Search Results - "Rustenburg, F"
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Rheumatoid arthritis subtypes identified by genomic profiling of peripheral blood cells: assignment of a type I interferon signature in a subpopulation of patients
Published in Annals of the rheumatic diseases (01-08-2007)“…Background: Rheumatoid arthritis (RA) is a heterogeneous disease with unknown cause. Aim: To identify peripheral blood (PB) gene expression profiles that may…”
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Responsiveness to anti-tumour necrosis factor alpha therapy is related to pre-treatment tissue inflammation levels in rheumatoid arthritis patients
Published in Annals of the rheumatic diseases (01-04-2008)“…The response of rheumatoid arthritis (RA) patients to treatment with neutralising antibodies to tumour necrosis factor alpha (TNFalpha) is highly variable. The…”
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Pharmacogenomics of infliximab treatment using peripheral blood cells of patients with rheumatoid arthritis
Published in Genes and immunity (01-12-2010)“…To provide insight into the pharmacological changes in the peripheral blood (PB) molecular profile induced by tumor necrosis factor (TNF)-blockade in patients…”
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A subtype of multiple sclerosis defined by an activated immune defense program
Published in Genes and immunity (01-09-2006)“…Given the heterogeneous nature of multiple sclerosis (MS), we applied DNA microarray technology to determine whether variability is reflected in peripheral…”
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Expression of a pathogen-response program in peripheral blood cells defines a subgroup of Rheumatoid Arthritis patients
Published in Genes and immunity (01-01-2008)“…Rheumatoid arthritis (RA) is a heterogeneous disease with unknown etiology. Here we aimed to distinguish RA subtypes based on peripheral blood (PB) gene…”
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Molecular subtypes of systemic sclerosis in association with anti-centromere antibodies and digital ulcers
Published in Genes and immunity (01-04-2009)“…The objective of this study was to identify molecular profiles that may distinguish clinical subtypes in systemic sclerosis (SSc). Large-scale gene expression…”
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Regulation of interferon response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment
Published in Arthritis research & therapy (01-01-2010)“…Introduction Cross-regulation between tumor necrosis factor (TNF) and type I interferon (IFN) has been postulated to play an important role in autoimmune…”
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Rheumatoid arthritis: a heterogeneous disease evaluated by DNA-microarray technology
Published in Arthritis research & therapy (2004)Get full text
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