Search Results - "Rush, Matthew J. P."

High-Resolution Filtering for Improved Small Molecule Identification via GC/MS by Kwiecien, Nicholas W, Bailey, Derek J, Rush, Matthew J. P, Cole, Jason S, Ulbrich, Arne, Hebert, Alexander S, Westphall, Michael S, Coon, Joshua J

“…Gas chromatography/mass spectrometry (GC/MS) has long been considered one of the premiere analytical tools for small molecule analysis. Recently, a number of…”
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Top-Down Characterization of Proteins with Intact Disulfide Bonds Using Activated-Ion Electron Transfer Dissociation by Rush, Matthew J. P, Riley, Nicholas M, Westphall, Michael S, Coon, Joshua J

“…Here we report the fragmentation of disulfide linked intact proteins using activated-ion electron transfer dissociation (AI-ETD) for top-down protein…”
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Over 10000 Peptide Identifications from the HeLa Proteome by Using Single-Shot Capillary Zone Electrophoresis Combined with Tandem Mass Spectrometry by Sun, Liangliang, Hebert, Alexander S, Yan, Xiaojing, Zhao, Yimeng, Westphall, Michael S, Rush, Matthew J P, Zhu, Guijie, Champion, Matthew M, Coon, Joshua J, Dovichi, Norman J

“…Capillary zone electrophoresis (CZE)-tandem mass spectrometry (MS/MS) has recently attracted attention as a tool for shotgun proteomics. However, its…”
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Coupling Capillary Zone Electrophoresis with Electron Transfer Dissociation and Activated Ion Electron Transfer Dissociation for Top-Down Proteomics by Zhao, Yimeng, Riley, Nicholas M, Sun, Liangliang, Hebert, Alexander S, Yan, Xiaojing, Westphall, Michael S, Rush, Matthew J. P, Zhu, Guijie, Champion, Matthew M, Medie, Felix Mba, Champion, Patricia A. DiGiuseppe, Coon, Joshua J, Dovichi, Norman J

“…Top-down proteomics offers the potential for full protein characterization, but many challenges remain for this approach, including efficient protein…”
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A Calibration Routine for Efficient ETD in Large-Scale Proteomics by Rose, Christopher M., Rush, Matthew J. P., Riley, Nicholas M., Merrill, Anna E., Kwiecien, Nicholas W., Holden, Dustin D., Mullen, Christopher, Westphall, Michael S., Coon, Joshua J.

“…Electron transfer dissociation (ETD) has been broadly adopted and is now available on a variety of commercial mass spectrometers. Unlike collisional activation…”
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The Negative Mode Proteome with Activated Ion Negative Electron Transfer Dissociation (AI-NETD) by Riley, Nicholas M., Matthew J.P., Rush, Rose, Christopher M., Richards, Alicia L., Kwiecien, Nicholas W., Bailey, Derek J., Hebert, Alexander S., Westphall, Michael S., Coon, Joshua J.

“…The field of proteomics almost uniformly relies on peptide cation analysis, leading to an underrepresentation of acidic portions of proteomes, including…”
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Defining mitochondrial protein functions through deep multiomic profiling by Rensvold, Jarred W., Shishkova, Evgenia, Sverchkov, Yuriy, Miller, Ian J., Cetinkaya, Arda, Pyle, Angela, Manicki, Mateusz, Brademan, Dain R., Alanay, Yasemin, Raiman, Julian, Jochem, Adam, Hutchins, Paul D., Peters, Sean R., Linke, Vanessa, Overmyer, Katherine A., Salome, Austin Z., Hebert, Alexander S., Vincent, Catherine E., Kwiecien, Nicholas W., Rush, Matthew J. P., Westphall, Michael S., Craven, Mark, Akarsu, Nurten A., Taylor, Robert W., Coon, Joshua J., Pagliarini, David J.

“…Mitochondria are epicentres of eukaryotic metabolism and bioenergetics. Pioneering efforts in recent decades have established the core protein componentry of…”
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Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling by Stefely, Jonathan A, Kwiecien, Nicholas W, Freiberger, Elyse C, Richards, Alicia L, Jochem, Adam, Rush, Matthew J P, Ulbrich, Arne, Robinson, Kyle P, Hutchins, Paul D, Veling, Mike T, Guo, Xiao, Kemmerer, Zachary A, Connors, Kyle J, Trujillo, Edna A, Sokol, Jacob, Marx, Harald, Westphall, Michael S, Hebert, Alexander S, Pagliarini, David J, Coon, Joshua J

“…Proteomics, lipidomics and metabolomics of single gene deletion yeast strains sheds light on mitochondrial protein biology. Mitochondrial dysfunction is…”
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Multi-omic Mitoprotease Profiling Defines a Role for Oct1p in Coenzyme Q Production by Veling, Mike T., Reidenbach, Andrew G., Freiberger, Elyse C., Kwiecien, Nicholas W., Hutchins, Paul D., Drahnak, Michael J., Jochem, Adam, Ulbrich, Arne, Rush, Matthew J.P., Russell, Jason D., Coon, Joshua J., Pagliarini, David J.

“…Mitoproteases are becoming recognized as key regulators of diverse mitochondrial functions, although their direct substrates are often difficult to discern…”
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Caloric Restriction Engages Hepatic RNA Processing Mechanisms in Rhesus Monkeys by Rhoads, Timothy W., Burhans, Maggie S., Chen, Vincent B., Hutchins, Paul D., Rush, Matthew J.P., Clark, Josef P., Stark, Jaime L., McIlwain, Sean J., Eghbalnia, Hamid R., Pavelec, Derek M., Ong, Irene M., Denu, John M., Markley, John L., Coon, Joshua J., Colman, Ricki J., Anderson, Rozalyn M.

“…Caloric restriction (CR) extends lifespan and delays the onset of age-related disorders in diverse species. Metabolic regulatory pathways have been implicated…”
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Sulfur Pentafluoride is a Preferred Reagent Cation for Negative Electron Transfer Dissociation by Rush, Matthew J. P., Riley, Nicholas M., Westphall, Michael S., Syka, John E. P., Coon, Joshua J.

“…Negative mode proteome analysis offers access to unique portions of the proteome and several acidic post-translational modifications; however, traditional…”
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Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity by Stefely, Jonathan A., Licitra, Floriana, Laredj, Leila, Reidenbach, Andrew G., Kemmerer, Zachary A., Grangeray, Anais, Jaeg-Ehret, Tiphaine, Minogue, Catherine E., Ulbrich, Arne, Hutchins, Paul D., Wilkerson, Emily M., Ruan, Zheng, Aydin, Deniz, Hebert, Alexander S., Guo, Xiao, Freiberger, Elyse C., Reutenauer, Laurence, Jochem, Adam, Chergova, Maya, Johnson, Isabel E., Lohman, Danielle C., Rush, Matthew J.P., Kwiecien, Nicholas W., Singh, Pankaj K., Schlagowski, Anna I., Floyd, Brendan J., Forsman, Ulrika, Sindelar, Pavel J., Westphall, Michael S., Pierrel, Fabien, Zoll, Joffrey, Dal Peraro, Matteo, Kannan, Natarajan, Bingman, Craig A., Coon, Joshua J., Isope, Philippe, Puccio, Hélène, Pagliarini, David J.

“…The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of microbial PKLs and five human homologs, yet its biochemical activities…”
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Over 10 000 Peptide Identifications from the HeLa Proteome by Using Single-Shot Capillary Zone Electrophoresis Combined with Tandem Mass Spectrometry by Sun, Liangliang, Hebert, Alexander S., Yan, Xiaojing, Zhao, Yimeng, Westphall, Michael S., Rush, Matthew J. P., Zhu, Guijie, Champion, Matthew M., Coon, Joshua J., Dovichi, Norman J.

“…Capillary zone electrophoresis (CZE)–tandem mass spectrometry (MS/MS) has recently attracted attention as a tool for shotgun proteomics. However, its…”
Get full text

Over 10000 Peptide Identifications from the HeLa Proteome by Using Single-Shot Capillary Zone Electrophoresis Combined with Tandem Mass Spectrometry by Sun, Liangliang, Hebert, Alexander S, Yan, Xiaojing, Zhao, Yimeng, Westphall, Michael S, Rush, Matthew J P, Zhu, Guijie, Champion, Matthew M, Coon, Joshua J, Dovichi, Norman J

“…Capillary zone electrophoresis (CZE)-tandem mass spectrometry (MS/MS) has recently attracted attention as a tool for shotgun proteomics. However, its…”
Get full text

Over 10 000 peptide identifications from the HeLa proteome using single-shot capillary zone electrophoresis-tandem mass spectrometry by Sun, Liangliang, Hebert, Alexander S., Yan, Xiaojing, Zhao, Yimeng, Westphall, Michael S., Rush, Matthew J. P., Zhu, Guijie, Champion, Matthew M., Coon, Joshua J., Dovichi, Norman J.

“…Capillary zone electrophoresis-tandem mass spectrometry (CZE-MS/MS) has recently attracted attention as a tool for shotgun proteomics. However, its performance…”
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The Development and Implementation of Mass Spectrometry Methods for the Characterization of Proteins and Metabolites by Rush, Matthew J. P

“…The work described in this dissertation involves the development and application of mass spectrometry methods for the analysis of peptides, proteins, and…”
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Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity by Stefely, Jonathan A., Licitra, Floriana, Laredj, Leila, Reidenbach, Andrew G., Kemmerer, Zachary A., Grangeray, Anais, Jaeg-Ehret, Tiphaine, Minogue, Catherine E., Ulbrich, Arne, Hutchins, Paul D., Wilkerson, Emily M., Ruan, Zheng, Aydin, Deniz, Hebert, Alexander S., Guo, Xiao, Freiberger, Elyse C., Reutenauer, Laurence, Jochem, Adam, Chergova, Maya, Johnson, Isabel E., Lohman, Danielle C., Rush, Matthew J. P., Kwiecien, Nicholas W., Singh, Pankaj K., Schlagowski, Anna I., Floyd, Brendan J., Forsman, Ulrika, Sindelar, Pavel J., Westphall, Michael S., Pierrel, Fabien, Zoll, Joffrey, Dal Peraro, Matteo, Kannan, Natarajan, Bingman, Craig A., Coon, Joshua J., Isope, Philippe, Puccio, Hélène, Pagliarini, David J.

“…The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of microbial PKLs and five human homologs, yet its biochemical activities…”
Get full text

Over 10 000 Peptide Identifications from the HeLa Proteome by Using Single-Shot Capillary Zone Electrophoresis Combined with Tandem Mass Spectrometry by Sun, Liangliang, Hebert, Alexander S., Yan, Xiaojing, Zhao, Yimeng, Westphall, Michael S., Rush, Matthew J. P., Zhu, Guijie, Champion, Matthew M., Coon, Joshua J., Dovichi, Norman J.

“…Capillary zone electrophoresis (CZE)–tandem mass spectrometry (MS/MS) has recently attracted attention as a tool for shotgun proteomics. However, its…”
Get full text