Search Results - "Russo, Hana M"
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K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling
Published in The Journal of immunology (1950) (15-04-2015)“…Perturbation of intracellular ion homeostasis is a major cellular stress signal for activation of NLRP3 inflammasome signaling that results in…”
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Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling
Published in The Journal of biological chemistry (14-08-2015)“…We recently described the induction of noncanonical IL-1β processing via caspase-8 recruited to ripoptosome signaling platforms in myeloid leukocytes. Here, we…”
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NLRP3 inflammasome signaling is activated by low-level lysosome disruption but inhibited by extensive lysosome disruption: roles for K+ efflux and Ca2+ influx
Published in American Journal of Physiology: Cell Physiology (01-07-2016)“…Nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domain-containing 3 (NLRP3) is a cytosolic protein that nucleates assembly of…”
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Monocyte Chemoattractant Protein-1 Deficiency Protects Against Visceral Fat–Induced Atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (01-06-2010)“…OBJECTIVE—To determine the role of monocyte chemoattractant protein-1 (Mcp-1) on the progression of visceral fat–induced atherosclerosis. METHODS AND…”
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Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides
Published in The Journal of immunology (1950) (15-08-2016)“…Canonical inflammasome activation induces a caspase-1/gasdermin D (Gsdmd)-dependent lytic cell death called pyroptosis that promotes antimicrobial host defense…”
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P-Selectin Glycoprotein Ligand-1 Regulates Adhesive Properties of the Endothelium and Leukocyte Trafficking Into Adipose Tissue
Published in Circulation research (06-08-2010)“…RATIONALEAdhesive interactions between endothelial cells and leukocytes affect leukocyte trafficking in adipose tissue. The role of P-selectin glycoprotein…”
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Atherosclerosis and leukocyte–endothelial adhesive interactions are increased following acute myocardial infarction in apolipoprotein E deficient mice
Published in Atherosclerosis (01-10-2010)“…Abstract Objective To determine the effect of myocardial infarction (MI) on progression of atherosclerosis in apolipoprotein E deficient ( ApoE−/− ) mice…”
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K+ efflux agonists induce NLRP3 inflammasome activation independently of Ca2+ signaling1
Published in The Journal of immunology (1950) (11-03-2015)“…Perturbation of intracellular ion homeostasis is a major cellular stress signal for activation of NLRP3 inflammasome signaling that results in caspase-1…”
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Mcp-1 Deficiency Protects Against Visceral Fat-induced Atherosclerosis
Published in Arteriosclerosis, thrombosis, and vascular biology (18-03-2010)Get full text
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