Search Results - "Russ, Patricia K."
-
1
A magnetic bead-based method for concentrating DNA from human urine for downstream detection
Published in PloS one (08-07-2013)“…Due to the presence of PCR inhibitors, PCR cannot be used directly on most clinical samples, including human urine, without pre-treatment. A magnetic…”
Get full text
Journal Article -
2
Tuberculosis Biomarker Extraction and Isothermal Amplification in an Integrated Diagnostic Device
Published in PloS one (01-07-2015)“…In this study, we integrated magnetic bead-based sample preparation and isothermal loop mediated amplification (LAMP) of TB in a single tube. Surrogate sputum…”
Get full text
Journal Article -
3
Detection of respiratory syncytial virus using nanoparticle amplified immuno-polymerase chain reaction
Published in Analytical biochemistry (01-03-2011)“…In traditional immuno-polymerase chain reaction (immuno-PCR), a single antibody recognition event is associated with one to three DNA tags, which are…”
Get full text
Journal Article -
4
Bves modulates tight junction associated signaling
Published in PloS one (20-01-2011)“…Blood vessel epicardial substance (Bves) is a transmembrane adhesion protein that regulates tight junction (TJ) formation in a variety of epithelia. The role…”
Get full text
Journal Article -
5
Low-Resource Nucleic Acid Extraction Method Enabled by High-Gradient Magnetic Separation
Published in ACS applied materials & interfaces (18-03-2020)“…Nucleic acid-based diagnostic tests often require isolation and concentration of nucleic acids from biological samples. Commercial purification kits are…”
Get full text
Journal Article -
6
Correction to “Low-Resource Nucleic Acid Extraction Method Enabled by High-Gradient Magnetic Separation”
Published in ACS applied materials & interfaces (10-01-2024)Get full text
Journal Article -
7
Surface Engineering of Quantum Dots for In Vivo Vascular Imaging
Published in Bioconjugate chemistry (01-09-2007)“…Quantum dot−antibody bioconjugates (QD-mAb) were synthesized incorporating PEG cross-linkers and Fc-shielding mAb fragments to increase in vivo circulation…”
Get full text
Journal Article -
8
Development of a Low-Resource RNA Extraction Cassette Based on Surface Tension Valves
Published in ACS applied materials & interfaces (22-06-2011)“…Nucleic acid-based diagnostics are highly sensitive and specific, but are easily disrupted by the presence of interferents in biological samples. In a…”
Get full text
Journal Article -
9
Design and use of mouse control DNA for DNA biomarker extraction and PCR detection from urine: Application for transrenal Mycobacterium tuberculosis DNA detection
Published in Journal of microbiological methods (01-05-2017)“…Urine samples are increasingly used for diagnosing infections including Escherichia coli, Ebola virus, and Zika virus. However, extraction and concentration of…”
Get full text
Journal Article -
10
Inhibition of RhoA Signaling with Increased Bves in Trabecular Meshwork Cells
Published in Investigative ophthalmology & visual science (01-01-2010)“…Blood vessel epicardial substance (Bves) is a novel adhesion molecule that regulates tight junction (TJ) formation. TJs also modulate RhoA signaling, which has…”
Get full text
Journal Article -
11
A Prototype Biomarker Detector Combining Biomarker Extraction and Fixed Temperature PCR
Published in Journal of Laboratory Automation (01-08-2016)“…PCR is the most sensitive molecular diagnostic available for infectious diseases. The goal for low-resource settings is a simple, inexpensive instrument…”
Get full text
Journal Article -
12
Autonomous reovirus strain classification using filament-coupled antibodies
Published in Annals of biomedical engineering (01-11-2006)“…We previously described a filament-based antibody recognition assay (FARA) that generates ELISA-like sandwich structures immobilized on a filament. FARA allows…”
Get full text
Journal Article -
13
Detection of Respiratory Syncytial Virus Using Nanoparticle Amplified Immuno-PCR
Published in Analytical biochemistry (25-11-2010)“…In traditional immuno-PCR a single antibody recognition event is associated with one to three DNA tags, which are subsequently amplified by PCR. Here, we…”
Get full text
Journal Article -
14
Tuberculosis Biomarker Extraction and Isothermal Amplification in an Integrated Diagnostic Device: e0130260
Published in PloS one (01-07-2015)“…In this study, we integrated magnetic bead-based sample preparation and isothermal loop mediated amplification (LAMP) of TB in a single tube. Surrogate sputum…”
Get full text
Journal Article -
15
A Magnetic Bead-Based Method for Concentrating DNA from Human Urine for Downstream Detection. e68369
Published in PloS one (01-07-2013)“…Due to the presence of PCR inhibitors, PCR cannot be used directly on most clinical samples, including human urine, without pre-treatment. A magnetic…”
Get full text
Journal Article -
16
Partial characterization of the human retinal endothelial cell tight and adherens junction complexes
Published in Investigative ophthalmology & visual science (01-11-1998)“…In diabetic retinopathy and macular edema, the blood-retinal barrier fails to function properly, and there is transvascular leakage of proteins and solutes…”
Get full text
Journal Article -
17
Reduced expression of the adherens junction protein cadherin-5 in a diabetic retina
Published in American journal of ophthalmology (01-02-2000)“…PURPOSE: Transvascular leakage occurs in diabetic retinopathy. The tight junction proteins occludin and zonula occludens-1 (ZO-1) and adherens junction protein…”
Get full text
Journal Article