Search Results - "Russell. L. Carr"

Effect of Developmental Exposure to Chlorpyrifos on the Expression of Neurotrophin Growth Factors and Cell-Specific Markers in Neonatal Rat Brain by Betancourt, Angela M., Burgess, Shane C., Carr, Russell L.

“…Chlorpyrifos (CPS), a known neurotoxicant, is a widely used agricultural organophosphorus insecticide. The effects of postnatal exposure to CPS on the…”
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Alteration of Neurotrophins in the Hippocampus and Cerebral Cortex of Young Rats Exposed to Chlorpyrifos and Methyl Parathion by Betancourt, Angela M., Filipov, Nikolay M., Carr, Russell L.

“…Exposure to either chlorpyrifos (CPS) or methyl parathion (MPS) results in the inhibition of acetylcholinesterase and leads to altered neuronal activity which…”
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Adolescent rat social play: Amygdalar proteomic and transcriptomic data by Alugubelly, Navatha, Mohammed, Afzaal N., Edelmann, Mariola J., Nanduri, Bindu, Sayed, Mohammed, Park, Juw Won, Carr, Russell L.

“…This data article contains the proteomic and transcriptomic data of the amygdala of adolescent rats involved in social play compared to non-behavioural…”
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Species Differences in Paraoxonase Mediated Hydrolysis of Several Organophosphorus Insecticide Metabolites by Carr, Russell L., Dail, Mary Beth, Chambers, Howard W., Chambers, Janice E.

“…Paraoxonase (PON1) is a calcium dependent enzyme that is capable of hydrolyzing organophosphate anticholinesterases. PON1 activity is present in most mammals…”
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Persistent proteomic changes in glutamatergic and GABAergic signaling in the amygdala of adolescent rats exposed to chlorpyrifos as juveniles by Alugubelly, Navatha, Mohammed, Afzaal N., Carr, Russell L.

“…•Juvenile chlorpyrifos exposure induced persistent changes in the amygdala proteome.•These changes occurred in proteins related to GABA and glutamate…”
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Short-term behavioral and histological findings following a single concussive and repeated subconcussive brain injury in a rodent model by Clay, Anna Marie, Carr, Russell L, DuBien, Janice L, To, Filip

“…It is unclear of the correlation between a mild traumatic brain injury (mTBI) and repeated subconcussive (RSC) impacts with respect to injury biomechanics…”
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Dopaminergic toxicity of the herbicide atrazine in rat striatal slices by Filipov, Nikolay M, Stewart, Molly A, Carr, Russell L, Sistrunk, Shannon C

“…Abstract A possible link between Parkinson's disease and pesticide exposure has been suggested, and recently it was shown that the herbicide atrazine (ATR)…”
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In vitro age-related differences in rats to organophosphates by Meek, Edward C., Carr, Russell L., Chambers, Janice E.

“…The mechanism of toxic action for organophosphates (OPs) is the persistent inhibition of acetylcholinesterase (AChE) resulting in accumulation of acetylcholine…”
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Proteomic and transcriptional profiling of rat amygdala following social play by Alugubelly, Navatha, Mohammad, Afzaal N., Edelmann, Mariola J., Nanduri, Bindu, Sayed, Mohammed, Park, Juw Won, Carr, Russell L.

“…Social play is the most characteristic form of social interaction which is necessary for adolescents to develop proper cognitive, emotional, and social…”
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Cnr1−/− has minimal impact on chlorpyrifos-mediated effects in the mouse endocannabinoid system, but it does alter lipopolysaccharide-induced cytokine levels in splenocytes by Szafran, Brittany N., Nichols, James, Nicaise, Ashleigh, Borazjani, Abdolsamad, Carr, Russell L., Wilson, Juliet R., Ross, Matthew K., Kaplan, Barbara L.F.

“…Chlorpyrifos (CPF) is an organophosphate pesticide that can inhibit endocannabinoid (eCB) metabolizing enzymes in animal models at levels that do not…”
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Inhibition of fatty acid amide hydrolase by chlorpyrifos in juvenile rats results in altered exploratory and social behavior as adolescents by Carr, Russell L., Alugubelly, Navatha, de Leon, Kathryne, Loyant, Louise, Mohammed, Afzaal N., Patterson, M. Elizabeth, Ross, Matthew K., Rowbotham, Nicole E.

“…•Chlorpyrifos (CPF) is an organophosphorus insecticide and suspected developmental neurotoxicant.•Repeated exposure of juvenile rats to CPF increased…”
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The mechanistic basis for the toxicity difference between juvenile rats and mice following exposure to the agricultural insecticide chlorpyrifos by Sette, Katelyn N., Alugubelly, Navatha, Glenn, Lauren B., Guo-Ross, Shirley X., Parkes, M. Katherine, Wilson, Juliet R., Seay, Caitlin N., Carr, Russell L.

“…At high exposure levels, organophosphorus insecticides (OPs) exert their toxicity in mammals through the inhibition of brain acetylcholinesterase (AChE)…”
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Effects of Chlorpyrifos on Serine Hydrolase Activities, Lipid Mediators, and Immune Responses in Lungs of Neonatal and Adult Mice by Szafran, Brittany N, Borazjani, Abdolsamad, Seay, Caitlin N, Carr, Russell L, Lehner, Richard, Kaplan, Barbara L. F, Ross, Matthew K

“…Chlorpyrifos (CPF) is an organophosphate (OP) pesticide that causes acute toxicity by inhibiting acetylcholinesterase (AChE) in the nervous system. However,…”
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Comparison of inhibition kinetics of several organophosphates, including some nerve agent surrogates, using human erythrocyte and rat and mouse brain acetylcholinesterase by Coban, Alper, Carr, Russell L., Chambers, Howard W., Willeford, Kenneth O., Chambers, Janice E.

“…•Inhibition kinetic assays were conducted with several highly relevant surrogates for sarin, VX and cyclosarin and insecticidal organophosphates in rat brain,…”
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Effect of repeated juvenile exposure to Δ9‑tetrahydrocannabinol on anxiety-related behavior and social interactions in adolescent rats by Mohammed, Afzaal N., Alugubelly, Navatha, Kaplan, Barbara L., Carr, Russell L.

“…The gestational and adolescent periods are critically important for brain development and exposure to Δ9‑tetrahydrocannabinol (Δ9-THC) during these periods…”
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Effect of Developmental Chlorpyrifos Exposure, on Endocannabinoid Metabolizing Enzymes, in the Brain of Juvenile Rats by Carr, Russell L., Borazjani, Abdolsamad, Ross, Matthew K.

“…The endogenous cannabinoids 2-arachidonoylglycerol (2-AG) and arachidonoyl ethanolamide (AEA or anandamide) play vital roles during nervous system development…”
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Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition by Carr, Russell L., Graves, Casey A., Mangum, Lee C., Nail, Carole A., Ross, Matthew K.

“…•Repeated developmental chlorpyrifos exposure alters brain endocannabinoid signaling.•Low levels of chlorpyrifos did not alter monoacylglycerol lipase activity…”
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Short-term behavioral and histological changes in a rodent model of mild traumatic brain injury by Clay, Anna Marie, Carr, Russell L, Dubien, Janice, To, Filip

“…An in-house developed weight drop injury (WDI) device is a recently described animal model of traumatic brain injury (TBI) that was designed to produce a…”
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Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development by Carr, Russell L., Armstrong, Nathan H., Buchanan, Alenda T., Eells, Jeffrey B., Mohammed, Afzaal N., Ross, Matthew K., Nail, Carole A.

“…•Repeated developmental chlorpyrifos exposure alters brain endocannabinoid signaling.•Preweanling exposure to chlorpyrifos inhibits FAAH and increases AEA,…”
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Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure by Carr, Russell L, Adams, Ashley L, Kepler, Darin R, Ward, Antonio B, Ross, Matthew K

“…The endogenous cannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) play vital roles during nervous system development. The degradation of 2-AG and…”
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