Search Results - "Rushdi, Muaz"

Receptor-mediated cell mechanosensing by Chen, Yunfeng, Ju, Lining, Rushdi, Muaz, Ge, Chenghao, Zhu, Cheng

“…Mechanosensing describes the ability of a cell to sense mechanical cues of its microenvironment, including not only all components of force, stress, and strain…”
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A CRISPR/molecular beacon hybrid system for live-cell genomic imaging by Wu, Xiaotian, Mao, Shiqi, Yang, Yantao, Rushdi, Muaz N, Krueger, Christopher J, Chen, Antony K

“…Abstract The clustered regularly interspersed short palindromic repeat (CRISPR) gene-editing system has been repurposed for live-cell genomic imaging, but…”
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Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy by Yang, Yantao, Qu, Na, Tan, Jie, Rushdi, Muaz N., Krueger, Christopher J., Chen, Antony K.

“…During HIV-1 assembly, the retroviral structural protein Gag forms an immature capsid, containing thousands of Gag molecules, at the plasma membrane (PM)…”
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Mechanotransduction in T Cell Development, Differentiation and Function by Rushdi, Muaz, Li, Kaitao, Yuan, Zhou, Travaglino, Stefano, Grakoui, Arash, Zhu, Cheng

“…Cells in the body are actively engaging with their environments that include both biochemical and biophysical aspects. The process by which cells convert…”
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Inhibition of retroviral Gag assembly by non-silencing miRNAs promotes autophagic viral degradation by Qu, Na, Ma, Zhao, Zhang, Mengrao, Rushdi, Muaz N., Krueger, Christopher J., Chen, Antony K.

“…We recently reported an unconventional mechanism by which miRNAs inhibit HIV-1 viral production. This occurs when miRNAs bind nonspecifically to the viral…”
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Catch bond models may explain how force amplifies TCR signaling and antigen discrimination by Choi, Hyun-Kyu, Cong, Peiwen, Ge, Chenghao, Natarajan, Aswin, Liu, Baoyu, Zhang, Yong, Li, Kaitao, Rushdi, Muaz Nik, Chen, Wei, Lou, Jizhong, Krogsgaard, Michelle, Zhu, Cheng

“…The TCR integrates forces in its triggering process upon interaction with pMHC. Force elicits TCR catch-slip bonds with strong pMHCs but slip-only bonds with…”
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Cooperative binding of T cell receptor and CD4 to peptide-MHC enhances antigen sensitivity by Rushdi, Muaz Nik, Pan, Victor, Li, Kaitao, Choi, Hyun-Kyu, Travaglino, Stefano, Hong, Jinsung, Griffitts, Fletcher, Agnihotri, Pragati, Mariuzza, Roy A., Ke, Yonggang, Zhu, Cheng

“…Antigen recognition by the T cell receptor (TCR) of CD4 + T cells can be greatly enhanced by the coreceptor CD4. Yet, understanding of the molecular mechanism…”
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Programmable Multivalent DNA-Origami Tension Probes for Reporting Cellular Traction Forces by Dutta, Palash K., Zhang, Yun, Blanchard, Aaron T., Ge, Chenghao, Rushdi, Muaz, Weiss, Kristin, Zhu, Cheng, Ke, Yonggang, Salaita, Khalid

“…Mechanical forces are central to most, if not all, biological processes, including cell development, immune recognition, and metastasis. Because the cellular…”
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Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes by Ju, Lining, Chen, Yunfeng, Rushdi, Muaz Nik, Chen, Wei, Zhu, Cheng

“…Upon engagement with a specific ligand, a cell surface receptor transduces intracellular signals to activate various cellular functions. This chapter describes…”
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T cells exert force for pMHC pull-ups by Ge, Chenghao, Rushdi, Muaz Nik, Zhu, Cheng

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Endothelial and leukocyte heparan sulfates regulate the development of allergen-induced airway remodeling in a mouse model by Ge, Xiao Na, Ha, Sung Gil, Rao, Amrita, Greenberg, Yana G, Rushdi, Muaz Nik, Esko, Jeffrey D, Rao, Savita P, Sriramarao, P

“…Heparan sulfate (HS) proteoglycans (HSPGs) participate in several aspects of inflammation because of their ability to bind to growth factors, chemokines,…”
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