Search Results - "Rustiguel, Joane K."

Structural, biochemical and biophysical characterization of recombinant human fumarate hydratase by Ajalla Aleixo, Mariana A., Rangel, Victor L., Rustiguel, Joane K., de Pádua, Ricardo A. P., Nonato, Maria Cristina

“…Fumarate hydratases (FHs, fumarases) catalyze the reversible conversion of fumarate into l‐malate. FHs are distributed over all organisms and play important…”
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Crystal structure and molecular dynamics studies of L-amino acid oxidase from Bothrops atrox by Feliciano, Patricia R., Rustiguel, Joane K., Soares, Ricardo O.S., Sampaio, Suely V., Cristina Nonato, M.

“…L-amino acid oxidases (LAAOs) are dimeric flavoproteins that catalyze the deamination of L-amino acid to α-keto acid, producing ammonia and hydrogen peroxide…”
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Insights into the structure, function and stability of bordonein-L, the first L-amino acid oxidase from Crotalus durissus terrificus snake venom by Wiezel, Gisele A., Rustiguel, Joane K., Morgenstern, David, Zoccal, Karina F., Faccioli, Lucia H., Nonato, M. Cristina, Ueberheide, Beatrix, Arantes, Eliane C.

“…Snake venom L-amino acid oxidases (svLAAOs) are an interesting class of enzymes with important biological activities. Their participation in key metabolic…”
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Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia by Lewis, Timothy A, Sykes, David B, Law, Jason M, Muñoz, Benito, Rustiguel, Joane K, Nonato, Maria Cristina, Scadden, David T, Schreiber, Stuart L

“…Homeobox transcription factor A9 (HoxA9) is overexpressed in 70% of patients diagnosed with acute myeloid leukemia (AML), whereas only a small subset of AML…”
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Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityus serrulatus venom by Cologna, Camila T., Peigneur, Steve, Rustiguel, Joane K., Nonato, M. Cristina, Tytgat, Jan, Arantes, Eliane C.

“…Scorpion toxins targeting voltage‐gated sodium (NaV) channels are peptides that comprise 60–76 amino acid residues cross‐linked by four disulfide bridges…”
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Full-length model of the human galectin-4 and insights into dynamics of inter-domain communication by Rustiguel, Joane K., Soares, Ricardo O. S., Meisburger, Steve P., Davis, Katherine M., Malzbender, Kristina L., Ando, Nozomi, Dias-Baruffi, Marcelo, Nonato, Maria Cristina

“…Galectins are proteins involved in diverse cellular contexts due to their capacity to decipher and respond to the information encoded by β-galactoside sugars…”
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Recombinant expression, purification and preliminary biophysical and structural studies of C-terminal carbohydrate recognition domain from human galectin-4 by Rustiguel, Joane K., Kumagai, Patricia S., Dias-Baruffi, Marcelo, Costa-Filho, Antonio J., Nonato, Maria Cristina

“…Galectin-4 (Gal4), a tandem-repeat type galectin, is expressed in healthy epithelium of the gastrointestinal tract. Altered levels of Gal4 expression are…”
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NP 3 : an integrated platform for natural product-based drug discovery centred on X-ray protein crystallography by Trivella, Daniela B. B., Rustiguel, Joane K., Bazzano, Cristina F., de Felicio, Rafael, Alves, Luiz G., Meneghello, Raphael, Cunha, Marcos G., Telles, Guilherme, Nascimento, Andrey Z., Zeri, Ana C. M.

“…Abstract only…”
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Purification, partial characterization and preliminary X-ray diffraction analysis of a mannose-specific lectin from Cymbosema roseum seeds by Cavada, Benildo S., Marinho, Emmanuel S., Souza, Emmanuel P., Benevides, Raquel G., Delatorre, Plínio, Souza, Luis A. G., Nascimento, Kyria S., Sampaio, Alexandre H., Moreno, Frederico B. M. B., Rustiguel, Joane K. R., Canduri, Fernanda, De Azevedo Jr, Walter F., Debray, Henri

“…A lectin from Cymbosema roseum seeds (CRL) was purified, characterized and crystallized. The best crystals grew in a month and were obtained by the…”
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Investigation of the relationship between the structure and function of Ts2, a neurotoxin from Tityusserrulatus venom by Cologna, Camila T, Peigneur, Steve, Rustiguel, Joane K, Nonato, M. Cristina, Tytgat, Jan, Arantes, Eliane C

“…Scorpion toxins targeting voltage-gated sodium (NaV) channels are peptides that comprise 60-76 amino acid residues cross-linked by four disulfide bridges…”
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Understanding Chlorocatechol 1,2-Dioxygenase Function: A Promising Player in Bioremediation Processes by Mesquita, Nathalya C., Rustiguel, Joane K., Melo, Fernando A., Citadini, Ana P., Pinto, Andressa P., Paula U. Araújo, Ana, Nonato, M. Cristina, Costa-Filho, Antonio J.

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