Search Results - "Rush, Natalia I."

Adipose Stem Cell Treatment in Mice Attenuates Lung and Systemic Injury Induced by Cigarette Smoking by SCHWEITZER, Kelly S, JOHNSTONE, Brian H, KAMOCKI, Krzysztof, BROWN, Mary Beth, PRESSON, Robert G, BROXMEYER, Hal E, MARCH, Keith L, PETRACHE, Irina, GARRISON, Jana, RUSH, Natalia I, COOPER, Scott, TRAKTUEV, Dmitry O, DONGNI FENG, ADAMOWICZ, Jeremy J, VAN DEMARK, Mary, FISHER, Amanda J

“…Adipose-derived stem cells express multiple growth factors that inhibit endothelial cell apoptosis, and demonstrate substantial pulmonary trapping after…”
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Active trafficking of alpha 1 antitrypsin across the lung endothelium by Lockett, Angelia D, Brown, Mary Beth, Santos-Falcon, Nieves, Rush, Natalia I, Oueini, Houssam, Oberle, Amber J, Bolanis, Esther, Fragoso, Miryam A, Petrusca, Daniela N, Serban, Karina A, Schweitzer, Kelly S, Presson, Jr, Robert G, Campos, Michael, Petrache, Irina

“…The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung…”
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Stimulation of Sphingosine 1-Phosphate Signaling as an Alveolar Cell Survival Strategy in Emphysema by Diab, Khalil J, Adamowicz, Jeremy J, Kamocki, Krzysztof, Rush, Natalia I, Garrison, Jana, Gu, Yuan, Schweitzer, Kelly S, Skobeleva, Anastasia, Rajashekhar, Gangaraju, Hubbard, Walter C, Berdyshev, Evgeny V, Petrache, Irina

“…Vascular endothelial growth factor receptor (VEGFR) inhibition increases ceramides in lung structural cells of the alveolus, initiating apoptosis and alveolar…”
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Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells by Lockett, Angelia D, Petrusca, Daniela N, Justice, Matthew J, Poirier, Christophe, Serban, Karina A, Rush, Natalia I, Kamocka, Malgorzata, Predescu, Dan, Predescu, Sanda, Petrache, Irina

“…In addition to exerting a potent anti-elastase function, α-1 antitrypsin (A1AT) maintains the structural integrity of the lung by inhibiting endothelial…”
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Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages by Petrusca, Daniela N., Gu, Yuan, Adamowicz, Jeremy J., Rush, Natalia I., Hubbard, Walter C., Smith, Patricia A., Berdyshev, Evgeni V., Birukov, Konstantin G., Lee, Chao-Hung, Tuder, Rubin M., Twigg, Homer L., Vandivier, R. William, Petrache, Irina

“…A decreased clearance of apoptotic cells (efferocytosis) by alveolar macrophages (AM) may contribute to inflammation in emphysema. The up-regulation of…”
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Mechanism of α‐1 antitrypsin endocytosis by lung endothelium by Sohrab, Sadaf, Petrusca, Daniela N., Lockett, Angelia D., Schweitzer, Kelly S., Rush, Natalia I., Gu, Yuan, Kamocki, Krzysztof, Garrison, Jana, Petrache, Irina

“…ABSTRACT The integrity of lung alveoli is maintained by proper circulating levels of α‐1 antitrypsin (A1AT). Next to cigarette smoking, A1AT deficiency is a…”
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Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice by Clauss, Matthias, Voswinckel, Robert, Rajashekhar, Gangaraju, Sigua, Ninotchka L, Fehrenbach, Heinz, Rush, Natalia I, Schweitzer, Kelly S, Yildirim, Ali Ö, Kamocki, Krzysztof, Fisher, Amanda J, Gu, Yuan, Safadi, Bilal, Nikam, Sandeep, Hubbard, Walter C, Tuder, Rubin M, Twigg, 3rd, Homer L, Presson, Robert G, Sethi, Sanjay, Petrache, Irina

“…Pulmonary emphysema is a disease characterized by alveolar cellular loss and inflammation. Recently, excessive apoptosis of structural alveolar cells has…”
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RTP801 is required for ceramide-induced cell-specific death in the murine lung by Kamocki, Krzysztof, Van Demark, Mary, Fisher, Amanda, Rush, Natalia I, Presson, Jr, Robert G, Hubbard, Walter, Berdyshev, Evgeny V, Adamsky, Swetlana, Feinstein, Elena, Gandjeva, Aneta, Tuder, Rubin M, Petrache, Irina

“…Key host responses to the stress induced by environmental exposure to cigarette smoke (CS) are responsible for initiating pathogenic effects that may culminate…”
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Loss of cystic fibrosis transmembrane conductance regulator impairs lung endothelial cell barrier function and increases susceptibility to microvascular damage from cigarette smoke by Brown, Mary Beth, Hunt, William R., Noe, Julie E., Rush, Natalia I., Schweitzer, Kelly S., Leece, Thomas C., Moldobaeva, Aigul, Wagner, Elizabeth M., Dudek, Steven M., Poirier, Christophe, Presson, Robert G., Gulbins, Erich, Petrache, Irina

“…Abnormal lung microvascular endothelial vascular barrier function may contribute to pulmonary inflammation, such as that occurring during inhalation of…”
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Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke–induced emphysema in mice by Clauss, Matthias, Voswinckel, Robert, Rajashekhar, Gangaraju, Sigua, Ninotchka L., Fehrenbach, Heinz, Rush, Natalia I., Schweitzer, Kelly S., Yildirim, Ali Ö., Kamocki, Krzysztof, Fisher, Amanda J., Gu, Yuan, Safadi, Bilal, Nikam, Sandeep, Hubbard, Walter C., Tuder, Rubin M., Twigg, Homer L., Presson, Robert G., Sethi, Sanjay, Petrache, Irina

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Ceramide impairs apoptotic cells phagocytosis (efferocytosis) by alveolar macrophages by Petrusca, Daniela Nicoleta, Fisher, Amanda, Rush, Natalia I., Hubbard, Walter C., Smith, Patricia, Presson, Robert G., Petrache, Irina

“…Abstract only Pulmonary emphysema is characterized by a loss of alveolar cells via apoptosis along with an inflammatory response, which may be explained by…”
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Protective effects of adipose stem cells against cigarette‐smoke induced lung injury by Schweitzer, Kelly, Johnstone, Brian H., Traktuev, Dmitry, Garrison, Jana, Rush, Natalia I, Adamowicz, Jeremy J, Cook, Todd G, Feng, Dongni, March, Keith L., Petrache, Irina

“…Abstract only Adipose‐derived stem cells (ASCs) express several critical determinants of lung rejuvenation, thus providing components necessary for tissues to…”
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