Search Results - "Rupp, Niels"

Automated Gleason grading of prostate cancer tissue microarrays via deep learning by Arvaniti, Eirini, Fricker, Kim S., Moret, Michael, Rupp, Niels, Hermanns, Thomas, Fankhauser, Christian, Wey, Norbert, Wild, Peter J., Rüschoff, Jan H., Claassen, Manfred

“…The Gleason grading system remains the most powerful prognostic predictor for patients with prostate cancer since the 1960s. Its application requires…”
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Comparison of the PI-RADS 2.1 scoring system to PI-RADS 2.0: Impact on diagnostic accuracy and inter-reader agreement by Hötker, Andreas M, Blüthgen, Christian, Rupp, Niels J, Schneider, Aurelia F, Eberli, Daniel, Donati, Olivio F

“…Purpose To assess the value of the PI-RADS 2.1 scoring system in the detection of prostate cancer on multiparametric MRI in comparison to the standard PI-RADS…”
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Pleomorphic adenoma with PLAG1 fusion as an isolated kidney mass: lessons learned from a challenging case by Lobo, João, Rechsteiner, Markus, Rupp, Niels J, Ostertag, Helmut, Moch, Holger

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Genomic alterations and diagnosis of renal cancer by Zhang, Xingming, Bolck, Hella A., Rupp, Niels J., Moch, Holger

“…The application of molecular profiling has made substantial impact on the classification of urogenital tumors. Therefore, the 2022 World Health Organization…”
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ALK-rearranged renal cell carcinoma—different morphological faces of a rare tumor: Editorial to Hang et al.: ALK-rearranged renal cell carcinoma with a novel PLEKHA7-ALK translocation and metanephric adenoma-like morphology by Rupp, Niels J., Moch, Holger

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Molecular Profiling of Mammary Analog Secretory Carcinoma Revealed a Subset of Tumors Harboring a Novel ETV6-RET Translocation: Report of 10 Cases by Skalova, Alena, Vanecek, Tomas, Martinek, Petr, Weinreb, Ilan, Stevens, Todd M, Simpson, Roderick H.W, Hyrcza, Martin, Rupp, Niels J, Baneckova, Martina, Michal, Michael, Slouka, David, Svoboda, Tomas, Metelkova, Alena, Etebarian, Arghavan, Pavelka, Jaroslav, Potts, Steven J, Christiansen, Jason, Steiner, Petr, Michal, Michal

“…ETV6 gene abnormalities are well described in tumor pathology. Many fusion partners of ETV6 have been reported in a variety of epithelial, mesenchymal, and…”
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Microcribriform Adenocarcinoma of Salivary Glands: A Unique Tumor Entity Characterized by an SS18::ZBTB7A Fusion by Weinreb, Ilan, Hahn, Elan, Dickson, Brendan C., Rooper, Lisa M., Rupp, Niels J., Freiberger, Sandra N., Lubin, Daniel, Gagan, Jeffrey, Bishop, Justin A.

“…The landscape of salivary gland carcinomas is ever-changing, with a growing list of new tumors and newly elucidated variants of well-known tumor entities. The…”
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Extensive Histological Sampling following Focal Therapy of Clinically Significant Prostate Cancer with High Intensity Focused Ultrasound by Mortezavi, Ashkan, Krauter, Johanna, Gu, Alexander, Sonderer, Julian, Bruhin, Julia, Reeve, Kelly A, Held, Leonhard, Donati, Olivio F, Rupp, Niels J, Moch, Holger, Sulser, Tullio, Eberli, Daniel

“…Clinically significant, localized prostate cancer is currently treated with whole gland therapy. This approach is effective but associated with genitourinary…”
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NCOA4-RET and TRIM27-RET Are Characteristic Gene Fusions in Salivary Intraductal Carcinoma, Including Invasive and Metastatic Tumors: Is “Intraductal” Correct? by Skálová, Alena, Ptáková, Nikola, Santana, Thalita, Agaimy, Abbas, Ihrler, Stephan, Uro-Coste, Emmanuelle, Thompson, Lester D.R, Bishop, Justin A, Baněčkova, Martina, Rupp, Niels J, Morbini, Patrizia, de Sanctis, Stefano, Schiavo-Lena, Marco, Vanecek, Tomas, Michal, Michal, Leivo, Ilmo

“…Intraductal carcinoma (IC) is the new WHO designation for tumors previously encompassed by “low-grade cribriform cystadenocarcinoma” and “low-grade salivary…”
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Diagnostic Accuracy of Multiparametric Magnetic Resonance Imaging and Fusion Guided Targeted Biopsy Evaluated by Transperineal Template Saturation Prostate Biopsy for the Detection and Characterization of Prostate Cancer by Mortezavi, Ashkan, Märzendorfer, Olivia, Donati, Olivio F., Rizzi, Gianluca, Rupp, Niels J., Wettstein, Marian S., Gross, Oliver, Sulser, Tullio, Hermanns, Thomas, Eberli, Daniel

“…We evaluated the diagnostic accuracy of multiparametric magnetic resonance imaging and multiparametric magnetic resonance imaging/transrectal ultrasound fusion…”
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SalvGlandDx – a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets by Freiberger, Sandra N., Brada, Muriel, Fritz, Christine, Höller, Sylvia, Vogetseder, Alexander, Horcic, Milo, Bihl, Michel, Michal, Michal, Lanzer, Martin, Wartenberg, Martin, Borner, Urs, Bode, Peter K., Broglie, Martina A., Rordorf, Tamara, Morand, Grégoire B., Rupp, Niels J.

“…•SalvGlandDx includes 27 genes known to be involved in salivary gland neoplasms•Can be applied to FFPE histological and cytological (cell block)…”
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MRI-based monitoring of prostate cancer after HIFU: Inter-reader agreement and diagnostic performance of the PI-FAB score by Pausch, Antonia M., Elsner, Clara, Rupp, Niels J., Eberli, Daniel, Hötker, Andreas M.

“…•Need for standardized monitoring methodology after focal prostate treatment.•Clinical application of MRI-based PI-FAB score for follow-up after HIFU…”
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Risk factors for prostate cancer in men with false-negative mpMRI: A retrospective single center cohort study of image quality scores and clinical parameters by Pausch, Antonia M., Ghafoor, Soleen, Kluckert, Jonas, Rupp, Niels J., Eberli, Daniel, Hötker, Andreas M.

“…•Analysis of missed PCa and csPCa in men with prior negative mpMRI.•Significance of MR image quality scores (PI-QUAL, PSHS) and clinical parameters.•Lower…”
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High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification by Zhu, Yi, Weiss, Tobias, Zhang, Qiushi, Sun, Rui, Wang, Bo, Yi, Xiao, Wu, Zhicheng, Gao, Huanhuan, Cai, Xue, Ruan, Guan, Zhu, Tiansheng, Xu, Chao, Lou, Sai, Yu, Xiaoyan, Gillet, Ludovic, Blattmann, Peter, Saba, Karim, Fankhauser, Christian D., Schmid, Michael B., Rutishauser, Dorothea, Ljubicic, Jelena, Christiansen, Ailsa, Fritz, Christine, Rupp, Niels J., Poyet, Cedric, Rushing, Elisabeth, Weller, Michael, Roth, Patrick, Haralambieva, Eugenia, Hofer, Silvia, Chen, Chen, Jochum, Wolfram, Gao, Xiaofei, Teng, Xiaodong, Chen, Lirong, Zhong, Qing, Wild, Peter J., Aebersold, Ruedi, Guo, Tiannan

“…Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable resource for clinical and biomarker research. Here, we developed a…”
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Eosinophilic solid and cystic renal cell carcinoma and renal cell carcinomas with TFEB alterations: a comparative study by Lobo, João, Rechsteiner, Markus, Helmchen, Birgit M, Rupp, Niels J, Weber, Achim, Moch, Holger

“…Aims Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) is a recently described renal tumour entity with frequent cytokeratin (CK)20 positivity,…”
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Outcome-oriented clinicopathological reappraisal of sinonasal adenoid cystic carcinoma with broad morphological spectrum and high MYB::NFIB prevalence by Mauthe, Tina, Meerwein, Christian M., Holzmann, David, Soyka, Michael B., Mueller, Simon A., Held, Ulrike, Freiberger, Sandra N., Rupp, Niels J.

“…Adenoid cystic carcinoma (AdCC) is a salivary gland neoplasm that infrequently appears in the sinonasal region. The aim of this study was to evaluate the…”
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Measurement variations of MRI and CT in the assessment of tumor depth of invasion in oral cancer: A retrospective study by Waech, Tobias, Pazahr, Shila, Guarda, Vittoria, Rupp, Niels J., Broglie, Martina A., Morand, Grégoire B.

“…In oral squamous cell carcinoma (OSCC), depth of invasion (DOI) is an important predictive, prognostic, and staging parameter. While it is known that DOI can…”
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Discovery of Novel TULP4/ACTN4/EWSR1/ACTB::MYB and ESRRG::DNM3 Fusions Expands Molecular Landscape of Adenoid Cystic Carcinoma Beyond Fusions Between MYB/MYBL1 and NFIB Genes by Skálová, Alena, Klubíčková, Natálie, Bradová, Martina, Agaimy, Abbas, Rupp, Niels J, Damjanov, Ivan, Kolnikova, Georgina, Martínek, Petr, Šteiner, Petr, Grossmann, Petr, Vaněček, Tomas, Michal, Michal, Leivo, Ilmo

“…Adenoid cystic carcinoma (AdCC) is one of the most common salivary gland malignancies and occurs in all major and minor salivary gland and seromucous gland…”
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MRI-based radiomics for predicting histology in malignant salivary gland tumors: methodology and “proof of principle” by Khodabakhshi, Zahra, Motisi, Laura, Bink, Andrea, Broglie, Martina A., Rupp, Niels J., Fleischmann, Maximilian, von der Grün, Jens, Guckenberger, Matthias, Tanadini-Lang, Stephanie, Balermpas, Panagiotis

“…Defining the exact histological features of salivary gland malignancies before treatment remains an unsolved problem that compromises the ability to tailor…”
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Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins by Shao, Wenguang, Guo, Tiannan, Toussaint, Nora C., Xue, Peng, Wagner, Ulrich, Li, Li, Charmpi, Konstantina, Zhu, Yi, Wu, Jianmin, Buljan, Marija, Sun, Rui, Rutishauser, Dorothea, Hermanns, Thomas, Fankhauser, Christian Daniel, Poyet, Cedric, Ljubicic, Jelena, Rupp, Niels, Rüschoff, Jan H., Zhong, Qing, Beyer, Andreas, Ji, Jiafu, Collins, Ben C., Liu, Yansheng, Rätsch, Gunnar, Wild, Peter J., Aebersold, Ruedi

“…Deterioration of biomolecules in clinical tissues is an inevitable pre-analytical process, which affects molecular measurements and thus potentially confounds…”
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