Search Results - "Rusiecka, Olga M"
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Pannexin1 channels—a potential therapeutic target in inflammation
Published in Frontiers in cell and developmental biology (09-11-2022)“…An exaggerated inflammatory response is the hallmark of a plethora of disorders. ATP is a central signaling molecule that orchestrates the initiation and…”
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Cold Exposure Rejuvenates the Metabolic Phenotype of Panx1 -/- Mice
Published in Biomolecules (Basel, Switzerland) (01-09-2024)“…Pannexin1 (Panx1) ATP channels are important in adipocyte biology, potentially influencing energy storage and expenditure. We compared the metabolic phenotype…”
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Canonical and Non-Canonical Roles of Connexin43 in Cardioprotection
Published in Biomolecules (Basel, Switzerland) (23-08-2020)“…Since the mid-20th century, ischemic heart disease has been the world's leading cause of death. Developing effective clinical cardioprotection strategies would…”
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Mitochondrial pannexin1 controls cardiac sensitivity to ischaemia/reperfusion injury
Published in Cardiovascular research (24-10-2023)“…Abstract Aims No effective therapy is available in clinics to protect the heart from ischaemia/reperfusion (I/R) injury. Endothelial cells are activated after…”
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Structure-Based Design and Synthesis of Stapled 10Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases
Published in Journal of medicinal chemistry (28-09-2023)“…Following a rational design, a series of macrocyclic (“stapled”) peptidomimetics of 10Panx1, the most established peptide inhibitor of Pannexin1 (Panx1)…”
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Non-canonical roles of connexins
Published in Progress in biophysics and molecular biology (01-07-2020)“…Gap junctions mediate cellular communication and homeostasis by controlling the intercellular exchange of small and hydrophilic molecules and ions. Gap…”
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Structure-Based Design and Synthesis of Stapled 10 Panx1 Analogues for Use in Cardiovascular Inflammatory Diseases
Published in Journal of medicinal chemistry (28-09-2023)Get full text
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RB459 and RB462 antibodies recognize mouse Pannexin1 protein by immunofluorescent staining
Published in Antibody Reports (07-06-2019)“…The recombinant antibodies RB459 and RB462 recognize mouse Pannexin1 (Panx1) by immunofluorescent staining of a mouse cardiac endothelial cell line, a murine…”
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