Search Results - "Ruswa, Nunurai"
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Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia
Published in Emerging infectious diseases (01-03-2024)“…Bedaquiline is currently a key drug for treating multidrug-resistant or rifampin-resistant tuberculosis. We report and discuss the unusual development of…”
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Enhanced active case finding of drug-resistant tuberculosis in Namibia: a protocol for the hotspots, hospitals, and households (H3TB) study
Published in BMJ open (10-02-2024)“…IntroductionNamibia is a high tuberculosis (TB)-burden country with an estimated incidence of 460/100 000 (around 12 000 cases) per year. Approximately 4.5% of…”
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Implementation of targeted next-generation sequencing for the diagnosis of drug-resistant tuberculosis in low-resource settings: a programmatic model, challenges, and initial outcomes
Published in Frontiers in public health (03-08-2023)“…Targeted next-generation sequencing (tNGS) from clinical specimens has the potential to become a comprehensive tool for routine drug-resistance (DR) prediction…”
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Drug-Resistant Tuberculosis Case-Finding Strategies: Scoping Review
Published in JMIR public health and surveillance (26-06-2024)“…Finding individuals with drug-resistant tuberculosis (DR-TB) is important to control the pandemic and improve patient clinical outcomes. To our knowledge,…”
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Occurrence and clinical management of moderate-to-severe adverse events during drug-resistant tuberculosis treatment: a retrospective cohort study
Published in Journal of pharmaceutical policy and practice (21-10-2014)“…To determine the incidence of symptomatic moderate-to-severe adverse events during treatment of drug-resistant tuberculosis, and to compare their risk and…”
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Case-Finding Strategies for Drug-Resistant Tuberculosis: Protocol for a Scoping Review
Published in JMIR research protocols (15-12-2022)“…Transmission of drug-resistant tuberculosis (DR-TB) is ongoing. Finding individuals with DR-TB and initiating treatment as early as possible is important to…”
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Predictors of loss to follow-up of tuberculosis cases under the DOTS programme in Namibia
Published in ERJ open research (01-01-2020)“…In Namibia, one out of every 25 cases of tuberculosis (TB) is "lost to follow-up" (LTFU). This has impacted negatively on national efforts to end the disease…”
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Drug-resistant tuberculosis: advances in diagnosis and management
Published in Current opinion in pulmonary medicine (25-02-2022)Get full text
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Drug-resistant tuberculosis: advances in diagnosis and management
Published in Current opinion in pulmonary medicine (01-05-2022)“…Diagnosis and treatment of drug-resistant tuberculosis (DR-TB) is undergoing substantial changes, owing availability of new diagnostic tools and drugs, coupled…”
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Prevalence of subclinical pulmonary tuberculosis in adults in community settings: an individual participant data meta-analysis
Published in The Lancet infectious diseases (01-07-2024)“…Subclinical pulmonary tuberculosis, which presents without recognisable symptoms, is frequently detected in community screening. However, the disease category…”
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Adverse Events During Treatment of Drug-Resistant Tuberculosis: A Comparison Between Patients With or Without Human Immunodeficiency Virus Co-infection
Published in Drug safety (01-11-2013)“…Introduction In settings such as Namibia with a high prevalence of human immunodeficiency virus (HIV) and drug-resistant (DR) tuberculosis (TB) co-infection,…”
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Comparing amikacin and kanamycin-induced hearing loss in multidrug-resistant tuberculosis treatment under programmatic conditions in a Namibian retrospective cohort
Published in BMC pharmacology & toxicology (10-12-2015)“…Amikacin and kanamycin are mainly used for treating multidrug-resistant tuberculosis (MDR-TB), especially in developing countries where the burden of MDR-TB is…”
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Predictors of tuberculosis treatment success under the DOTS program in Namibia
Published in Expert review of respiratory medicine (02-11-2018)“…Optimal treatment success rates are critical to end tuberculosis in Namibia. Despite the scale-up of high quality directly observed therapy short-course…”
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Association of diabetes, smoking, and alcohol use with subclinical-to-symptomatic spectrum of tuberculosis in 16 countries: an individual participant data meta-analysis of national tuberculosis prevalence surveys
Published in EClinicalMedicine (01-09-2023)“…Non-communicable diseases (NCDs) and NCD risk factors, such as smoking, increase the risk for tuberculosis (TB). Data are scarce on the risk of prevalent TB…”
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Tobacco smoking clusters in households affected by tuberculosis in an individual participant data meta-analysis of national tuberculosis prevalence surveys: Time for household-wide interventions?
Published in PLOS global public health (2024)“…Tuberculosis (TB) and non-communicable diseases (NCD) share predisposing risk factors. TB-associated NCD might cluster within households affected with TB…”
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Association of diabetes, smoking, and alcohol use with subclinical-to-symptomatic spectrum of tuberculosis in 16 countries: an individual participant data meta-analysis of national tuberculosis prevalence surveysResearch in context
Published in EClinicalMedicine (01-09-2023)“…Background: Non-communicable diseases (NCDs) and NCD risk factors, such as smoking, increase the risk for tuberculosis (TB). Data are scarce on the risk of…”
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Adverse events and patients' perceived health-related quality of life at the end of multidrug-resistant tuberculosis treatment in Namibia
Published in Patient preference and adherence (01-01-2016)“…The health-related quality of life (HRQoL) of patients completing multidrug-resistant tuberculosis (MDR-TB) treatment in Namibia and whether the occurrence of…”
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TB Control in Namibia 2002-2011: Progress and Technical Assistance
Published in The open infectious diseases journal (19-04-2013)Get full text
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The burden of adverse events during treatment of drug-resistant tuberculosis in Namibia
Published in Southern med review (01-07-2012)“…Namibia faces a dual burden of HIV/AIDS and tuberculosis (TB). In 2010, HIV prevalence was 18.8%, the TB case notification rate was 634 cases per 100,000…”
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