Search Results - "Rupasinghe, H. P. Vasantha"
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Industrial Hemp ( Cannabis sativa subsp. sativa ) as an Emerging Source for Value-Added Functional Food Ingredients and Nutraceuticals
Published in Molecules (Basel, Switzerland) (07-09-2020)“…Industrial hemp ( L., Cannabaceae) is an ancient cultivated plant originating from Central Asia and historically has been a multi-use crop valued for its…”
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Flavonoid bioavailability and attempts for bioavailability enhancement
Published in Nutrients (28-08-2013)“…Flavonoids are a group of phytochemicals that have shown numerous health effects and have therefore been studied extensively. Of the six common food flavonoid…”
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Special Issue "Flavonoids and Their Disease Prevention and Treatment Potential": Recent Advances and Future Perspectives
Published in Molecules (Basel, Switzerland) (16-10-2020)“…In recent years, the interest in flavonoids as dietary bioactives to prevent human diseases, as well as their candidacy as pharmaceutical leads, has…”
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Carvacrol exhibits rapid bactericidal activity against Streptococcus pyogenes through cell membrane damage
Published in Scientific reports (15-01-2021)“…Streptococcus pyogenes is an important human pathogen worldwide. The identification of natural antibacterial phytochemicals has renewed interest due to the…”
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Potentials of Natural Preservatives to Enhance Food Safety and Shelf Life: A Review
Published in TheScientificWorld (23-09-2022)“…Food-borne illnesses are a significant concern for consumers, the food industry, and food safety authorities. Natural preservatives are very crucial for…”
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Regulation of Nrf2/ARE Pathway by Dietary Flavonoids: A Friend or Foe for Cancer Management?
Published in Antioxidants (01-10-2020)“…The nuclear factor erythroid 2-related factor 2 (Nrf2)/antioxidant response element (ARE) pathway is an important cell signaling mechanism in maintaining redox…”
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Bactericidal and Anti-Biofilm Activity of Ethanol Extracts Derived from Selected Medicinal Plants against Streptococcus pyogenes
Published in Molecules (Basel, Switzerland) (24-03-2019)“…There is a growing interest in medicinal plants which have been traditionally used for the treatment of human infections. This study assessed 14 ethanol…”
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Plant Polyphenols as Chemopreventive Agents for Lung Cancer
Published in International journal of molecular sciences (19-08-2016)“…Lung cancer may be prevented by a diet rich in fruits and vegetables as they are enriched with dietary antioxidant polyphenols, such as flavonoids,…”
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Chemopreventive Effect of Dietary Anthocyanins against Gastrointestinal Cancers: A Review of Recent Advances and Perspectives
Published in International journal of molecular sciences (08-09-2020)“…Anthocyanins are a group of dietary polyphenols, abundant mainly in fruits and their products. Dietary interventions of anthocyanins are being studied…”
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Optimization of the Extraction of Proanthocyanidins from Grape Seeds Using Ultrasonication-Assisted Aqueous Ethanol and Evaluation of Anti-Steatosis Activity In Vitro
Published in Molecules (Basel, Switzerland) (17-02-2022)“…Conventional extraction methods of proanthocyanidins (PAC) are based on toxic organic solvents, which can raise concerns about the use of extracts in…”
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In Vitro Anti-Inflammatory Properties of Selected Green Leafy Vegetables
Published in Biomedicines (19-11-2018)“…The study investigated the anti-inflammatory activity of the hydro methanolic extract of six leafy vegetables, namely , , , , , and . The anti-inflammatory…”
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Cyanidin-3- O -Glucoside-Rich Haskap Berry Administration Suppresses Carcinogen-Induced Lung Tumorigenesis in A/JCr Mice
Published in Molecules (Basel, Switzerland) (22-08-2020)“…In our previous study, we demonstrated that cyanidin-3- -glucoside (C3G)-rich haskap ( L.) berry extracts can attenuate the carcinogen-induced DNA damage in…”
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Genistein and Procyanidin B2 Reduce Carcinogen-Induced Reactive Oxygen Species and DNA Damage through the Activation of Nrf2/ARE Cell Signaling in Bronchial Epithelial Cells In Vitro
Published in International journal of molecular sciences (01-02-2023)“…Cancer is one of the leading causes of death worldwide. Chemotherapy and radiation therapy are currently providing the basis for cancer therapies, although…”
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Molecular Mechanisms of Inhibition of Streptococcus Species by Phytochemicals
Published in Molecules (Basel, Switzerland) (17-02-2016)“…This review paper summarizes the antibacterial effects of phytochemicals of various medicinal plants against pathogenic and cariogenic streptococcal species…”
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Fatty acid esters of phloridzin induce apoptosis of human liver cancer cells through altered gene expression
Published in PloS one (17-09-2014)“…Phloridzin (phlorizin or phloretin 2'-O-glucoside) is known for blocking intestinal glucose absorption. We have investigated the anticarcinogenic effect of…”
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Antidiabetic, Antiglycation, and Antioxidant Activities of Ethanolic Seed Extract of Passiflora edulis and Piceatannol In Vitro
Published in Molecules (Basel, Switzerland) (24-06-2022)“…The objective of this work was to investigate the antidiabetic, antiglycation, and antioxidant potentials of ethanolic extract of seeds of Brazilian Passiflora…”
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Role of Antioxidant Vitamins and Other Micronutrients on Regulations of Specific Genes and Signaling Pathways in the Prevention and Treatment of Cancer
Published in International journal of molecular sciences (23-03-2023)“…Cancer is an escalating global issue, with 19.3 million new cases and 9.9 million deaths in 2020. Therefore, effective approaches to prevent cancer are…”
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Proanthocyanidins-Based Synbiotics as a Novel Strategy for Nonalcoholic Fatty Liver Disease (NAFLD) Risk Reduction
Published in Molecules (Basel, Switzerland) (01-02-2024)“…Nonalcoholic fatty liver disease (NAFLD), the most common liver disease worldwide, is a spectrum of liver abnormalities ranging from steatosis to nonalcoholic…”
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Recent Advances in Phytochemical-Based Topical Applications for the Management of Eczema: A Review
Published in International journal of molecular sciences (15-05-2024)“…Eczema (atopic dermatitis, AD) is a skin disease characterized by skin barrier dysfunction due to various factors, including genetics, immune system…”
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Sea Cucumber and Blueberry Extracts Suppress Inflammation and Reduce Acute Lung Injury through the Regulation of NF-κB/MAPK/JNK Signaling Pathway in Lipopolysaccharide-Treated C57BL/6 Mice
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Acute lung injury (ALI) represents a life-threatening condition with high morbidity and mortality despite modern mechanical ventilators and multiple…”
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