Search Results - "Rush, Elizabeth A"

Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors by Sander, Cindy A, Rush, Elizabeth A, Shi, Jian, Arantes, Lidia M R B, Tesi, Raymond J, Ross, Mark A, Calderon, Michael J, Watkins, Simon C, Kirkwood, John M, Ferris, Robert L, Butterfield, Lisa H, Vujanovic, Lazar

“…The effectiveness of MAPK pathway inhibitors (MAPKi) used to treat patients with BRAF-mutant melanoma is limited by a range of resistance mechanisms, including…”
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NPM-RAR, not the RAR-NPM reciprocal t(5;17)(q35;q21) acute promyelocytic leukemia fusion protein, inhibits myeloid differentiation by Pollock, Sheri L., Rush, Elizabeth A., Redner, Robert L.

“…Abstract The t(5;17) variant of acute promyelocytic leukemia (APL) fuses the nucleophosmin (NPM) gene at 5q35 with the retinoic acid receptor alpha (RARA) at…”
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The leukemic oncoprotein NPM1-RARA inhibits TP53 activity by Swaney, Erin M., Chattopadhyay, Anuja, Abecassis, Irina, Rush, Elizabeth A., Redner, Robert L.

“…The variant acute promyelocytic leukemia (APL) translocation t(5;17)(q35;q21) fuses the N-terminus of nucleophosmin (NPM1) to the retinoic acid receptor alpha…”
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Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade by Rush, Elizabeth A, Pollock, Sheri L, Abecassis, Irina, Redner, Robert L

“…Abstract The t(5;17)(q35;q21) APL variant results in expression of a fusion protein linking the N-terminus of nucleophosmin (NPM) to the C-terminus of the…”
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The NPM-RAR fusion protein associated with the t(5;17) variant of APL does not interact with PML by Rush, Elizabeth A., Schlesinger, Kimberly W., Watkins, Simon C., Redner, Robert L.

“…The PML protein localizes to regions of the nucleus known as nuclear bodies or PODs. However, in t(15;17) Acute Promyelocytic Leukemia (APL) blasts, PML is…”
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NPM-RAR Enhances NFκB Transcriptional Activity by Redner, Robert L., Abecassis, Irina, Rush, Elizabeth A., Chattopadhyay, Anuja

“…Abstract 5117 Acute Promyelocytic Leukemia (APL) is characterized by recurrent translocations of 17q21, which result in expression of fusion proteins of the…”
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Depression in family practice patients by Wright, J H, Bell, R A, Kuhn, C C, Rush, E A, Patel, N, Redmon, Jr, J E

“…Multiple factors have been described as significant contributors to depression in medical patients. This study attempts to assess the relative significance and…”
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Dominant-Negative Effect of NPM-RAR on NPM Mediated Regulation of p53 by Redner, Robert L., Swaney, Erin M., Rush, Elizabeth A.

“…We have been studying the variant Acute Promyelocytic Leukemia (APL) translocations with a view towards identifying common molecular pathways underlying APL…”
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The t(5;17) Variant of Acute Promyelocytic Leukemia Expresses a Nucleophosmin-Retinoic Acid Receptor Fusion by Redner, Robert L., Rush, Elizabeth A., Faas, Susan, Rudert, William A., Corey, Seth J.

“…We have studied an acute promyelocytic leukemia (APL) patient with a variant t(5; 17)(q32;q12). This translocation fuses the gene for the nucleolar…”
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The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties by Redner, Robert L., Chen, J. Don, Rush, Elizabeth A., Li, Hui, Pollock, Sheri L.

“…The t(5;17) variant of acute promyelocytic leukemia (APL) fuses the genes for nucleophosmin (NPM) and the retinoic acid receptor alpha (RARα). Two NPM-RAR…”
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The t(5;17) acute promyelocytic leukemia fusion protein NPM-RAR interacts with co-repressor and co-activator proteins and exhibits both positive and negative transcriptional properties by Redner, Robert L., Chen, J. Don, Rush, Elizabeth A., Li, Hui, Pollock, Sheri L.

“…The t(5;17) variant of acute promyelocytic leukemia (APL) fuses the genes for nucleophosmin (NPM) and the retinoic acid receptor alpha (RAR). Two NPM-RAR…”
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Reduction of NMDA receptors with dithiothreitol increases [ 3 H]‐MK‐801 binding and NMDA‐induced Ca 2+ fluxes by Reynolds, Ian J., Rush, Elizabeth A., Aizenman, Elias

“…We have investigated the modulation of N‐methyl‐ d ‐aspartate (NMDA) receptor activation by the sulphydryl redox reagents dithiothreitol (DTT) and…”
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Role of lipid solubility in the interaction of drugs with the N-methyl-D-aspartate receptor by Reynolds, I J, Rush, E A

“…We have examined the hypothesis that phenothiazines and tricyclic antidepressants interact with the N-methyl-D-aspartate (NMDA) receptor by mimicking the…”
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Reduction of NMDA receptors with dithiothreitol increases [3H]‐MK‐801 binding and NMDA‐induced Ca2+ fluxes by Reynolds, Ian J., Rush, Elizabeth A., Aizenman, Elias

“…1 We have investigated the modulation of N‐methyl‐d‐aspartate (NMDA) receptor activation by the sulphydryl redox reagents dithiothreitol (DTT) and…”
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