Search Results - "Rusnak, F"

Calcineurin: Form and Function by Rusnak, Frank, Mertz, Pamela

“…Section of Hematology Research and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota; and Department of Chemistry and…”
Get full text

Carotid baroreceptors. Their role in ischemic cerebral stroke, coronary artery disease, and /INS;arterial hypertension. Are the changes in baroreceptor sensitivity age-related? by Bartko, D, Blazicek, P, Gombosova, Z, Danihel, L, Drobna, E, Kodaj, J, Fabčin, J, Kubala, J, Lacko, A, Hrubon, A, Rusnak, F, Labanczova, L, Kurca, E, Fillip, I, Valach, M

Get full text

Evidence for Isoniazid-Dependent Free Radical Generation Catalyzed by Mycobacterium tuberculosis KatG and the Isoniazid-Resistant Mutant KatG(S315T) by Wengenack, Nancy L, Rusnak, Frank

“…The antitubercular agent isoniazid can be activated by Mycobacterium tuberculosis KatG using either a peroxidase compound I/II or a superoxide-dependent…”
Get full text

Structure of the Bacteriophage λ Ser/Thr Protein Phosphatase with Sulfate Ion Bound in Two Coordination Modes by Voegtli, Walter C, White, Daniel J, Reiter, Nicholas J, Rusnak, Frank, Rosenzweig, Amy C

“…The protein phosphatase encoded by bacteriophage λ (λPP) belongs to a family of Ser/Thr phosphatases (Ser/Thr PPases) that includes the eukaryotic protein…”
Get full text

Immunosuppressants implicate protein phosphatase regulation of K+ channels in guard cells by Luan, S. (Harvard University, Cambridge, MA), Li, W, Rusnak, F, Assmann, S.M, Schreiber, S.L

“…The elevation of Ca2+ levels in the cytoplasm inactivates inward-rectifying K+ channels that play a central role in regulating the apertures of stomatal pores…”
Get full text

Direct Modulation of Calmodulin Targets by the Neuronal Calcium Sensor NCS-1 by Schaad, Nicolas C., De Castro, Edouard, Nef, Serge, Hegi, Sarah, Hinrichsen, Robert, Martone, Maryann E., Ellisman, Mark H., Sikkink, Robert, Rusnak, Frank, Sygush, Jurgen, Nef, Patrick

“…Ca2+ and its ubiquitous intracellular receptor calmodulin (CaM) are required in the nervous system, among a host of cellular responses, for the modulation of…”
Get full text

Cyclosporin-Mediated Inhibition of Bovine Calcineurin by Cyclophilins A and B by Selene K.-H. Swanson, Born, Timothy, Zydowsky, Lynne D., Cho, Hyeongjin, Chang, Howard Y., Walsh, Christopher T., Rusnak, Frank

“…The Ca2+-and calmodulin-dependent protein phosphatase calcineurin is inhibited by the immunosuppressant drug cyclosporin A in the presence of cyclophilin A or…”
Get full text

Metalloenzymes and signal transduction: the protein serine/threonine phosphatases, a novel class of binuclear metal-containing enzymes by Rusnak, F., Yu, Lian, Mertz, Pamela

Get full text

Thrombin induced inhibition of neurite outgrowth from dorsal root ganglion neurons by Gill, Jagjit S, Pitts, Kelly, Rusnak, Frank M, Owen, Whyte G, Windebank, Anthony J

“…Thrombin is a multifunctional protease. Recent studies on cultured neuronal cells have suggested a function for thrombin in the development and maintenance of…”
Get full text

Redox Potential Measurements of the Mycobacterium tuberculosis Heme Protein KatG and the Isoniazid-Resistant Enzyme KatG(S315T):  Insights into Isoniazid Activation by Wengenack, Nancy L, Lopes, Helder, Kennedy, Matthew J, Tavares, Pedro, Pereira, Alice S, Moura, Isabel, Moura, José J. G, Rusnak, Frank

“…Mycobacterium tuberculosis KatG is a multifunctional heme enzyme responsible for activation of the antibiotic isoniazid. A KatG(S315T) point mutation is found…”
Get full text

Redox regulation of calcineurin in T-lymphocytes by Reiter, T A, Abraham, R T, Choi, M, Rusnak, F

“…To explore whether the Ca(2+)/calmodulin-dependent protein phosphatase calcineurin is subject to redox regulation in vivo, we used a luciferase reporter gene…”
Get full text

Further characterization of the spin coupling observed in oxidized hydrogenase from Chromatium vinosum. A Mössbauer and multifrequency EPR study by SURERUS, K. K, MIN CHEN, VAN DER ZWAAN, J. W, RUSNAK, F. M, KOLK, M, DUIN, E. C, ALBRACHT, S. P. J, MÜNCK, E

“…Hydrogenase from Chromatium vinosum contains 1 Ni, 11-12 Fe, and ca. 9 sulfides. EPR and Mössbauer studies of the enzyme prepared in four different oxidation…”
Get full text

Spectroscopic Comparison of the Heme Active Sites in WT KatG and Its S315T Mutant by Lukat-Rodgers, Gudrun S, Wengenack, Nancy L, Rusnak, Frank, Rodgers, Kenton R

“…KatG, the catalase-peroxidase from Mycobacterium tuberculosis, has been characterized by resonance Raman, electron spin resonance, and visible spectroscopies…”
Get full text

Carbon Monoxide Adducts of KatG and KatG(S315T) as Probes of the Heme Site and Isoniazid Binding by Lukat-Rodgers, Gudrun S, Wengenack, Nancy L, Rusnak, Frank, Rodgers, Kenton R

“…KatG, the catalase peroxidase from Mycobacterium tuberculosis, is important in the activation of the antitubercular drug, isoniazid. About 50% of…”
Get full text

Properties of a Copper-Containing Cytochrome ba3: A Second Terminal Oxidase from the Extreme Thermophile Thermus thermophilus by Zimmermann, Barbara H., Nitsche, Carmen I., Fee, James A., Rusnak, Frank, Münck, Eckard

“…We describe an alternate terminal oxidase found in the plasma membrane of Thermus thermophilus and designate it cytochrome ba3. The enzyme consists of a single…”
Get full text

Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein by ARCHER, M., CARVALHO, A.L., TEIXEIRA, S., MOURA, I., MOURA, J.J.G., RUSNAK, F., ROMÃO, M.J.

“…Desulforedoxin (Dx), isolated from the sulfate reducing bacterium Desulfovibrio gigas, is a small homodimeric (2 × 36 amino acids) protein. Each subunit…”
Get full text

NMR solution structures of two mutants of desulforedoxin by Goodfellow, B.J., Rusnak, F., Moura, I., Ascenso, C.S, Moura, J.J.G.

“…The differences in geometry at the metal centres in the two known [Fe–4S] proteins rubredoxin (Rd) and desulforedoxin (Dx) are postulated to be a result of the…”
Get full text

Overexpression and characterization of a recombinant form of rat calcineurin A by Haddy, A, Rusnak, F

“…Overexpression of rat recombinant calcineurin A catalytic subunit in E. coli was achieved using a system under control of the T7 promoter. The specific…”
Get more information

Subcloning of the enterobactin biosynthetic gene entB: expression, purification, characterization and substrate specificity of isochorismatase by Rusnak, Frank, Liu, Jun, Quinn, Nina, Berchtold, Glenn A, Walsh, Christopher T

“…The Escherichia coli entB gene, coding for the enterobactin biosynthetic enzyme isochorismatase, has been subcloned into the multicopy plasmid pKK223-3 under…”
Get full text

NMR determination of the global structure of the 113Cd derivative of desulforedoxin: Investigation of the hydrogen bonding pattern at the metal center by Goodfellow, B.J., Moura, I., Moura, J.J.G., Rusnak, F., Domke, T.

“…Desulforedoxin (Dx) is a simple homodimeric protein isolated from Desulfovibrio gigas (Dg) containing a distorted rubredoxin‐like center with one iron…”
Get full text