Search Results - "Ruppelt, Dominik"

The antimicrobial fibupeptide lugdunin forms water-filled channel structures in lipid membranes by Ruppelt, Dominik, Trollmann, Marius F. W., Dema, Taulant, Wirtz, Sebastian N., Flegel, Hendrik, Mönnikes, Sophia, Grond, Stephanie, Böckmann, Rainer A., Steinem, Claudia

“…Recently, a novel cyclo-heptapeptide composed of alternating d , l -amino acids and a unique thiazolidine heterocycle, called lugdunin, was discovered, which…”
Get full text

The microbiome-derived antibacterial lugdunin acts as a cation ionophore in synergy with host peptides by Berscheid, Anne, Straetener, Jan, Schilling, Nadine A, Ruppelt, Dominik, Konnerth, Martin C, Schittek, Birgit, Krismer, Bernhard, Peschel, Andreas, Steinem, Claudia, Grond, Stephanie, Brötz-Oesterhelt, Heike

“…Lugdunin is a microbiome-derived antibacterial agent with good activity against Gram-positive pathogens and in animal models of nose colonization and skin…”
Get full text

Total synthesis and mechanism of action of the antibiotic armeniaspirol A by Arisetti, Nanaji, Fuchs, Hazel L. S, Coetzee, Janetta, Orozco, Manuel, Ruppelt, Dominik, Bauer, Armin, Heimann, Dominik, Kuhnert, Eric, Bhamidimarri, Satya P, Bafna, Jayesh A, Hinkelmann, Bettina, Eckel, Konstantin, Sieber, Stephan A, Müller, Peter P, Herrmann, Jennifer, Müller, Rolf, Winterhalter, Mathias, Steinem, Claudia, Brönstrup, Mark

“…Emerging antimicrobial resistance urges the discovery of antibiotics with unexplored, resistance-breaking mechanisms. Armeniaspirols represent a novel class of…”
Get full text