Search Results - "Runz, Josefine"
-
1
TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent activation of cytotoxic immune cells for the treatment of cancer
Published in Journal for immunotherapy of cancer (01-07-2022)“…BackgroundRecombinant interleukin-2 (IL-2, aldesleukin) is an approved cancer immunotherapy but causes severe toxicities including cytokine storm and vascular…”
Get full text
Journal Article -
2
Clinical implications of AGR2 in primary prostate cancer: Results from a large-scale study
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01-04-2024)“…Human anterior gradient-2 (AGR2) has been implicated in carcinogenesis of various solid tumours, but the expression data in prostate cancer are contradictory…”
Get full text
Journal Article -
3
TransCon IL-2 β/γ, a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 analog, demonstrates improved pharmacokinetics and profound expansion of cytotoxic immune cells in non-human primates
Published in Journal of clinical oncology (01-06-2022)“…2563 Background: Recombinant interleukin-2 (IL-2, aldesleukin) is an approved cancer immunotherapy but causes severe side effects including cytokine release…”
Get full text
Journal Article