Search Results - "Runyan, Avery"
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PAC1 receptor-mediated clearance of tau in postsynaptic compartments attenuates tau pathology in mouse brain
Published in Science translational medicine (26-05-2021)“…Accumulation of pathological tau in synapses has been identified as an early event in Alzheimer's disease (AD) and correlates with cognitive decline in…”
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Journal Article -
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5-HT4 receptor agonists treatment reduces tau pathology and behavioral deficit in the PS19 mouse model of tauopathy
Published in Frontiers in cellular neuroscience (04-04-2024)“…Accumulation of tau in synapses in the early stages of Alzheimer's disease (AD) has been shown to cause synaptic damage, synaptic loss, and the spread of tau…”
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Journal Article -
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Modified Roller Tube Method for Precisely Localized and Repetitive Intermittent Imaging During Long-term Culture of Brain Slices in an Enclosed System
Published in Journal of visualized experiments (28-12-2017)“…Cultured rodent brain slices are useful for studying the cellular and molecular behavior of neurons and glia in an environment that maintains many of their…”
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Journal Article -
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Modulation of the Immunoproteasome Affects Pathological Tau Aggregation in Alzheimer’s Disease
Published in Alzheimer's & dementia (01-12-2023)“…Background The Immunoproteasome is a dynamic system found in microglia that is induced under inflammatory conditions and previously hypothesized to be…”
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Journal Article -
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Basic Science and Pathogenesis - Part 2
Published in Alzheimer's & dementia (01-12-2023)“…The Immunoproteasome is a dynamic system found in microglia that is induced under inflammatory conditions and previously hypothesized to be causative of…”
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Journal Article -
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Intranasal Administration of Oxytocin Attenuates Social Recognition Deficits and Increases Prefrontal Cortex Inhibitory Postsynaptic Currents following Traumatic Brain Injury
Published in eNeuro (01-05-2021)“…Pediatric traumatic brain injury (TBI) results in heightened risk for social deficits that can emerge during adolescence and adulthood. A moderate TBI in male…”
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Journal Article -
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Social Behavior Deficits in Adolescence following Neonate Traumatic Brain Injury
Published 01-01-2019“…Traumatic brain injury early in life can lead to multiple long-term consequences including deficits in social behavior. We found neonate brain-injured rats…”
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Dissertation -
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