Search Results - "Russell, DW"

THE ENZYMES, REGULATION, AND GENETICS OF BILE ACID SYNTHESIS by Russell, David W

“…The synthesis and excretion of bile acids comprise the major pathway of cholesterol catabolism in mammals. Synthesis provides a direct means of converting…”
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Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung by Genschmer, Kristopher R., Russell, Derek W., Lal, Charitharth, Szul, Tomasz, Bratcher, Preston E., Noerager, Brett D., Abdul Roda, Mojtaba, Xu, Xin, Rezonzew, Gabriel, Viera, Liliana, Dobosh, Brian S., Margaroli, Camilla, Abdalla, Tarek H., King, Robert W., McNicholas, Carmel M., Wells, J. Michael, Dransfield, Mark T., Tirouvanziam, Rabindra, Gaggar, Amit, Blalock, J. Edwin

“…Here, we describe a novel pathogenic entity, the activated PMN (polymorphonuclear leukocyte, i.e., neutrophil)-derived exosome. These CD63+/CD66b+ nanovesicles…”
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Clinical importance of the cytochromes P450 by Nebert, Daniel W, Russell, David W

“…The human cytochrome P450 (CYP) superfamily comprises 57 genes. These genes code for enzymes that can have a role in: metabolism of drugs, foreign chemicals,…”
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In Search of Underlying Dimensions: The Use (and Abuse) of Factor Analysis in Personality and Social Psychology Bulletin by Russell, Daniel W.

“…An examination of the use of exploratory and confirmatory factor analysis by researchers publishing in Personality and Social Psychology Bulletin over the…”
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Transplanted bone marrow regenerates liver by cell fusion by Russell, David W, Vassilopoulos, George, Wang, Pei-Rong

“…Results from several experimental systems suggest that cells from one tissue type can form other tissue types after transplantation. This could be due to the…”
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Adult Attachment, Social Self-Efficacy, Self-Disclosure, Loneliness, and Subsequent Depression for Freshman College Students: A Longitudinal Study by Wei, Meifen, Russell, Daniel W, Zakalik, Robyn A

“…This longitudinal study examined whether social self-efficacy and self-disclosure serve as mediators between attachment and feelings of loneliness and…”
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Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions by Cheng, Jeffrey B, Russell, David W

“…The conversion of fatty acids to fatty alcohols is required for the synthesis of wax monoesters and ether lipids. The mammalian enzymes that synthesize fatty…”
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A comprehensive classification system for lipids by Fahy, Eoin, Subramaniam, Shankar, Brown, H Alex, Glass, Christopher K, Merrill, Jr, Alfred H, Murphy, Robert C, Raetz, Christian R H, Russell, David W, Seyama, Yousuke, Shaw, Walter, Shimizu, Takao, Spener, Friedrich, van Meer, Gerrit, VanNieuwenhze, Michael S, White, Stephen H, Witztum, Joseph L, Dennis, Edward A

“…Lipids are produced, transported, and recognized by the concerted actions of numerous enzymes, binding proteins, and receptors. A comprehensive analysis of…”
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Systemic delivery of genes to striated muscles using adeno-associated viral vectors by Chamberlain, Jeffrey S, Gregorevic, Paul, Blankinship, Michael J, Allen, James M, Crawford, Robert W, Meuse, Leonard, Miller, Daniel G, Russell, David W

“…A major obstacle limiting gene therapy for diseases of the heart and skeletal muscles is an inability to deliver genes systemically to muscles of an adult…”
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De-orphanization of Cytochrome P450 2R1: A Microsomal Vitamin D 25-Hydroxylase by Cheng, J B, Motola, D L, Mangelsdorf, D J, Russell, D W

“…The conversion of vitamin D into an active ligand for the vitamin D receptor requires 25-hydroxylation in the liver and 1 alpha -hydroxylation in the kidney…”
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Genetic Evidence That the Human CYP2R1 Enzyme Is a Key Vitamin D 25-Hydroxylase by Cheng, Jeffrey B., Levine, Michael A., Bell, Norman H., Mangelsdorf, David J., Russell, David W., Wilson, Jean D.

“…The synthesis of bioactive vitamin D requires hydroxylation at the 1α and 25 positions by cytochrome P450 enzymes in the kidney and liver, respectively. The…”
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Oxysterol biosynthetic enzymes by Russell, David W

“…Oxysterols, herein defined as derivatives of cholesterol with a hydroxyl group on the side chain, play several roles in lipid metabolism. Members of this class…”
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Aerobic exercise, but not flexibility/resistance exercise, reduces serum IL-18, CRP, and IL-6 independent of β-blockers, BMI, and psychosocial factors in older adults by Kohut, M.L., McCann, D.A., Russell, D.W., Konopka, D.N., Cunnick, J.E., Franke, W.D., Castillo, M.C., Reighard, A.E., Vanderah, E.

“…Increased serum levels of inflammatory mediators have been associated with numerous disease states including atherosclerosis, Type II diabetes, hypertension,…”
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Adeno-associated virus vectors integrate at chromosome breakage sites by Russell, David W, Miller, Daniel G, Petek, Lisa M

“…Adeno-associated virus (AAV) vectors transduce cells by multiple pathways, including integration at nonhomologous chromosomal locations by an unknown…”
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Brain Cholesterol Turnover Required for Geranylgeraniol Production and Learning in Mice by Kotti, Tiina J., Ramirez, Denise M. O., Pfeiffer, Brad E., Huber, Kimberly M., Russell, David W.

“…The mevalonate pathway produces cholesterol and nonsterol isoprenoids, such as geranylgeraniol. In the brain, a fraction of cholesterol is metabolized in…”
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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice by Li-Hawkins, J, Gafvels, M, Olin, M, Lund, EG, Andersson, U, Schuster, G, Bjorkhem, I, Russell, DW, Eggertsen, G

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UCLA Loneliness Scale (Version 3): reliability, validity, and factor structure by Russell, D W

“…In this article I evaluated the psychometric properties of the UCLA Loneliness Scale (Version 3). Using data from prior studies of college students, nurses,…”
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Foamy Virus Vector Integration Sites in Normal Human Cells by Trobridge, Grant D., Miller, Daniel G., Jacobs, Michael A., Allen, James M., Kiem, Hans-Peter, Kaul, Rajinder, Russell, David W.

“…Foamy viruses (FVs) or spumaviruses are retroviruses that have been developed as vectors, but their integration patterns have not been described. We have…”
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Knockout of the Cholesterol 24-Hydroxylase Gene in Mice Reveals a Brain-specific Mechanism of Cholesterol Turnover by Lund, Erik G, Xie, Chonglun, Kotti, Tiina, Turley, Stephen D, Dietschy, John M, Russell, David W

“…Most cholesterol turnover takes place in the liver and involves the conversion of cholesterol into soluble and readily excreted bile acids. The synthesis of…”
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Gene Targeting with Viral Vectors by Hendrie, Paul C, Russell, David W

“…Genetic manipulation of cells for scientific and therapeutic goals can be achieved by both gene-addition and gene-targeting methods. Gene targeting precisely…”
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