Search Results - "Rusmini, P"
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Insights on Human Small Heat Shock Proteins and Their Alterations in Diseases
Published in Frontiers in molecular biosciences (25-02-2022)“…The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of chaperones (HSPB1-HSPB10), characterized by a low molecular weight and…”
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Synergic prodegradative activity of Bicalutamide and trehalose on the mutant androgen receptor responsible for spinal and bulbar muscular atrophy
Published in Human molecular genetics (01-01-2015)“…Spinal and bulbar muscular atrophy (SBMA) is an X-linked motoneuron disease due to a CAG triplet-repeat expansion in the androgen receptor (AR) gene, which is…”
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Androgen‐induced neurite outgrowth is mediated by neuritin in motor neurones
Published in Journal of neurochemistry (01-01-2005)“…In the brain, the spinal cord motor neurones express the highest levels of the androgen receptor (AR). Experimental data have suggested that neurite outgrowth…”
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Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration
Published in Autophagy (03-04-2019)“…Macroautophagy/autophagy, a defense mechanism against aberrant stresses, in neurons counteracts aggregate-prone misfolded protein toxicity. Autophagy induction…”
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241st ENMC international workshop: Towards a European unifying lab for Kennedy's disease. 15–17th February, 2019 Hoofddorp, The Netherlands
Published in Neuromuscular disorders : NMD (01-09-2019)Get full text
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The Androgen Derivative 5 alpha -Androstane-3 beta ,17 beta -Diol Inhibits Prostate Cancer Cell Migration Through Activation of the Estrogen Receptor beta Subtype
Published in Cancer research (Chicago, Ill.) (15-06-2005)“…Prostate cancer growth depends, in its earlier stages, on androgens and is usually pharmacologically modulated with androgen blockade. However,…”
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Dysregulation of axonal transport and motorneuron diseases
Published in Biology of the cell (01-02-2011)“…MNDs (motorneuron diseases) are neurodegenerative disorders in which motorneurons located in the motor cortex, in the brainstem and in the spinal cord are…”
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Tetracycline-regulated gene expression in the NSC-34-tTA cell line for investigation of motor neuron diseases
Published in Brain research. Molecular brain research. (31-10-2005)“…The motor neuron-like cell line NSC-34 has become a widely used in vitro model for motor neuron biology and pathology. We established a tetracycline-regulated…”
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