Search Results - "Rustad, Tige"

The enduring hypoxic response of Mycobacterium tuberculosis by Rustad, Tige R, Harrell, Maria I, Liao, Reiling, Sherman, David R

“…A significant body of evidence accumulated over the last century suggests a link between hypoxic microenvironments within the infected host and the latent…”
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Integrated Modeling of Gene Regulatory and Metabolic Networks in Mycobacterium tuberculosis by Ma, Shuyi, Minch, Kyle J, Rustad, Tige R, Hobbs, Samuel, Zhou, Suk-Lin, Sherman, David R, Price, Nathan D

“…Mycobacterium tuberculosis (MTB) is the causative bacterium of tuberculosis, a disease responsible for over a million deaths worldwide annually with a growing…”
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The DNA-binding network of Mycobacterium tuberculosis by Minch, Kyle J., Rustad, Tige R., Peterson, Eliza J. R., Winkler, Jessica, Reiss, David J., Ma, Shuyi, Hickey, Mark, Brabant, William, Morrison, Bob, Turkarslan, Serdar, Mawhinney, Chris, Galagan, James E., Price, Nathan D., Baliga, Nitin S., Sherman, David R.

“…Mycobacterium tuberculosis (MTB) infects 30% of all humans and kills someone every 20–30 s. Here we report genome-wide binding for ~80% of all predicted MTB…”
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Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis by Plumlee, Courtney R., Duffy, Fergal J., Gern, Benjamin H., Delahaye, Jared L., Cohen, Sara B., Stoltzfus, Caleb R., Rustad, Tige R., Hansen, Scott G., Axthelm, Michael K., Picker, Louis J., Aitchison, John D., Sherman, David R., Ganusov, Vitaly V., Gerner, Michael Y., Zak, Daniel E., Urdahl, Kevin B.

“…Tuberculosis (TB) is a heterogeneous disease manifesting in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). Unlike human…”
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Hypoxia: a window into Mycobacterium tuberculosis latency by Rustad, Tige R, Sherrid, Ashley M, Minch, Kyle J, Sherman, David R

“…Tuberculosis is a massive public health problem on a global scale and the success of Mycobacterium tuberculosis is linked to its ability to persist within…”
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Characterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosis by Sherrid, Ashley M, Rustad, Tige R, Cangelosi, Gerard A, Sherman, David R

“…Mycobacterium tuberculosis (MTB) enters a non-replicating state when exposed to low oxygen tension, a condition the bacillus encounters in granulomas during…”
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Global analysis of mRNA stability in Mycobacterium tuberculosis by Rustad, Tige R, Minch, Kyle J, Brabant, William, Winkler, Jessica K, Reiss, David J, Baliga, Nitin S, Sherman, David R

“…Mycobacterium tuberculosis (MTB) is a highly successful pathogen that infects over a billion people. As with most organisms, MTB adapts to stress by modifying…”
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Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase by Hatzios, Stavroula K, Baer, Christina E, Rustad, Tige R, Siegrist, M Sloan, Pang, Jennifer M, Ortega, Corrie, Alber, Tom, Grundner, Christoph, Sherman, David R, Bertozzi, Carolyn R

“…Bacteria are able to adapt to dramatically different microenvironments, but in many organisms, the signaling pathways, transcriptional programs, and downstream…”
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ODELAM, rapid sequence-independent detection of drug resistance in isolates of Mycobacterium tuberculosis by Herricks, Thurston, Donczew, Magdalena, Mast, Fred D, Rustad, Tige, Morrison, Robert, Sterling, Timothy R, Sherman, David R, Aitchison, John D

“…Antimicrobial-resistant (Mtb) causes over 200,000 deaths each year. Current assays of antimicrobial resistance need knowledge of mutations that confer drug…”
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Mycobacterium tuberculosis Ser/Thr protein kinase B mediates an oxygen-dependent replication switch by Ortega, Corrie, Liao, Reiling, Anderson, Lindsey N, Rustad, Tige, Ollodart, Anja R, Wright, Aaron T, Sherman, David R, Grundner, Christoph

“…The majority of Mycobacterium tuberculosis (Mtb) infections are clinically latent, characterized by drug tolerance and little or no bacterial replication. Low…”
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A high-resolution network model for global gene regulation in Mycobacterium tuberculosis by Peterson, Eliza J R, Reiss, David J, Turkarslan, Serdar, Minch, Kyle J, Rustad, Tige, Plaisier, Christopher L, Longabaugh, William J R, Sherman, David R, Baliga, Nitin S

“…The resilience of Mycobacterium tuberculosis (MTB) is largely due to its ability to effectively counteract and even take advantage of the hostile environments…”
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Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose by Boot, Maikel, van Winden, Vincent J C, Sparrius, Marion, van de Weerd, Robert, Speer, Alexander, Ummels, Roy, Rustad, Tige, Sherman, David R, Bitter, Wilbert

“…The cell envelope of mycobacteria is a highly unique and complex structure that is functionally equivalent to that of Gram-negative bacteria to protect the…”
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Mapping and manipulating the Mycobacterium tuberculosis transcriptome using a transcription factor overexpression-derived regulatory network by Rustad, Tige R, Minch, Kyle J, Ma, Shuyi, Winkler, Jessica K, Hobbs, Samuel, Hickey, Mark, Brabant, William, Turkarslan, Serdar, Price, Nathan D, Baliga, Nitin S, Sherman, David R

“…Mycobacterium tuberculosis senses and responds to the shifting and hostile landscape of the host. To characterize the underlying intertwined gene regulatory…”
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Mycobacterium tuberculosis growth following aerobic expression of the DosR regulon by Minch, Kyle, Rustad, Tige, Sherman, David R

“…The Mycobacterium tuberculosis regulator DosR is induced by multiple stimuli including hypoxia, nitric oxide and redox stress. Overlap of these stimuli with…”
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Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis by Ma, Shuyi, Morrison, Robert, Hobbs, Samuel J., Soni, Vijay, Farrow-Johnson, Jessica, Frando, Andrew, Fleck, Neil, Grundner, Christoph, Rhee, Kyu Y., Rustad, Tige R., Sherman, David R.

“…Transposon-based strategies provide a powerful and unbiased way to study the bacterial stress response 1 – 8 , but these approaches cannot fully capture the…”
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Hypoxia induces an immunodominant target of tuberculosis specific T cells absent from common BCG vaccines by Gideon, Hannah Priyadarshini, Wilkinson, Katalin Andrea, Rustad, Tige R, Oni, Tolu, Guio, Heinner, Kozak, Robert Andrew, Sherman, David R, Meintjes, Graeme, Behr, Marcel A, Vordermeier, Hans Martin, Young, Douglas Brownlee, Wilkinson, Robert John

“…M. tuberculosis (MTB) species-specific antigenic determinants of the human T cell response are important for immunodiagnosis and vaccination. As hypoxia is a…”
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Bioinformatic and empirical analysis of novel hypoxia-inducible targets of the human antituberculosis T cell response by Gideon, Hannah P, Wilkinson, Katalin A, Rustad, Tige R, Oni, Tolu, Guio, Heinner, Sherman, David R, Vordermeier, H Martin, Robertson, Brian D, Young, Douglas B, Wilkinson, Robert J

“…We analyzed whole genome-based transcriptional profiles of Mycobacterium tuberculosis subjected to prolonged hypoxia to guide the discovery of novel potential…”
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A comprehensive map of genome-wide gene regulation in Mycobacterium tuberculosis by Turkarslan, Serdar, Peterson, Eliza J R, Rustad, Tige R, Minch, Kyle J, Reiss, David J, Morrison, Robert, Ma, Shuyi, Price, Nathan D, Sherman, David R, Baliga, Nitin S

“…Mycobacterium tuberculosis (MTB) is a pathogenic bacterium responsible for 12 million active cases of tuberculosis (TB) worldwide. The complexity and critical…”
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Isolation of mycobacterial RNA by Rustad, Tige R, Roberts, David M, Liao, Reiling P, Sherman, David R

“…This chapter describes two protocols for isolating total RNA from mycobacteria: one for extraction from in vitro cultures and one for extraction from in vivo…”
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Genes Required for Intrinsic Multidrug Resistance in Mycobacterium avium by PHILALAY, Julie S, PALERMO, Christine O, HAUGE, Kirsten A, RUSTAD, Tige R, CANGELOSI, Gerard A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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