Search Results - "Russ, S."

Exosome-Mediated miR-29 Transfer Reduces Muscle Atrophy and Kidney Fibrosis in Mice by Wang, Haidong, Wang, Bin, Zhang, Aiqing, Hassounah, Faten, Seow, Yiqi, Wood, Matthew, Ma, Fuying, Klein, Janet D., Price, S. Russ, Wang, Xiaonan H.

“…Our previous study showed that miR-29 attenuates muscle wasting in chronic kidney disease. Other studies found that miR-29 has anti-fibrosis activity. We…”
Get full text

Pathophysiological mechanisms leading to muscle loss in chronic kidney disease by Wang, Xiaonan H., Mitch, William E., Price, S. Russ

“…Loss of muscle proteins is a deleterious consequence of chronic kidney disease (CKD) that causes a decrease in muscle strength and function, and can lead to a…”
Get full text

The Effect of a Golden Hour Policy on the Morbidity and Mortality of Combat Casualties by Kotwal, Russ S, Howard, Jeffrey T, Orman, Jean A, Tarpey, Bruce W, Bailey, Jeffrey A, Champion, Howard R, Mabry, Robert L, Holcomb, John B, Gross, Kirby R

“…The term golden hour was coined to encourage urgency of trauma care. In 2009, Secretary of Defense Robert M. Gates mandated prehospital helicopter transport of…”
Get more information

MicroRNA-23a and MicroRNA-27a Mimic Exercise by Ameliorating CKD-Induced Muscle Atrophy by Wang, Bin, Zhang, Cong, Zhang, Aiqing, Cai, Hui, Price, S Russ, Wang, Xiaonan H

“…Muscle atrophy is a frequent complication of CKD, and exercise can attenuate the process. This study investigated the role of microRNA-23a (miR-23a) and…”
Get full text

Association of Prehospital Blood Product Transfusion During Medical Evacuation of Combat Casualties in Afghanistan With Acute and 30-Day Survival by Shackelford, Stacy A, del Junco, Deborah J, Powell-Dunford, Nicole, Mazuchowski, Edward L, Howard, Jeffrey T, Kotwal, Russ S, Gurney, Jennifer, Butler, Frank K, Gross, Kirby, Stockinger, Zsolt T

“…IMPORTANCE: Prehospital blood product transfusion in trauma care remains controversial due to poor-quality evidence and cost. Sequential expansion of blood…”
Get full text

miRNA‐23a/27a attenuates muscle atrophy and renal fibrosis through muscle‐kidney crosstalk by Zhang, Aiqing, Li, Min, Wang, Bin, Klein, Janet D., Price, S. Russ, Wang, Xiaonan H.

“…Background The treatment of muscle wasting is accompanied by benefits in other organs, possibly resulting from muscle–organ crosstalk. However, how the muscle…”
Get full text

Etiology of the Protein-Energy Wasting Syndrome in Chronic Kidney Disease: A Consensus Statement From the International Society of Renal Nutrition and Metabolism (ISRNM) by Carrero, Juan Jesús, PhD, Stenvinkel, Peter, MD, PhD, Cuppari, Lilian, PhD, Ikizler, T. Alp, MD, PhD, Kalantar-Zadeh, Kamyar, MD, PhD, Kaysen, George, MD, PhD, Mitch, William E., MD, PhD, Price, S. Russ, PhD, Wanner, Christoph, MD, PhD, Wang, Angela Y.M., MD, PhD, ter Wee, Pieter, MD, PhD, Franch, Harold A., MD

“…Protein-energy wasting (PEW), a term proposed by the International Society of Renal Nutrition and Metabolism (ISRNM), refers to the multiple nutritional and…”
Get full text

Use of Combat Casualty Care Data to Assess the US Military Trauma System During the Afghanistan and Iraq Conflicts, 2001-2017 by Howard, Jeffrey T, Kotwal, Russ S, Stern, Caryn A, Janak, Jud C, Mazuchowski, Edward L, Butler, Frank K, Stockinger, Zsolt T, Holcomb, Barbara R, Bono, Raquel C, Smith, David J

“…Although the Afghanistan and Iraq conflicts have the lowest US case-fatality rates in history, no comprehensive assessment of combat casualty care statistics,…”
Get more information

A New Dimension to the Mechanisms Causing Muscle Loss in CKD by Price, S Russ, Bailey, James L

Get full text

miR-182 attenuates atrophy-related gene expression by targeting FoxO3 in skeletal muscle by Hudson, Matthew B, Rahnert, Jill A, Zheng, Bin, Woodworth-Hobbs, Myra E, Franch, Harold A, Price, S Russ

“…Skeletal muscle atrophy occurs in response to a variety of conditions including chronic kidney disease, diabetes, cancer, and elevated glucocorticoids…”
Get more information

Going micro in CKD-related cachexia by Wang, Xiaonan H, Price, S Russ

Get full text

Reexamination of a Battlefield Trauma Golden Hour Policy by Howard, Jeffrey T, Kotwal, Russ S, Santos-Lazada, Alexis R, Martin, Matthew J, Stockinger, Zsolt T

“…Most combat casualties who die, do so in the prehospital setting. Efforts directed toward alleviating prehospital combat trauma death, known as killed in…”
Get full text

Calcineurin: A poorly understood regulator of muscle mass by Hudson, Matthew B., Price, S. Russ

“…This review will discuss the existing literature that has examined the role of calcineurin (CnA) in the regulation of skeletal muscle mass in conditions…”
Get full text

Muscle Atrophy in CKD: A Historical Perspective of Advancements in Its Understanding by Price, S. Russ, Mitch, William E., Garibotto, Giacomo

“…This perspective reviews the seminal clinical and experimental observations that led to today's current mechanistic model of muscle protein loss (wasting) in…”
Get full text

Palmitate-induced ER stress and inhibition of protein synthesis in cultured myotubes does not require Toll-like receptor 4 by Perry, Ben D, Rahnert, Jill A, Xie, Yang, Zheng, Bin, Woodworth-Hobbs, Myra E, Price, S Russ

“…Saturated fatty acids, such as palmitate, are elevated in metabolically dysfunctional conditions like type 2 diabetes mellitus. Palmitate has been shown to…”
Get full text

Organ Crosstalk Contributes to Muscle Wasting in Chronic Kidney Disease by Wang, Xiaonan H, Price, S Russ

“…Muscle wasting (ie, atrophy) is a serious consequence of chronic kidney disease (CKD) that reduces muscle strength and function. It reduces the quality of life…”
Get full text

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension by Landmesser, Ulf, Dikalov, Sergey, Price, S Russ, McCann, Louise, Fukai, Tohru, Holland, Steven M, Mitch, William E, Harrison, David G

“…Tetrahydrobiopterin is a critical cofactor for the NO synthases, and in its absence these enzymes become "uncoupled," producing reactive oxygen species (ROSs)…”
Get full text

Flash Flood Verification: Pondering Precipitation Proxies by Herman, Gregory R., Schumacher, Russ S.

“…Quantitative precipitation estimate (QPE) exceedances of numerous different heavy precipitation thresholds—including spatially varying average recurrence…”
Get full text

miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export by Hudson, Matthew B, Woodworth-Hobbs, Myra E, Zheng, Bin, Rahnert, Jill A, Blount, Mitsi A, Gooch, Jennifer L, Searles, Charles D, Price, S Russ

“…Skeletal muscle atrophy is prevalent in chronic diseases, and microRNAs (miRs) may play a key role in the wasting process. miR-23a was previously shown to…”
Get more information

THE 2015 PLAINS ELEVATED CONVECTION AT NIGHT FIELD PROJECT by Geerts, Bart, Parsons, David, Ziegler, Conrad L., Weckwerth, Tammy M., Biggerstaff, Michael I., Clark, Richard D., Coniglio, Michael C., Demoz, Belay B., Ferrare, Richard A., Gallus, William A., Haghi, Kevin, Hanesiak, John M., Klein, Petra M., Knupp, Kevin R., Kosiba, Karen, McFarquhar, Greg M., Moore, James A., Nehrir, Amin R., Parker, Matthew D., Pinto, James O., Rauber, Robert M., Schumacher, Russ S., Turner, David D., Wang, Qing, Wang, Xuguang, Wang, Zhien, Wurman, Joshua

“…The central Great Plains region in North America has a nocturnal maximum in warm-season precipitation. Much of this precipitation comes from organized…”
Get full text