Devitt, Peter G.

“…Background Controversy exists over the Sixth Edition of the International Union Against Cancer (UICC) TNM staging system for esophageal cancer. Inclusion of…”
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Similarity of aberrant DNA methylation in Barrett's esophagus and esophageal adenocarcinoma by Smith, Eric, De Young, Neville J, Pavey, Sandra J, Hayward, Nicholas K, Nancarrow, Derek J, Whiteman, David C, Smithers, B Mark, Ruszkiewicz, Andrew R, Clouston, Andrew D, Gotley, David C, Devitt, Peter G, Jamieson, Glyn G, Drew, Paul A

“…Barrett's esophagus (BE) is the metaplastic replacement of squamous with columnar epithelium in the esophagus, as a result of reflux. It is the major risk…”
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Association Between RAS/BRAF Mutations and Complete Response Following Total Neoadjuvant Therapy in Patients with Rectal Cancer: A Prospective Multicentered Study by Bedrikovetski, Sergei, Traeger, Luke, Fitzsimmons, Tracy, Price, Timothy J., Ruszkiewicz, Andrew R., Vather, Ryash, Sammour, Tarik

“…Background The impact of RAS/BRAF mutation on primary response rates after total neoadjuvant therapy (TNT) in patients with advanced rectal cancer is unclear…”
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ASO Visual Abstract: Association Between RAS/BRAF Mutations and Complete Response After Total Neoadjuvant Therapy of Patients with Rectal Cancer: A Prospective Multicentered Study by Bedrikovetski, Sergei, Traeger, Luke, Fitzsimmons, Tracy, Price, Timothy J., Ruszkiewicz, Andrew R., Vather, Ryash, Sammour, Tarik

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SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer by FLEMING, Nicholas I, JORISSEN, Robert N, DESAI, Jayesh, JONES, Ian T, MCLAUGHLIN, Stephen, WARD, Robyn L, HAWKINS, Nicholas J, RUSZKIEWICZ, Andrew R, MOORE, James, ZHU, Hong-Jian, MARIADASON, John M, BURGESS, Antony W, MOURADOV, Dmitri, BUSAM, Dana, QI ZHAO, STRAUSBERG, Robert L, GIBBS, Peter, SIEBER, Oliver M, CHRISTIE, Michael, SAKTHIANANDESWAREN, Anuratha, PALMIERI, Michelle, DAY, Fiona, SHAN LI, TSUI, Cary, LIPTON, Lara

“…Activation of the canonical TGF-β signaling pathway provides growth inhibitory signals in the normal intestinal epithelium. Colorectal cancers (CRCs)…”
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Methylation of TIMP3 in esophageal squamous cell carcinoma by Smith, Eric, De Young, Neville J, Tian, Zi-Qiang, Caruso, Maria, Ruszkiewicz, Andrew R, Liu, Jun-Feng, Jamieson, Glyn G, Drew, Paul A

“…AIM： To measure the frequency of DNA methylation of the tissue inhibitor of metalloproteinase 3 （TIMP3） promoter and relate this to any change of gene…”
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Isolated Loss of PMS2 Expression in Colorectal Cancers: Frequency, Patient Age, and Familial Aggregation by GILL, Sharlene, LINDOR, Noralane M, JENKINS, Mark A, YOUNG, Joanne, BARKER, Melissa A, WALSH, Michael D, RUSZKIEWICZ, Andrew R, THIBODEAU, Stephen N, BURGART, Lawrence J, SMALLEY, Regenia, LEONTOVICH, Olga, FRENCH, Amy J, GOLDBERG, Richard M, SARGENT, Daniel J, JASS, Jeremy R, HOPPER, John L

“…Purpose: Most colorectal cancers that have high levels of microsatellite instability (MSI-H) show loss of immunohistochemical expression of proteins that…”
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HER-2/neu Gene Amplification in Esophageal Adenocarcinoma and Its Influence on Survival by Thompson, Sarah K., Sullivan, Thomas R., Davies, Ruth, Ruszkiewicz, Andrew R.

“…Background HER-2/ neu (c- erb B-2, HER2) gene amplification and protein overexpression have been associated with poor prognosis in several solid tumors,…”
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Metallothionien 3 expression is frequently down-regulated in oesophageal squamous cell carcinoma by DNA methylation by Smith, Eric, Drew, Paul A, Tian, Zi-Qing, De Young, Neville J, Liu, Jun-Feng, Mayne, George C, Ruszkiewicz, Andrew R, Watson, David I, Jamieson, Glyn G

“…Metallothionein 3 (MT3) inhibits growth in a variety of cell types. We measured MT3 gene expression by RT-PCR, and DNA methylation in the MT3 promoter by…”
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Identification of microRNA Biomarkers of Response to Neoadjuvant Chemoradiotherapy in Esophageal Adenocarcinoma Using Next Generation Sequencing by Chiam, Karen, Mayne, George C., Watson, David I., Woodman, Richard J., Bright, Tim F., Michael, Michael Z., Karapetis, Christos S., Irvine, Tanya, Phillips, Wayne A., Hummel, Richard, Wang, Tingting, Pimlott, Letitia K., Marri, Shashikanth, Astill, David StJ, Ruszkiewicz, Andrew R., Thompson, Sarah K., Hussey, Damian J.

“…Background Clinical trials report improved overall survival following neoadjuvant chemoradiotherapy in patients undergoing surgery for esophageal…”
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Verrucous carcinoma of the oesophagus by Hoffmann, Richard, Hebenstreit, Annie, Game, Philip A., Ruszkiewicz, Andrew R., Thompson, Sarah K.

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Androgen Receptor and Androgen-Responsive Gene FKBP5 Are Independent Prognostic Indicators for Esophageal Adenocarcinoma by Smith, Eric, Palethorpe, Helen M., Ruszkiewicz, Andrew R., Edwards, Suzanne, Leach, Damien A., Underwood, Tim J., Need, Eleanor F., Drew, Paul A.

“…Background Esophageal adenocarcinoma is a male-dominant disease, but the role of androgens is unclear. Aims To examine the expression and clinical correlates…”
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Young‐onset colorectal cancer is associated with a personal history of type 2 diabetes by Mikaeel, Reger R., Symonds, Erin L., Kimber, James, Smith, Eric, Horsnell, Mehgan, Uylaki, Wendy, Tapia Rico, Gonzalo, Hewett, Peter J., Yong, Jonathan, Tonkin, Darren, Jesudason, David, Poplawski, Nicola K., Ruszkiewicz, Andrew R., Drew, Paul A., Hardingham, Jenny E., Wong, Stephanie, Frank, Oliver, Tomita, Yoko, Patel, Dainik, Vatandoust, Sina, Townsend, Amanda R., Roder, David, Young, Graeme P., Parry, Susan, Tomlinson, Ian P., Wittert, Gary, Wattchow, David, Worthley, Daniel L., Brooks, William J., Price, Timothy J., Young, Joanne P.

“…Background Colorectal cancer (CRC) is rising in incidence in young adults, and this observation is currently unexplained. We investigated whether having a…”
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Human intestinal spirochetosis and its relationship to sessile serrated adenomas in an Australian population by Young, Joanne P., Price, Timothy J., Moore, James, Ruszkiewicz, Andrew R.

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Isolated Tumor Cells in Esophageal Cancer: Implications for the Surgeon and the Pathologist by THOMPSON, Sarah K, RUSZKIEWICZ, Andrew R, JAMIESON, Glyn G, SULLIVAN, Thomas R, DEVITT, Peter G

“…Studies suggest that up to 56% of node-negative patients have tumor deposits in their lymph nodes that are missed by routine pathologic examination. However,…”
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Clinicopathological predictors of benefit from adjuvant chemotherapy for stage C colorectal cancer: Microsatellite unstable cases benefit by Thomas, Michelle L, Hewett, Peter J, Ruszkiewicz, Andrew R, Moore, James WE

“…Aim In colorectal cancer (CRC), adjuvant therapy is offered on the basis of stage and attempts to identify factors to better target treatment have not been…”
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Feasibility study of sentinel lymph node biopsy in esophageal cancer with conservative lymphadenectomy by Thompson, Sarah K., Bartholomeusz, Dylan, Devitt, Peter G., Lamb, Peter J., Ruszkiewicz, Andrew R., Jamieson, Glyn G.

“…Introduction Lymphoscintigraphy and sentinel node mapping is established in breast cancer and melanoma but not in esophageal cancer, even though many centers…”
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