Search Results - "Rush, Laura J"

MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1 by Garzon, Ramiro, Liu, Shujun, Fabbri, Muller, Liu, Zhongfa, Heaphy, Catherine E.A., Callegari, Elisa, Schwind, Sebastian, Pang, Jiuxia, Yu, Jianhua, Muthusamy, Natarajan, Havelange, Violaine, Volinia, Stefano, Blum, William, Rush, Laura J., Perrotti, Danilo, Andreeff, Michael, Bloomfield, Clara D., Byrd, John C., Chan, Kenneth, Wu, Lai-Chu, Croce, Carlo M., Marcucci, Guido

“…Aberrant DNA hypermethylation contributes to myeloid leukemogenesis by silencing structurally normal genes involved in hematopoiesis. MicroRNAs (miRNAs) are…”
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Aberrant Overexpression of IL-15 Initiates Large Granular Lymphocyte Leukemia through Chromosomal Instability and DNA Hypermethylation by Mishra, Anjali, Liu, Shujun, Sams, Gregory H., Curphey, Douglas P., Santhanam, Ramasamy, Rush, Laura J., Schaefer, Deanna, Falkenberg, Lauren G., Sullivan, Laura, Jaroncyk, Laura, Yang, Xiaojuan, Fisk, Harold, Wu, Lai-Chu, Hickey, Christopher, Chandler, Jason C., Wu, Yue-Zhong, Heerema, Nyla A., Chan, Kenneth K., Perrotti, Danilo, Zhang, Jianying, Porcu, Pierluigi, Racke, Frederick K., Garzon, Ramiro, Lee, Robert J., Marcucci, Guido, Caligiuri, Michael A.

“…How inflammation causes cancer is unclear. Interleukin-15 (IL-15) is a pro-inflammatory cytokine elevated in human large granular lymphocyte (LGL) leukemia…”
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A qualitative study of providers' perspectives on cross-institutional care coordination for pancreatic cancer: challenges and opportunities by DePuccio, Matthew J, Shiu-Yee, Karen, Kurien, Natasha A, Sarna, Angela, Waterman, Brittany L, Rush, Laura J, McAlearney, Ann Scheck, Ejaz, Aslam

“…Despite calls for regionalizing pancreatic cancer (PC) care to high-volume centers (HVCs), many patients with PC elect to receive therapy closer to their home…”
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COVID-19 vaccination perspectives among patients with Long COVID: A qualitative study by MacEwan, Sarah R, Rahurkar, Saurabh, Tarver, Willi L, Gaughan, Alice A, Rush, Laura J, Schamess, Andrew, McAlearney, Ann Scheck

“…Individuals who have Long COVID may have unique perspectives about COVID-19 vaccination due to the significant impact that COVID-19 has had on their lives…”
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Identifying beliefs driving COVID-19 vaccination: Lessons for effective messaging by MacEwan, Sarah R., Kenah, Eben, Dixon, Graham N., Stevens, Jack, Eiterman, Leanna Perez, Powell, Jonathan R., Gage, Christopher B., Rush, Laura J., Panchal, Ashish R., McAlearney, Ann Scheck

“…Increasing vaccination acceptance has been essential during the COVID-19 pandemic and in preparation for future public health emergencies. This study aimed to…”
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When Infections Are Found: A Qualitative Study Characterizing Best Management Practices for Central Line-Associated Bloodstream Infection and Catheter-Associated Urinary Tract Infection Performance Monitoring and Feedback by Gaughan, Alice A, MacEwan, Sarah R, Gregory, Megan E, Eramo, Jennifer L, Rush, Laura J, Hebert, Courtney L, McAlearney, Ann Scheck

“…Healthcare-associated infections (HAIs) remain a significant patient safety problem that can lead to illness and death, despite the implementation of clinical…”
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Understanding Concerns about COVID-19 and Vaccination: Perspectives from Kidney Transplant Recipients by MacEwan, Sarah R, Gaughan, Alice A, Dixon, Graham N, Olvera, Ramona G, Tarver, Willi L, Rahurkar, Saurabh, Rush, Laura J, Schenk, Austin D, Stevens, Jack, McAlearney, Ann Scheck

“…The COVID-19 pandemic poses a significant risk for immunosuppressed groups such as transplant patients. The purpose of this study was to improve our…”
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Perspectives of patients undergoing neoadjuvant chemotherapy for breast cancer during the COVID ‐19 pandemic by Gaughan, Alice A., MacEwan, Sarah R., Rush, Laura J., Gatti‐Mays, Margaret E., Pariser, Ashley C., McAlearney, Ann Scheck

“…Abstract Background The COVID‐19 pandemic resulted in a lapse in routine health care and cancer screenings for many individuals. This study sought to improve…”
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Perspectives of Volunteer Firefighters during the COVID-19 Pandemic: Stumbling Blocks and Silver Linings by Gaughan, Alice A, Rush, Laura J, MacEwan, Sarah R, Panchal, Ashish R, McAlearney, Ann Scheck

“…The COVID-19 pandemic has profoundly affected the lives of almost every individual in every nation, with numbers of infections continuing to grow. Across these…”
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An Opportunity to Understand Concerns about COVID-19 Vaccination: Perspectives from EMS Professionals by MacEwan, Sarah R, Gaughan, Alice A, Gregory, Megan E, Rush, Laura J, Powell, Jonathan R, Kurth, Jordan D, Panchal, Ashish R, McAlearney, Ann Scheck

“…Some healthcare professionals, including emergency medical service (EMS) professionals, remain hesitant about receiving COVID-19 vaccines. This study sought to…”
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The MLL partial tandem duplication: evidence for recessive gain-of-function in acute myeloid leukemia identifies a novel patient subgroup for molecular-targeted therapy by Whitman, Susan P., Liu, Shujun, Vukosavljevic, Tamara, Rush, Laura J., Yu, Li, Liu, Chunhui, Klisovic, Marko I., Maharry, Kati, Guimond, Martin, Strout, Matthew P., Becknell, Brian, Dorrance, Adrienne, Klisovic, Rebecca B., Plass, Christoph, Bloomfield, Clara D., Marcucci, Guido, Caligiuri, Michael A.

“…MLL (ALL-1) chimeric fusions and MLL partial tandem duplications (PTD) may have mechanistically distinct contributions to leukemogenesis. Acute myeloid…”
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Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets by RUSH, Laura J, RAVAL, Aparna, LIYANARACHCHI, Sandya, DAVULURI, Ramana, BYRD, John C, PLASS, Christoph, FUNCHAIN, Pauline, JOHNSON, Amy J, SMITH, Lisa, LUCAS, David M, BEMBEA, Melania, LIU, Te-Hui, HEEREMA, Nyla A, RASSENTI, Laura

“…CpG island methylation is an epigenetic alteration that contributes to tumorigenesis by transcriptional inactivation of genes. Little is known about the…”
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Aberrant DNA methylation of OLIG1, a novel prognostic factor in non-small cell lung cancer by Brena, Romulo M, Morrison, Carl, Liyanarachchi, Sandya, Jarjoura, David, Davuluri, Ramana V, Otterson, Gregory A, Reisman, David, Glaros, Selina, Rush, Laura J, Plass, Christoph

“…Lung cancer is the leading cause of cancer-related death worldwide. Currently, tumor, node, metastasis (TNM) staging provides the most accurate prognostic…”
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Restriction landmark genomic scanning for DNA methylation in cancer: past, present, and future applications by Rush, Laura J, Plass, Christoph

“…The field of molecular biology was revolutionized by the advent of gel electrophoresis. Restriction landmark genomic scanning (RLGS) is a type of…”
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BAALC, The Human Member of a Novel Mammalian Neuroectoderm Gene Lineage, is Implicated in Hematopoiesis and Acute Leukemia by Tanner, Stephan M., Austin, Jamie L., Leone, Gustavo, Rush, Laura J., Plass, Christoph, Heinonen, Kristiina, Mrózek, Krzysztof, Sill, Heinz, Knuutila, Sakari, Kolitz, Jonathan E., Archer, Kellie J., Caligiuri, Michael A., Bloomfield, Clara D., de la Chapelle, Albert

“…The molecular basis of human leukemia is heterogeneous. Cytogenetic findings are increasingly associated with molecular abnormalities, some of which are being…”
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Patient Experiences Navigating Care Coordination For Long COVID: A Qualitative Study by MacEwan, Sarah R., Rahurkar, Saurabh, Tarver, Willi L., Forward, Cortney, Eramo, Jennifer L., Teuschler, Lauren, Gaughan, Alice A., Rush, Laura J., Stanwick, Stacy, McConnell, Erin, Schamess, Andrew, McAlearney, Ann Scheck

“…Background Little is known about how to best evaluate, diagnose, and treat long COVID, which presents challenges for patients as they seek care. Objective…”
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Reporting time toxicity in prospective cancer clinical trials: A scoping review by Quinn, Patrick L., Saiyed, Shah, Hannon, Connor, Sarna, Angela, Waterman, Brittany L., Cloyd, Jordan M., Spriggs, Rodney, Rush, Laura J., McAlearney, Ann Scheck, Ejaz, Aslam

“…Purpose This review aimed to assess the measurement and reporting of time toxicity (i.e., time spent receiving care) within prospective oncologic studies…”
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The Impact of Long COVID on Employment and Well-Being: A Qualitative Study of Patient Perspectives by MacEwan, Sarah R, Rahurkar, Saurabh, Tarver, Willi L, Eiterman, Leanna Perez, Melnyk, Halia, Olvera, Ramona G, Eramo, Jennifer L, Teuschler, Lauren, Gaughan, Alice A, Rush, Laura J, Stanwick, Stacy, Burpee, Susan Bowman, McConnell, Erin, Schamess, Andrew, McAlearney, Ann Scheck

“…Exploring the experiences of Long COVID patients who face challenges with employment may inform improvements in how healthcare systems can provide holistic…”
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Utilization of Palliative and Hospice Care Among Pancreatic Cancer Patients at an Academic Center by Chawla, Mehak, Villarreal, Michael E., Waterman, Brittany L., Di Tosto, Gennaro, Gonzalez, Roberto, Sarna, Angela, Patel, Romal, Cloyd, Jordan, Pawlik, Timothy M., Rush, Laura J., McAlearney, Ann, Ejaz, Aslam

“…Pancreatic ductal adenocarcinoma has the lowest 5-y relative survival of all solid tumor malignancies. Palliative care can improve the quality of life of both…”
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Creating a Palliative Care Clinic for Patients with Cancer Pain and Substance Use Disorder by Kale, Sachin S., Tosto, Gennaro Di, Rush, Laura J., Kullgren, Justin, Russell, Deborah, Fried, Martin, Igboeli, Blessing, Teater, Julie, Jones, Katie Fitzgerald, Check, Devon K., Merlin, Jessica, McAlearney, Ann Scheck

“…Opioids are a first-line treatment for severe cancer pain. However, clinicians may be reluctant to prescribe opioids for patients with concurrent substance use…”
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