Search Results - "Russell McEvoy, Gaylene M."

Dynamics of capillary blood flow responses to acute local changes in oxygen and carbon dioxide concentrations by Russell McEvoy, Gaylene M, Wells, Brenda N, Kiley, Meghan E, Kaur, Kanika K, Fraser, Graham M

“…We aimed to quantify the magnitude and time transients of capillary blood flow responses to acute changes in local oxygen concentration ([O ]), and carbon…”
Get full text

Fixing skeletal muscle PO2 eliminates hyperinsulinemic microvascular blood flow response by Wells, Brenda N., Russell McEvoy, Gaylene M., Shogan, Hamza, Kiley, Meghan E., Fraser, Graham M.

“…Objective To determine if insulin‐mediated hyperemia is partially dependent on local muscle oxygen concentration. Methods Sprague–Dawley rats were…”
Get full text

Development and validation of a novel microfluidic device for the manipulation of skeletal muscle microvascular blood flow in vivo by Russell McEvoy, Gaylene M., Shogan, Hamza, Sové, Richard J., Fraser, Graham M.

“…Objective To develop and validate a novel liquid microfluidic approach to deliver drugs to microscale regions of tissue while simultaneously allowing for…”
Get full text

Clamping Skeletal Muscle PO 2 Eliminates Hyperinsulinemic Microvascular Blood Flow Response by Wells, Brenda N, Russell McEvoy, Gaylene M, Shogan, Hamza, Kiley, Meghan E, Fraser, Graham M

“…To determine if insulin mediated hyperemia is partially dependent on local muscle oxygen concentration. The blood flow responses to insulin are partially…”
Get full text

Fixing skeletal muscle PO 2 eliminates hyperinsulinemic microvascular blood flow response by Wells, Brenda N, Russell McEvoy, Gaylene M, Shogan, Hamza, Kiley, Meghan E, Fraser, Graham M

“…To determine if insulin-mediated hyperemia is partially dependent on local muscle oxygen concentration. Sprague-Dawley rats were anesthetized, and the extensor…”
Get full text

Development of thin-film micro-outlet devices for spatially constraining local O 2 perturbations to capillaries by Kiley, Meghan E, Smith, Reilly H, Russell McEvoy, Gaylene M, Wells, Brenda N, Fraser, Graham M

“…To develop and validate thin film micro-outlet devices to study microvascular blood flow responses to localized changes in skeletal muscle oxygen concentration…”
Get full text

Microvascular Blood Flow Response to Hyperinsulinemic‐Euglycemic Clamp in Zucker Diabetic Sprague Dawley Rat Model of Type 2 Diabetes by Russell McEvoy, Gaylene M., Wells, Brenda N., Shogan, Hamza, Kiley, Meghan E., McCarthy, Meaghan A., Fraser, Graham M.

“…Objective Quantify and characterize the skeletal muscle microvascular blood flow in Zucker Diabetic Sprague Dawley (ZDSD) rat model of T2D at rest and during a…”
Get full text

Computational Model to Predict Tissue Concentration of Drugs Delivered via Intravital Fluid Exchange Devices by Sové, Richard J., Russell McEvoy, Gaylene M., Fraser, Graham M.

“…Abstract only The microcirculation is capable of precise blood flow regulation enabling fine control over the distribution of oxygen (O 2 ) to tissues in the…”
Get full text

Clamping Skeletal Muscle PO2 Eliminates Hyperinsulinemic Microvascular Blood Flow Response by Wells, Brenda N., Russell McEvoy, Gaylene M., Shogan, Hamza, Kiley, Meghan E., Fraser, Graham M.

“…Objective To determine if insulin mediated hyperemia is partially dependent on local muscle oxygen concentration. Hypothesis The blood flow responses to…”
Get full text

Development of thin‐film micro‐outlet devices for spatially constraining local O2 perturbations to capillaries by Kiley, Meghan E., Smith, Reilly H., Russell McEvoy, Gaylene M., Wells, Brenda N., Fraser, Graham M.

“…Objective To develop and validate thin film micro‐outlet devices to study microvascular blood flow responses to localized changes in skeletal muscle oxygen…”
Get full text

Microvascular Blood Flow Response to Hyperinsulinemia in Type 2 Diabetic Rats by Shogan, Hamza, Russell McEvoy, Gaylene M, Fraser, Graham M

“…Objective Chronic hyperglycemia is a defining feature of type 2 diabetes (T2D) that has been implicated in impaired microvascular structure and function. We…”
Get full text

Application of a Novel Microfluidic Device for Studying Microvascular Blood Flow Regulation In Vivo by Russell McEvoy, Gaylene M, Shogan, Hamza, Fraser, Graham M

“…Objective Validate the efficacy of a novel liquid microfluidic device (LMFD) to manipulate microvascular blood flow by maintaining a fixed solute…”
Get full text