Search Results - "Rusinova, Elena"

BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice by Cheung, Kalung, Lu, Geming, Sharma, Rajal, Vincek, Adam, Zhang, Ruihua, Plotnikov, Alexander N., Zhang, Fan, Zhang, Qiang, Ju, Ying, Hu, Yuan, Zhao, Li, Han, Xinye, Meslamani, Jamel, Xu, Feihong, Jaganathan, Anbalagan, Shen, Tong, Zhu, Hongfa, Rusinova, Elena, Zeng, Lei, Zhou, Jiachi, Yang, Jianjun, Peng, Liang, Ohlmeyer, Michael, Walsh, Martin J., Zhang, David Y., Xiong, Huabao, Zhou, Ming-Ming

“…T-helper 17 (Th17) cells have important functions in adaptor immunity and have also been implicated in inflammatory disorders. The bromodomain and…”
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Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes by Di Micco, Raffaella, Fontanals-Cirera, Barbara, Low, Vivien, Ntziachristos, Panagiotis, Yuen, Stephanie K, Lovell, Claudia D, Dolgalev, Igor, Yonekubo, Yoshiya, Zhang, Guangtao, Rusinova, Elena, Gerona-Navarro, Guillermo, Cañamero, Marta, Ohlmeyer, Michael, Aifantis, Iannis, Zhou, Ming-Ming, Tsirigos, Aristotelis, Hernando, Eva

“…Transcription factors and chromatin-remodeling complexes are key determinants of embryonic stem cell (ESC) identity. Here, we demonstrate that BRD4, a member…”
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Gelation in Alginate-Based Magnetic Suspensions Favored by Poor Interaction among Sodium Alginate and Embedded Particles by Safronov, Alexander P, Rusinova, Elena V, Terziyan, Tatiana V, Zemova, Yulia S, Kurilova, Nadezhda M, Beketov, Igor. V, Zubarev, Andrey Yu

“…Alginate gels are extensively tested in biomedical applications for tissue regeneration and engineering. In this regard, the modification of alginate gels and…”
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Effect of a magnetic field on the rheological properties of iron oxide–water–glycerol system by Vshivkov, Sergey A., Rusinova, Elena V., Galyas, Andrei G.

“…The viscosity of magnetic fluids consisting of iron oxide nanoparticles, water, and glycerol has been studied under the conditions of a rotational flow in the…”
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Calcium Binding to Calmodulin Mutants Monitored by Domain-Specific Intrinsic Phenylalanine and Tyrosine Fluorescence by VanScyoc, Wendy S., Sorensen, Brenda R., Rusinova, Elena, Laws, William R., Ross, J.B. Alexander, Shea, Madeline A.

“…Cooperative calcium binding to the two homologous domains of calmodulin (CaM) induces conformational changes that regulate its association with and activation…”
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Debates on sound in the 1970s and 1980s and the beginning of vocational training for sound editors at VGIK by Rusinova, Elena

“…Part of a special issue devoted to the centenary of the Film Institute VGIK, this article consists of an introduction to and contextualisation of the…”
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Selective Chemical Modulation of Gene Transcription Favors Oligodendrocyte Lineage Progression by Gacias, Mar, Gerona-Navarro, Guillermo, Plotnikov, Alexander N., Zhang, Guangtao, Zeng, Lei, Kaur, Jasbir, Moy, Gregory, Rusinova, Elena, Rodriguez, Yoel, Matikainen, Bridget, Vincek, Adam, Joshua, Jennifer, Casaccia, Patrizia, Zhou, Ming-Ming

“…Lysine acetylation regulates gene expression through modulating protein-protein interactions in chromatin. Chemical inhibition of acetyl-lysine binding…”
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Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer by Shi, Jian, Wang, Yifan, Zeng, Lei, Wu, Yadi, Deng, Jiong, Zhang, Qiang, Lin, Yiwei, Li, Junlin, Kang, Tiebang, Tao, Min, Rusinova, Elena, Zhang, Guangtao, Wang, Chi, Zhu, Haining, Yao, Jun, Zeng, Yi-Xin, Evers, B. Mark, Zhou, Ming-Ming, Zhou, Binhua P.

“…Twist is a key transcription activator of epithelial-mesenchymal transition (EMT). It remains unclear how Twist induces gene expression. Here we report a…”
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Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain by Ablooglu, Ararat J., Frankel, Mark, Rusinova, Elena, Ross, John B. Alexander, Kohanski, Ronald A.

“…Low catalytic efficiency of protein kinases often results from intrasteric inhibition caused by the activation loop blocking the active site. In the insulin…”
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Down-regulation of NF-κB Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition by Zhang, Guangtao, Liu, Ruijie, Zhong, Yifei, Plotnikov, Alexander N., Zhang, Weijia, Zeng, Lei, Rusinova, Elena, Gerona-Nevarro, Guillermo, Moshkina, Natasha, Joshua, Jennifer, Chuang, Peter Y., Ohlmeyer, Michael, He, John Cijiang, Zhou, Ming-Ming

“…NF-κB-mediated inflammation is the major pathology in chronic kidney diseases, including HIV-associated nephropathy (HIVAN) that ultimately progresses to end…”
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Structure-Guided Design of Potent Diazobenzene Inhibitors for the BET Bromodomains by Zhang, Guangtao, Plotnikov, Alexander N, Rusinova, Elena, Shen, Tong, Morohashi, Keita, Joshua, Jennifer, Zeng, Lei, Mujtaba, Shiraz, Ohlmeyer, Michael, Zhou, Ming-Ming

“…BRD4, characterized by two acetyl-lysine binding bromodomains and an extra-terminal (ET) domain, is a key chromatin organizer that directs gene activation in…”
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Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor by Frankel, Mark, Ablooglu, Ararat J., Leone, Joseph W., Rusinova, Elena, Ross, J. B. Alexander, Heinrikson, Robert L., Kohanski, Ronald A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Coactivator CBP by Plotnikov, Alexander N., Yang, Shuai, Zhou, Thomas Jiachi, Rusinova, Elena, Frasca, Antonio, Zhou, Ming-Ming

“…Bromodomain functions as the acetyl-lysine binding domains to regulate gene transcription in chromatin. Bromodomains are rapidly emerging as new epigenetic…”
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Structural Insights into Acetylated-Histone H4 Recognition by the Bromodomain-PHD Finger Module of Human Transcriptional Co-Activator CBP by Plotnikov, Alexander N., Yang, Shuai, Zhou, Thomas Jiachi, Rusinova, Elena, Frasca, Antonio, Zhou, Ming-Ming

“…Bromodomain function as the acetyl-lysine binding domains to regulate gene transcription in chromatin. Bromodomains are rapidly emerging as new epigenetic drug…”
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Lipid-Bound Factor Xa Regulates Tissue Factor Activity by Hathcock, James, Rusinova, Elena, Vaananen, Heikki, Nemerson, Yale

“…The activation of coagulation factor X by tissue factor (TF) and coagulation factor VIIa (VIIa) on a phospholipid surface is thought to be the key step in the…”
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Factor Xa Control of the Extrinsic Pathway: A Different View of the Regulation of Coagulation by Hathcock, James J., Rusinova, Elena, Nemerson, Yale

“…The activation of factor X by Tissue Factor(TF):VIIa on a membrane surface is one of the principal events in the initiation of coagulation. We have previously…”
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Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition by Zhang, Guangtao, Liu, Ruijie, Zhong, Yifei, Plotnikov, Alexander N., Zhang, Weijia, Zeng, Lei, Rusinova, Elena, Gerona-Nevarro, Guillermo, Moshkina, Natasha, Joshua, Jennifer, Chuang, Peter Y., Ohlmeyer, Michael, He, John Cijiang, Zhou, Ming-Ming

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Disrupting the Interaction of BRD4 with Di-acetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer by Shi, Jian, Wang, Yifan, Zeng, Lei, Wu, Yadi, Deng, Jiong, Zhang, Qiang, Lin, Yiwei, Li, Junlin, Kang, Tiebang, Tao, Min, Rusinova, Elena, Zhang, Guangtao, Wang, Chi, Zhu, Haining, Yao, Jun, Zeng, Yi-Xin, Evers, B. Mark, Zhou, Ming-Ming, Zhou, Binhua P.

“…Twist is a key transcription activator of epithelial-mesenchymal transition (EMT). It remains unclear how Twist induces gene expression. Here we reported a…”
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Antiphospholipid antibodies accelerate plasma coagulation by inhibiting annexin-V binding to phospholipids : A lupus procoagulant phenomenon by RAND, J. H, WU, X.-X, ANDREE, H. A. M, ROSS, J. B. A, RUSINOVA, E, GASCON-LEMA, M. G, CALANDRI, C, HARPEL, P. C

“…The antiphospholipid syndrome is a thrombophilic condition marked by antibodies that recognize anionic phospholipid-protein cofactor complexes. We recently…”
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Antiphospholipid Antibodies Accelerate Plasma Coagulation by Inhibiting Annexin-V Binding to Phospholipids: A “Lupus Procoagulant” Phenomenon by Rand, Jacob H., Wu, Xiao-Xuan, Andree, Harry A.M., Ross, J.B. Alexander, Rusinova, Elena, Gascon-Lema, Mayra G., Calandri, Cesare, Harpel, Peter C.

“…The antiphospholipid syndrome is a thrombophilic condition marked by antibodies that recognize anionic phospholipid-protein cofactor complexes. We recently…”
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