Search Results - "Ruprecht, J"

Structural Mechanism of Transport of Mitochondrial Carriers by Ruprecht, J. J, Kunji, E.R.S

“…Members of the mitochondrial carrier family [solute carrier family 25 (SLC25)] transport nucleotides, amino acids, carboxylic acids, fatty acids, inorganic…”
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The SLC25 Mitochondrial Carrier Family: Structure and Mechanism by Ruprecht, Jonathan J., Kunji, Edmund R.S.

“…Members of the mitochondrial carrier family (SLC25) provide the transport steps for amino acids, carboxylic acids, fatty acids, cofactors, inorganic ions, and…”
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The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier by Ruprecht, Jonathan J., King, Martin S., Zögg, Thomas, Aleksandrova, Antoniya A., Pardon, Els, Crichton, Paul G., Steyaert, Jan, Kunji, Edmund R.S.

“…Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open…”
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The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology by Kunji, Edmund R. S., King, Martin S., Ruprecht, Jonathan J., Thangaratnarajah, Chancievan

“…Members of the mitochondrial carrier family (SLC25) transport a variety of compounds across the inner membrane of mitochondria. These transport steps provide…”
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Structural changes in the transport cycle of the mitochondrial ADP/ATP carrier by Ruprecht, Jonathan J, Kunji, Edmund RS

“…[Display omitted] •First structure of the matrix-open state of a mitochondrial ADP/ATP carrier has been solved.•Structure determined using protein inhibited by…”
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Wastewater effluents cause microbial community shifts and change trophic status by Ruprecht, J.E., Birrer, S.C., Dafforn, K.A., Mitrovic, S.M., Crane, S.L., Johnston, E.L., Wemheuer, F., Navarro, A., Harrison, A.J., Turner, I.L., Glamore, W.C.

“…•Microbes are sensitive to environmental stressors, such as wastewater pollution.•This study combined novel methods of microbial ecotoxicology in the field and…”
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Calcium-induced conformational changes of the regulatory domain of human mitochondrial aspartate/glutamate carriers by Thangaratnarajah, Chancievan, Ruprecht, Jonathan J., Kunji, Edmund R. S.

“…The transport activity of human mitochondrial aspartate/glutamate carriers is central to the malate–aspartate shuttle, urea cycle, gluconeogenesis and myelin…”
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Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism by Ruprecht, Jonathan J, Hellawell, Alex M, Harding, Marilyn, Crichton, Paul G, McCoy, Airlie J, Kunji, Edmund R S

“…The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix. The carrier cycles by an unresolved mechanism…”
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Substrate binding in the mitochondrial ADP/ATP carrier is a step-wise process guiding the structural changes in the transport cycle by Mavridou, Vasiliki, King, Martin S., Tavoulari, Sotiria, Ruprecht, Jonathan J., Palmer, Shane M., Kunji, Edmund R. S.

“…Mitochondrial ADP/ATP carriers import ADP into the mitochondrial matrix and export ATP to the cytosol to fuel cellular processes. Structures of the inhibited…”
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The transport mechanism of the mitochondrial ADP/ATP carrier by Kunji, Edmund R.S., Aleksandrova, Antoniya, King, Martin S., Majd, Homa, Ashton, Valerie L., Cerson, Elizabeth, Springett, Roger, Kibalchenko, Mikhail, Tavoulari, Sotiria, Crichton, Paul G., Ruprecht, Jonathan J.

“…The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix, which are key transport steps for oxidative…”
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Characterization of material around the centaur (2060) Chiron from a visible and near-infrared stellar occultation in 2011 by Sickafoose, A A, Bosh, A S, Emery, J P, Person, M J, Zuluaga, C A, Womack, M, Ruprecht, J D, Bianco, F B, Zangari, A M

“…ABSTRACT The centaur (2060) Chiron exhibits outgassing behaviour and possibly hosts a ring system. On 2011 November 29, Chiron occulted a fairly bright star…”
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Implications of bacterial mineralisation in aquatic ecosystem response models by Ruprecht, J.E., King, I.P., Dafforn, K.A., Mitrovic, S.M., Harrison, A.J., Birrer, S.C., Crane, S.L., Glamore, W.C.

“…•Novel application of microbial community ecotoxicology lab data to a water quality model.•Combined likelihood measures increase confidence in numerical model…”
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Electron crystallography reveals the structure of metarhodopsin I by Ruprecht, Jonathan J, Mielke, Thorsten, Vogel, Reiner, Villa, Claudio, Schertler, Gebhard FX

“…Rhodopsin is the prototypical G protein‐coupled receptor, responsible for detection of dim light in vision. Upon absorption of a photon, rhodopsin undergoes…”
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Assessing the validity and sensitivity of microbial processes within a hydrodynamic model by Ruprecht, J.E., King, I.P., Mitrovic, S.M., Dafforn, K.A., Miller, B.M., Deiber, M., Westhorpe, D.P., Hitchcock, J.N., Harrison, A.J., Glamore, W.C.

“…•Links between hydrodynamics and ecological responses via a multi-disciplinary study.•Functional representation of bacterial mineralisation improves…”
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Forest-water interactions in the changing environment of south-western Australia by Harper, Richard, Smettem, K. R. J., Ruprecht, J. K., Dell, B., Liu, Ning

“…Key message In a major Australian city, water supply has been decoupled from forests as a result of management and climate change. Water yield and quality are…”
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A novel real-world ecotoxicological dataset of pelagic microbial community responses to wastewater by Ruprecht, J. E., Glamore, W. C., Dafforn, K. A., Wemheuer, F., Crane, S. L., van Dorst, J., Johnston, E. L., Mitrovic, S. M., Turner, I. L., Ferrari, B. C., Birrer, S. C.

“…Real-world observational datasets that record and quantify pressure-stressor-response linkages between effluent discharges and natural aquatic systems are…”
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Preclearing hydrology of the Western Australia wheatbelt: target for the future? by Hatton, T.J, Ruprecht, J, George, R.J

“…The wheatbelt of Western Australia largely corresponds to a zone of ancient drainage, characterised by highly variable rainfall, long dry summers, low…”
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Estuarine dynamics and acid sulfate soil discharge: Quantifying a conceptual model by Ruprecht, J.E., Glamore, W.C., Rayner, D.S.

“…Over 170,000km2 of Acid Sulfate Soils (ASS) have been identified worldwide, with 65,000 km2 in Asia; 45,000km2 in Africa; 30,000km2 in Australia; 30,000km2 in…”
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The Role of Red Blood Cell Polymorphisms in Resistance and Susceptibility to Malaria by Lell, Bertrand, May, Jürgen, Schmidt-Ott, Ruprecht J., Lehman, Leopold G., Luckner, Doris, Greve, Bernhard, Matousek, Peter, Schmid, Daniela, Herbich, Klaus, Mockenhaupt, Frank P., Meyer, Christian G., Bienzle, Ulrich, Kremsner, Peter G.

“…In regions highly endemic for Plasmodium falciparum malaria, red cell polymorphisms that confer resistance to severe disease are widespread. Sickle cell trait,…”
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Structural mechanisms of mitochondrial uncoupling protein 1 regulation in thermogenesis by Jones, Scott A., Ruprecht, Jonathan J., Crichton, Paul G., Kunji, Edmund R.S.

“…Uncoupling protein 1 (UCP1, SLC25A7) is a mitochondrial carrier that facilitates thermogenesis in brown adipose tissue (BAT) by dissipating the protonmotive…”
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