Search Results - "Rush, Catherine"

Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections by Hodgson, Kelly, Morris, Jodie, Bridson, Tahnee, Govan, Brenda, Rush, Catherine, Ketheesan, Natkunam

“…Summary Diabetes has been recognized as an important risk factor for a variety of intracellular bacterial infections, but research into the dysregulated immune…”
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Wnt Signaling Pathway Inhibitor Sclerostin Inhibits Angiotensin II–Induced Aortic Aneurysm and Atherosclerosis by Krishna, Smriti Murali, Seto, Sai-Wang, Jose, Roby J, Li, Jiaze, Morton, Susan K, Biros, Erik, Wang, Yutang, Nsengiyumva, Vianne, Lindeman, Jan H.N, Loots, Gabriela G, Rush, Catherine M, Craig, Jeffrey M, Golledge, Jonathan

“…OBJECTIVE—Sclerostin (SOST) has been identified as an important regulator of bone formation; however, it has not been previously implicated in arterial…”
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Identification of defective early immune responses to Burkholderia pseudomallei infection in a diet-induced murine model of type 2 diabetes by Morris, Jodie L., Govan, Brenda L., Rush, Catherine M., Ketheesan, Natkunam

“…Co-occurrence of bacterial infections with type 2 diabetes (T2D) is a global problem. Melioidosis caused by Burkholderia pseudomallei is 10 times more likely…”
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Anti‐streptococcal antibody and T‐cell interactions with vascular endothelial cells initiate the development of rheumatic carditis by Sikder, Suchandan, Rush, Catherine M., Govan, Brenda L., Alim, Md A., Ketheesan, Natkunam

“…The role of group A streptococcal and Streptococcus dysgalactiae subspecies equisimilis M‐protein specific Abs and T‐cells in endothelial cell activation was…”
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Disparate Effects of Metformin on Mycobacterium tuberculosis Infection in Diabetic and Nondiabetic Mice by Sathkumara, Harindra D, Hansen, Karyna, Miranda-Hernandez, Socorro, Govan, Brenda, Rush, Catherine M, Henning, Lars, Ketheesan, Natkunam, Kupz, Andreas

“…Comorbid type 2 diabetes poses a great challenge to the global control of tuberculosis. Here, we assessed the efficacy of metformin (MET), an antidiabetic…”
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The Effect of Tropical Temperatures on the Quality of RNA Extracted from Stabilized Whole-Blood Samples by Sarathkumara, Yomani D., Browne, Daniel J., Kelly, Ashton M., Pattinson, David J., Rush, Catherine M., Warner, Jeffrey, Proietti, Carla, Doolan, Denise L.

“…Whole-blood-derived transcriptional profiling is widely used in biomarker discovery, immunological research, and therapeutic development. Traditional molecular…”
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Mucosal delivery of ESX-1–expressing BCG strains provides superior immunity against tuberculosis in murine type 2 diabetes by Sathkumara, Harindra D., Muruganandah, Visai, Cooper, Martha M., Field, Matt A., Alim, Md Abdul, Brosch, Roland, Ketheesan, Natkunam, Govan, Brenda, Rush, Catherine M., Henning, Lars, Kupz, Andreas

“…Tuberculosis (TB) claims 1.5 million lives per year. This situation is largely due to the low efficacy of the only licensed TB vaccine, Bacillus…”
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Antibodies as clinical tools for tuberculosis by McIntyre, Sophie, Warner, Jeffrey, Rush, Catherine, Vanderven, Hillary A

“…Tuberculosis (TB) is a leading cause of morbidity and mortality worldwide. Global research efforts to improve TB control are hindered by insufficient…”
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Reversal of the TCR Stop Signal by CTLA-4 by Schneider, Helga, Downey, Jos, Smith, Andrew, Zinselmeyer, Bernd H, Rush, Catherine, Brewer, James M, Wei, Bin, Hogg, Nancy, Garside, Paul, Rudd, Christopher E

“…The coreceptor cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is pivotal in regulating the threshold of signals during T cell activation, although the…”
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Effect of savirin in the prevention of biofilm-related Staphylococcus aureus prosthetic joint infection by Pant, Narayan, Miranda-Hernandez, Socorro, Rush, Catherine, Warner, Jeffrey, Eisen, Damon P.

“…Background: Most of the arthroplasty surgery failure due to prosthetic joint infections (PJI) is caused by biofilm-associated Staphylococcus aureus . In a…”
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Non-Antimicrobial Adjuvant Therapy Using Ticagrelor Reduced Biofilm-Related Staphylococcus aureus Prosthetic Joint Infection by Pant, Narayan, Miranda-Hernandez, Socorro, Rush, Catherine, Warner, Jeffrey, Eisen, Damon P.

“…Background: Prosthetic joint infection (PJI), frequently caused by Staphylococcus aureus , leads to a significant arthroplasty failure rate. Biofilm is a…”
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Acute effects of exercise-induced muscle damage on sprint and change of direction performance: A systematic review and metaanalysis by Harrison, Drew C., Doma, Kenji, Rush, Catherine, Connor, Jonathan

“…The aim of this study is to determine the acute effects of resistance and plyometric training on sprint and change of direction (COD) performance in healthy…”
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Tropical fever in remote tropics: tuberculosis or melioidosis, it depends on the lab by Warner, Jeffrey, Rush, Catherine

“…Diagnostics tests used to identify the cause of infection using proteomics and genomics have revolutionised microbiology laboratories in recent times. However,…”
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Group G Streptococcus Induces an Autoimmune Carditis Mediated by Interleukin 17A and Interferon γ in the Lewis Rat Model of Rheumatic Heart Disease by Sikder, Suchandan, Williams, Natasha L, Sorenson, Alanna E, Alim, Md A, Vidgen, Miranda E, Moreland, Nicole J, Rush, Catherine M, Simpson, Robert S, Govan, Brenda L, Norton, Robert E, Cunningham, Madeleine W, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune sequelae of group A streptococcal infections. Here we provide experimental…”
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Migration of dendritic cells facilitates systemic dissemination of Burkholderia pseudomallei by Williams, Natasha L, Morris, Jodie L, Rush, Catherine M, Ketheesan, Natkunam

“…Burkholderia pseudomallei, the etiological agent for melioidosis, is an important cause of community-acquired sepsis in northern Australia and northeast…”
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Differential gene expression in the proximal neck of human abdominal aortic aneurysm by Biros, Erik, Moran, Corey S, Rush, Catherine M, Gäbel, Gabor, Schreurs, Charlotte, Lindeman, Jan H.N, Walker, Philip J, Nataatmadja, Maria, West, Malcolm, Holdt, Lesca M, Hinterseher, Irene, Pilarsky, Christian, Golledge, Jonathan

“…Abstract Objective Abdominal aortic aneurysm (AAA) represents a common cause of morbidity and mortality in elderly populations but the mechanisms involved in…”
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Angiopoietin-2 attenuates angiotensin II-induced aortic aneurysm and atherosclerosis in apolipoprotein E-deficient mice by Yu, Hongyou, Moran, Corey S., Trollope, Alexandra F., Woodward, Lynn, Kinobe, Robert, Rush, Catherine M., Golledge, Jonathan

“…Angiogenesis and inflammation are implicated in aortic aneurysm and atherosclerosis and regulated by angiopoietin-2 (Angpt2). The effect of Angpt2…”
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Modulation of Kinin B2 Receptor Signaling Controls Aortic Dilatation and Rupture in the Angiotensin II–Infused Apolipoprotein E–Deficient Mouse by Moran, Corey S, Rush, Catherine M, Dougan, Tammy, Jose, Roby J, Biros, Erik, Norman, Paul E, Gera, Lajos, Golledge, Jonathan

“…OBJECTIVE—Abdominal aortic aneurysm (AAA) is an important cause of mortality in older adults. Activity of the local kallikrein–kinin system may be important in…”
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Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm by Rush, Catherine, Nyara, Moses, Moxon, Joseph V, Trollope, Alexandra, Cullen, Bradford, Golledge, Jonathan

“…An animal model commonly used to investigate pathways and potential therapeutic interventions relevant to abdominal aortic aneurysm (AAA) involves subcutaneous…”
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Fenofibrate Increases High-Density Lipoprotein and Sphingosine 1 Phosphate Concentrations Limiting Abdominal Aortic Aneurysm Progression in a Mouse Model by Krishna, Smriti M, Seto, Sai Wang, Moxon, Joseph V, Rush, Catherine, Walker, Philip J, Norman, Paul E, Golledge, Jonathan

“…There are currently no acceptable treatments to limit progression of abdominal aortic aneurysm (AAA). Increased serum concentrations of high-density…”
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