Search Results - "Rupprecht, Harald"
-
1
Urinary peptidomic liquid biopsy for non-invasive differential diagnosis of chronic kidney disease
Published in Nephrology, dialysis, transplantation (28-02-2024)“…ABSTRACT Background and hypothesis Specific urinary peptides hold information on disease pathophysiology, which, in combination with artificial intelligence,…”
Get full text
Journal Article -
2
Recent Advances in Urinary Peptide and Proteomic Biomarkers in Chronic Kidney Disease: A Systematic Review
Published in International journal of molecular sciences (23-05-2023)“…Biomarker development, improvement, and clinical implementation in the context of kidney disease have been a central focus of biomedical research for decades…”
Get full text
Journal Article -
3
Microangiopathy in multiple myeloma: a case of carfilzomib-induced secondary thrombotic microangiopathy successfully treated with plasma exchange and complement inhibition
Published in BMC nephrology (19-06-2023)“…Thrombotic microangiopathy (TMA) is a potentially organ and life-threatening condition affecting patients with multiple myeloma (MM). Cases of…”
Get full text
Journal Article -
4
Naturally Occurring Human Urinary Peptides for Use in Diagnosis of Chronic Kidney Disease
Published in Molecular & cellular proteomics (01-11-2010)“…Because of its availability, ease of collection, and correlation with physiology and pathology, urine is an attractive source for clinical…”
Get full text
Journal Article -
5
Assessment and Risk Prediction of Chronic Kidney Disease and Kidney Fibrosis Using Non-Invasive Biomarkers
Published in International journal of molecular sciences (01-04-2024)“…Effective management of chronic kidney disease (CKD), a major health problem worldwide, requires accurate and timely diagnosis, prognosis of progression,…”
Get full text
Journal Article -
6
Non-Invasive Biomarkers for Diagnosis, Risk Prediction, and Therapy Guidance of Glomerular Kidney Diseases: A Comprehensive Review
Published in International journal of molecular sciences (01-03-2024)“…Effective management of glomerular kidney disease, one of the main categories of chronic kidney disease (CKD), requires accurate diagnosis, prognosis of…”
Get full text
Journal Article -
7
A Novel Urinary Proteomics Classifier for Non-Invasive Evaluation of Interstitial Fibrosis and Tubular Atrophy in Chronic Kidney Disease
Published in Proteomes (13-07-2021)“…Non-invasive urinary peptide biomarkers are able to detect and predict chronic kidney disease (CKD). Moreover, specific urinary peptides enable discrimination…”
Get full text
Journal Article -
8
Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a prospective multicentre cohort study
Published in The Lancet. Digital health (01-10-2022)“…The SARS-CoV-2 pandemic is a worldwide challenge. The CRIT-CoV-U pilot study generated a urinary proteomic biomarker consisting of 50 peptides (COV50), which…”
Get full text
Journal Article -
9
Identification and Validation of Urinary Biomarkers for Differential Diagnosis and Evaluation of Therapeutic Intervention in Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis
Published in Molecular & cellular proteomics (01-10-2009)“…Renal activity and smoldering disease is difficult to assess in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) because of renal scarring…”
Get full text
Journal Article -
10
Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy
Published in Kidney international (01-06-2005)“…Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. IgA nephropathy (IgAN) is the most common chronic glomerular disease in…”
Get full text
Journal Article -
11
Molecular Mapping of Urinary Complement Peptides in Kidney Diseases
Published in Proteomes (13-12-2021)“…Defective complement activation has been associated with various types of kidney disease. This led to the hypothesis that specific urine complement fragments…”
Get full text
Journal Article -
12
Proteomic patterns established with capillary electrophoresis and mass spectrometry for diagnostic purposes
Published in Kidney international (01-06-2004)“…Proteomic patterns established with capillary electrophoresis and mass spectrometry for diagnostic purposes. Proteomics applied in large scale may provide a…”
Get full text
Journal Article -
13
ANCA-associated vasculitis with renal involvement: an outcome analysis
Published in Nephrology, dialysis, transplantation (01-06-2004)“…Background. The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides are a group of heterogeneous diseases. This study was undertaken to…”
Get full text
Journal Article -
14
"Vodka energy": too much for the adolescent nephron?
Published in Pediatrics (Evanston) (01-07-2011)“…We report here the case of a 17-year-old boy who suffered acute renal failure after consuming 3 L of energy drink (ED) in combination with 1 L of vodka…”
Get full text
Journal Article -
15
Thromboembolic events as a complication of antineutrophil cytoplasmic antibody–associated vasculitis
Published in Arthritis and rheumatism (15-02-2006)Get full text
Journal Article -
16
Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells
Published in Biological chemistry (01-05-2007)“…Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis. Studies have established a direct role for nitric oxide (NO) in…”
Get more information
Journal Article -
17
Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells
Published in Kidney international (01-08-2002)“…Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells. Nitric oxide (NO) exerts complex regulatory actions on mesangial cell (MC)…”
Get full text
Journal Article -
18
Adverse Drug Events in Patients with Chronic Kidney Disease Associated with Multiple Drug Interactions and Polypharmacy
Published in Drugs & aging (01-05-2020)“…Background and Purpose Chronic kidney disease (CKD) is associated with adverse drug events due to medication errors and the risks of polypharmacy. The aim of…”
Get full text
Journal Article -
19
The effect of sevelamer on tacrolimus target levels
Published in Transplantation (15-09-2005)Get full text
Journal Article -
20
Nitric oxide inhibits growth of glomerular mesangial cells: Role of the transcription factor EGR-1
Published in Kidney international (01-01-2000)“…In previous studies, we found a close link of early growth response gene-1 (Egr-1) expression to mesangial cell (MC) proliferation. Antiproliferative agents…”
Get full text
Journal Article