Search Results - "Rusnak, Milan"

Iron Deposition and Ferroptosis in the Spleen in a Murine Model of Acute Radiation Syndrome by Rittase, W. Bradley, Slaven, John E., Suzuki, Yuichiro J., Muir, Jeannie M., Lee, Sang-Ho, Rusnak, Milan, Brehm, Grace V., Bradfield, Dmitry T., Symes, Aviva J., Day, Regina M.

“…Total body irradiation (TBI) can result in death associated with hematopoietic insufficiency. Although radiation causes apoptosis of white blood cells, red…”
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Histone Deacetylase Inhibition Rescues Maternal Deprivation-Induced GABAergic Metaplasticity through Restoration of AKAP Signaling by Authement, Michael E., Kodangattil, Jayaraj N., Gouty, Shawn, Rusnak, Milan, Symes, Aviva J., Cox, Brian M., Nugent, Fereshteh S.

“…Adverse early-life experiences such as child neglect and abuse increase the risk of developing addiction and stress-related disorders through alterations in…”
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Transcriptomic Analysis of Mouse Brain After Traumatic Brain Injury Reveals That the Angiotensin Receptor Blocker Candesartan Acts Through Novel Pathways by Attilio, Peter J, Snapper, Dustin M, Rusnak, Milan, Isaac, Akira, Soltis, Anthony R, Wilkerson, Matthew D, Dalgard, Clifton L, Symes, Aviva J

“…Traumatic brain injury (TBI) results in complex pathological reactions, where the initial lesion is followed by secondary inflammation and edema. Our…”
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Modulation of the trafficking of the human serotonin transporter by human alpha-synuclein by Wersinger, Christophe, Rusnak, Milan, Sidhu, Anita

“…α‐Synuclein (α‐Syn), a protein primarily localized in the presynaptic compartment of neurons, is known to regulate dopaminergic neurotransmission by negatively…”
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Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades by Chen, Jun, Rusnak, Milan, Lombroso, Paul J., Sidhu, Anita

“…Although the mechanisms underlying striatal neurodegeneration are poorly understood, we have shown that striatal pathogenesis may be initiated by high synaptic…”
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D1 Dopamine Receptor Mediates Dopamine-induced Cytotoxicity via the ERK Signal Cascade by Chen, Jun, Rusnak, Milan, Luedtke, Robert R., Sidhu, Anita

“…Postsynaptic striatal neurodegeneration occurs through unknown mechanisms, but it is linked to high extracellular levels of synaptic dopamine…”
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Corticotropin-releasing hormone mRNA levels in response to chronic mild stress rise in male but not in female rats while tyrosine hydroxylase mRNA levels decrease in both sexes by Dunčko, Roman, Kiss, Alexander, Škultétyová, Ivana, Rusnák, Milan, Ježová, Daniela

“…Corticotropin-releasing hormone (CRH) and catecholamines are suggested to play a significant role in the pathophysiology of depression. In the present study we…”
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Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies by Moussa, Charbel E.-H., Rusnak, Milan, Hailu, Ayichew, Sidhu, Anita, Fricke, Stanley T.

“…Animal models treated with agricultural chemicals, such as rotenone, reproduce several degenerative features of human central nervous system (CNS) diseases…”
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8663 Sex differences in delayed fear incubation in mice by Littlepage-Saunders, Mydirah, Rusnak, Milan, Tsuda, Mumeko, John Wu, T

“…Abstract Disclosure: M. Littlepage-Saunders: None. M. Rusnak: None. M. Tsuda: None. T. Wu: None. Post-traumatic stress disorder (PTSD) has a lifetime…”
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Iron Deposition in the Spleen in a Murine Model of Acute Radiation Syndrome by Rittase, Bradley, Slaven, John E., Muir, Jeannie M., Lee, Sang‐Ho, Rusnak, Milan, Brehm, Grace, Symes, Aviva, Day, Regina

“…Total body radiation (TBI) can result in death associated with hematopoietic insufficiency. Although radiation causes apoptosis of white blood cells, red blood…”
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Alpha‐Synuclein induces hyperphosphorylation of Tau in the MPTP model of Parkinsonism by Duka, Tetyana, Rusnak, Milan, Drolet, Robert E., Duka, Valeriy, Wersinger, Christophe, Goudreau, John L., Sidhu, Anita

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Involvement of Lateral Habenula Dysfunction in Repetitive Mild Traumatic Brain Injury-Induced Motivational Deficits by Flerlage, William J, Langlois, Ludovic D, Rusnak, Milan, Simmons, Sarah C, Gouty, Shawn, Armstrong, Regina C, Cox, Brian M, Symes, Aviva J, Tsuda, Mumeko C, Nugent, Fereshteh S

“…Affective disorders including depression (characterized by reduced motivation, social withdrawal, and anhedonia), anxiety, and irritability are frequently…”
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Effect of novel stressors on gene expression of tyrosine hydroxylase and monoamine transporters in brainstem noradrenergic neurons of long-term repeatedly immobilized rats by Rusnák, Milan, Kvetňanský, Richard, Jeloková, Jana, Palkovits, Miklós

“…Responses of central noradrenergic (NE) neurons to stressors like immobilization (IMO), cold exposure, insulin-induced hypoglycemia, and cellular…”
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Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib by Deeken, John F., Beumer, Jan H., Anders, Nicole M., Wanjiku, Teresia, Rusnak, Milan, Rudek, Michelle A.

“…Purpose Prevalence of non-AIDS-defining cancers (NADCs) has increased in the era of potent antiretroviral treatments. Incidence rates of NADCs now exceed…”
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Alpha‐Synuclein induces hyperphosphorylation of Tau in the MPTP model of Parkinsonism by Duka, Tetyana, Rusnak, Milan, Drolet, Robert E., Duka, Valeriy, Wersinger, Christophe, Goudreau, John L., Sidhu, Anita

“…Many neurodegenerative diseases associated with functional Tau dysregulation, including Alzheimer's disease (AD) and other tauopathies, also show α‐synuclein…”
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Differential effects of forskolin on tyrosine hydroxylase gene transcription in identified brainstem catecholaminergic neuronal subtypes in organotypic culture by Rusnak, Milan, Gainer, Harold

“…The regulation of gene expression of tyrosine hydroxylase (TH), the rate‐limiting enzyme in catecholamine synthesis, was studied in brainstem noradrenergic…”
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Repeated immobilization stress reduces rat vertebral bone growth and osteocalcin by Patterson-Buckendahl, P, Rusnák, M, Fukuhara, K, Kvetnanský, R

“…We previously showed that psychological stressors alter plasma levels of osteocalcin (pOC), a bone-specific mineral binding protein, in ways that differ with…”
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Highly Potent and Specific GSK-3β Inhibitors That Block Tau Phosphorylation and Decrease α-Synuclein Protein Expression in a Cellular Model of Parkinson's Disease by Kozikowski, Alan P., Gaisina, Irina N., Petukhov, Pavel A., Sridhar, Jayalakshmi, King, LaShaunda T., Blond, Sylvie Y., Duka, Tetyana, Rusnak, Milan, Sidhu, Anita

“…Research by Klein and co‐workers suggests that the inhibition of GSK‐3β by small molecules may offer an important strategy in the treatment of a number of…”
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Maternal Absence of the Parathyroid Hormone 2 Receptor Affects Postnatal Pup Development by Coutellier, L., Logemann, A., Rusnak, M., Usdin, T. B.

“…During the lactation period, mothers have a variety of adaptive changes in brain physiology and behaviour that allow them to properly raise their pups. The…”
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Depolarization and Neurotransmitter Regulation of Vasopressin Gene Expression in the Rat Suprachiasmatic Nucleus In Vitro by Rusnak, Milan, E. Toth, Zsuzsanna, House, Shirley B, Gainer, Harold

“…Vasopressin (VP) transcription in the rat suprachiasmatic nucleus (SCN) in organotypic culture was studied by in situ hybridization histochemistry using an…”
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