Search Results - "Russano, Marco"
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Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples
Published in Journal of experimental & clinical cancer research (27-05-2020)“…In a large number of cancer types, treatment selection depends on the presence of specific tumor biomarkers. Due to the dynamic nature of cancer, very often…”
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2
Another side of the association between body mass index (BMI) and clinical outcomes of cancer patients receiving programmed cell death protein-1 (PD-1)/ Programmed cell death-ligand 1 (PD-L1) checkpoint inhibitors: A multicentre analysis of immune-related adverse events
Published in European journal of cancer (1990) (01-03-2020)“…Several studies have found an association between higher body mass index (BMI) and improved clinical outcomes in cancer patients receiving programmed cell…”
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A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable
Published in Journal for immunotherapy of cancer (27-02-2019)“…Recent evidence suggested a potential correlation between overweight and the efficacy of immune checkpoint inhibitors (ICIs) in cancer patients. We conducted a…”
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Correlations Between the Immune-related Adverse Events Spectrum and Efficacy of Anti-PD1 Immunotherapy in NSCLC Patients
Published in Clinical lung cancer (01-07-2019)“…Immune-related adverse events (irAEs) developed during immunotherapy with anti-PD-1 agents, could be a predictive surrogate marker of clinical benefit in…”
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Integrated analysis of concomitant medications and oncological outcomes from PD-1/PD-L1 checkpoint inhibitors in clinical practice
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundConcomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint…”
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Prognostic and predictive factors in pancreatic cancer
Published in Oncotarget (10-03-2020)“…Pancreatic cancer is one of the leading causes of cancer death worldwide. Its high mortality rate has remained unchanged for years. Radiotherapy and surgery…”
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Immunotherapy for colorectal cancer: where are we heading?
Published in Expert opinion on biological therapy (03-06-2017)“…In the last few years, significant advances in molecular biology have provided new therapeutic options for colorectal cancer (CRC). The development of new…”
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Natural History of Non-Small-Cell Lung Cancer with Bone Metastases
Published in Scientific reports (22-12-2015)“…We conducted a large, multicenter, retrospective survey aimed to explore the impact of tumor bone involvement in Non-Small Cell Lung Cancer.Data on…”
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Immune-related Adverse Events of Pembrolizumab in a Large Real-world Cohort of Patients With NSCLC With a PD-L1 Expression ≥ 50% and Their Relationship With Clinical Outcomes
Published in Clinical lung cancer (01-11-2020)“…The role of immune-related adverse events (irAEs), as a surrogate predictor of the efficacy of checkpoint inhibitors, has not yet been described in the setting…”
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Post-progression outcomes of NSCLC patients with PD-L1 expression ≥ 50% receiving first-line single-agent pembrolizumab in a large multicentre real-world study
Published in European journal of cancer (1990) (01-05-2021)“…Treatment sequencing with first-line immunotherapy, followed by second-line chemotherapy, is still a viable option for NSCLC patients with PD-L1 expression…”
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Change from lung adenocarcinoma to small cell lung cancer as a mechanism of resistance to afatinib
Published in Oncotarget (29-08-2017)“…We report the case of a patient affected by advanced EGFR mutation-positive lung who experienced resistance to therapy during treatment with Afatinib through…”
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Immunotherapy for Metastatic Non-Small Cell Lung Cancer: Therapeutic Advances and Biomarkers
Published in Current oncology (Toronto) (01-02-2023)“…Immunotherapy has revolutionized the treatment paradigm of non-small cell lung cancer and improved patients' prognosis. Immune checkpoint inhibitors have…”
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Circulating receptor activator of nuclear factor kappa-B ligand (RANKL) levels predict response to immune checkpoint inhibitors in advanced non-small cell lung cancer (NSCLC)
Published in Journal for immunotherapy of cancer (01-06-2024)“…BackgroundReceptor activator of nuclear factor kappa-B ligand (RANKL) can directly promote tumor growth and indirectly support tumor immune evasion by altering…”
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Response to: Successful afatinib rechallenge in a patient with non‐small cell lung cancer harboring EGFR G719C and S768I mutations
Published in Thoracic cancer (01-06-2021)“…The genetic landscape of nonsquamous non‐small cell lung cancer (NSCLC) includes specific mutations involving primarily epidermal growth factor receptor…”
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Treatment of Metastatic Colorectal Cancer Patients ≥75 Years Old in Clinical Practice: A Multicenter Analysis
Published in PloS one (21-07-2016)“…Colorectal cancer patients have a median age of incidence >65years although they are largely under-represented in phase-III trials. This large population…”
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Cabozantinib and apixaban: an hitherto unreported interaction
Published in Experimental hematology & oncology (11-09-2019)“…The use of direct oral anticoagulant in cancer patients is an emerging issue, which seems to be an alternative to low molecular weight heparin. Every year…”
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Correction to: Liquid biopsy and tumor heterogeneity in metastatic solid tumors: the potentiality of blood samples
Published in Journal of experimental & clinical cancer research (24-06-2020)“…An amendment to this paper has been published and can be accessed via the original article…”
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Steroid-refractory immune related hepatitis may hide viral re-activation
Published in Future science OA (01-10-2020)“…Cancer immunotherapy has become a stronghold in modern oncology. Immune checkpoint inhibitors, in particular anti-PD-1 and anti-PD-L1 antibodies, are approved…”
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"Impact of Smoking Cessation Treatment" on Lung Function and Response Rate in EGFR Mutated Patients: A Short-Term Cohort Study
Published in Recent patents on anti-cancer drug discovery (01-01-2015)“…Erlotinib is a validated drug "for the treatment of patients affected by advanced unresectable non small cell lung cancer (NSCLC) with EGFR mutations". We want…”
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Detection of novel driver mutations in liquid biopsy: case report of a RET-positive lung adenocarcinoma treated with pralsetinib.
Published in Recenti progressi in medicina (01-01-2021)“…Advances in cancer biology research led to the identification of new molecular drivers in non-small cell lung cancer. These alterations should be searched…”
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