Search Results - "Ruoho, A E"

Lack of sigma-1 receptor exacerbates ALS progression in mice by Mavlyutov, T.A, Epstein, M.L, Verbny, Y.I, Huerta, M.S, Zaitoun, I, Ziskind-Conhaim, L, Ruoho, A.E

“…Highlights ► Knockout of S1R in the SOD1G93A mouse model of ALS significantly reduces longevity. ► MN of mice lacking S1R exhibit increased excitability. ► S1R…”
Get full text

The sigma-1 receptor is enriched in postsynaptic sites of C-terminals in mouse motoneurons. An anatomical and behavioral study by Mavlyutov, T.A, Epstein, M.L, Andersen, K.A, Ziskind-Conhaim, L, Ruoho, A.E

“…Abstract The sigma-1 receptor regulates various ion channel activity and possesses protein chaperone function. Using an antibody against the full sequence of…”
Get full text

Development of the sigma-1 receptor in C-terminals of motoneurons and colocalization with the N , N ′-dimethyltryptamine forming enzyme, indole- N -methyl transferase by Mavlyutov, T.A, Epstein, M.L, Liu, P, Verbny, Y.I, Ziskind-Conhaim, L, Ruoho, A.E

“…Abstract The function of the sigma-1 receptor (S1R) has been linked to modulating the activities of ion channels and G-protein-coupled receptors (GPCR). In the…”
Get full text

N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux by Torres, B, Ruoho, A.E

“…Highlights • The VMAT2 N-terminus enables sequestration. • A GST-construct of the N-terminus undergoes phosphorylation by PKC at serines 15 and/or 18. • The…”
Get full text

An investigation into the synthesis and characterization of new optically active poly(ester-imide) thermoplastic elastomers, derived from N, N′-(pyromellitoyl)-bis- l-leucine, synthetic diols and polyethyleneglycol-diol (PEG-200) by Hajipour, A.R., Zahmatkesh, S., Ruoho, A.E.

“…Pyromellitic dianhydride ( 1) was reacted with l-leucine ( 2) to result [ N, N′-(pyromellitoyl)-bis- l-leucine diacid] ( 3). This compound ( 3) was converted…”
Get full text

Structure of the adenylyl cyclase catalytic core by Zhang, Gongyi, Liu, Yu, Ruoho, Arnold E, Hurley, James H

“…Mammalian adenylyl cyclases contain two conserved regions, C1 and C2, which are responsible for forskolin- and G-protein-stimulated catalysis. The structure of…”
Get full text

Inhibition of plasma membrane monoamine transporters by β-ketoamphetamines by Cozzi, Nicholas V, Sievert, Michael K, Shulgin, Alexander T, Jacob, Peyton, Ruoho, Arnold E

“…Methcathinone and methylone, the β-ketone analogues of methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA), respectively, were tested for…”
Get full text

Insulin-regulated Glucose Uptake in Rat Adipocytes Is Mediated by Two Transporter Isoforms Present in at Least Two Vesicle Populations by Zorzano, A, Wilkinson, W, Kotliar, N, Thoidis, G, Wadzinkski, B E, Ruoho, A E, Pilch, P F

“…We have recently described a monoclonal antibody (1F8) that recognizes a form of glucose transporter unique to fat and muscle (James, D. E., Brown, R.,…”
Get full text

Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers by FOLEY, K. F, VAN DORT, M. E, SIEVERT, M. K, RUOHO, A. E, COZZI, N. V

“…Meta-hydroxyephedrine (HED) comprises four stereoisomers consisting of two enantiomeric pairs related to ephedrine and pseudoephedrine. HED is transported into…”
Get full text

Supported Bismuth(III) Nitrate on Silica Sulfuric Acid as Useful Reagent for Nitration of Aromatic Compounds under Solvent-Free Conditions by Hajipour, A. R., Zarei, A., Ruoho, A. E.

Get full text

The catecholamine binding site of the beta-adrenergic receptor is formed by juxtaposed membrane-spanning domains by Wong, S K, Slaughter, C, Ruoho, A E, Ross, E M

“…The catecholamine binding domain of the turkey erythrocyte beta-adrenergic receptor was mapped by determining the sites of covalent labeling of the purified…”
Get full text

METHYLTRIPHENYLPHOSPHONIUM PEROXYDISULFATE AND IODINE AS MILD REAGENTS FOR THE IODINATION OF ACTIVATED AROMATIC COMPOUNDS by Hajipour, Abdol R., Ruoho, A. E.

Get full text

Phorbol Ester Induces Desensitization of Adenylate Cyclase and Phosphorylation of the β -adrenergic Receptor in Turkey Erythrocytes by Kelleher, Daniel J., Pessin, Jeffrey E., Ruoho, Arnold E., Johnson, Gary L.

“…Incubation of turkey erythrocytes with the phorbol ester phorbol 12-myristate 13-acetate (PMA) results in a dose- and time-dependent desensitization of…”
Get full text

(125I)Iodoazidococaine, a Photoaffinity Label for the Haloperidol- Sensitive Sigma Receptor by Kahoun, John R., Ruoho, Arnold E.

“…A carrier-free radioiodinated cocaine photoaffinity label, (-)-3-(125I)iodo-4-azidococaine [(125I)IACoc], has been synthesized and used as a probe for…”
Get full text

Hydrophobically modified poly (acrylic acid) using calix[4]arene derivative. Ionophoric properties and extraction abilities toward alkali metal cations by Hajipour, A. R., Habibi, S., Ruoho, A. E.

“…p‐t‐Butyl calix[4]arene diol (distal cone) (1) was grafted with poly (acrylic acid) (PAA) to obtain hydrophobically modified PAA (PAA‐C) bearing calixarene…”
Get full text

A novel method for sulfonation of aromatic rings with silica sulfuric acid by Hajipour, Abdol R., Mirjalili, Bi Bi F., Zarei, Amin, Khazdooz, Leila, Ruoho, A.E.

“…[Display omitted] Direct and chemoselective sulfonation of aromatic compounds with silica sulfuric acid in 1,2-dichloeoethane or under solvent-free conditions…”
Get full text

Fatty acyl CoA esters as regulators of cell metabolism by Shrago, E., Woldegiorgis, G., Ruoho, A.E., DiRusso, C.C.

“…Long chain fatty acyl CoA esters have the ability to interact with certain proteins and thereby serve as effectors in cell metabolism. In particular, they can…”
Get full text

N-glycosylation in expression and function of beta-adrenergic receptors by George, S T, Ruoho, A E, Malbon, C C

“…Through the use of specific staining and the analysis of the interaction of pure beta-adrenergic receptor of S49 mouse lymphoma cells with lectins immobilized…”
Get full text

Catalytic mechanism of the adenylyl and guanylyl cyclases: modeling and mutational analysis by Liu, Y, Ruoho, A.E, Rao, V.D, Hurley, J.H

“…The adenylyl and guanylyl cyclases catalyze the formation of 3',5'-cyclic adenosine or guanosine monophosphate from the corresponding nucleoside…”
Get full text

Characterization and crystallization of a minimal catalytic core domain from mammalian type II adenylyl cyclase by Zhang, Gongyi, Liu, Yu, Qin, Jun, Vo, Binh, Tang, Wei‐Jen, Ruoho, Arnold E., Hurley, James H.

“…Adenylyl cyclases play a pivotal role in signal transduction by carrying out the regulated synthesis of cyclic AMP. The nine cloned mammalian adenylyl cyclases…”
Get full text