Search Results - "Runwal, Gautam"

LC3-positive structures are prominent in autophagy-deficient cells by Runwal, Gautam, Stamatakou, Eleanna, Siddiqi, Farah H., Puri, Claudia, Zhu, Ye, Rubinsztein, David C.

“…Autophagy is an evolutionarily conserved process across eukaryotes that degrades cargoes like aggregate-prone proteins, pathogens, damaged organelles and…”
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The role of α-synuclein in exocytosis by Runwal, Gautam M., Edwards, Robert H.

“…The pathogenesis of degeneration in Parkinson's disease (PD) remains poorly understood but multiple lines of evidence have converged on the presynaptic protein…”
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A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy by Puri, Claudia, Manni, Marco M., Vicinanza, Mariella, Hilcenko, Christine, Zhu, Ye, Runwal, Gautam, Stamatakou, Eleanna, Menzies, Fiona M., Mamchaoui, Kamel, Bitoun, Marc, Rubinsztein, David C.

“…Autophagy involves engulfment of cytoplasmic contents by double-membraned autophagosomes, which ultimately fuse with lysosomes to enable degradation of their…”
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Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy by Moreau, Kevin, Ghislat, Ghita, Hochfeld, Warren, Renna, Maurizio, Zavodszky, Eszter, Runwal, Gautam, Puri, Claudia, Lee, Shirley, Siddiqi, Farah, Menzies, Fiona M., Ravikumar, Brinda, Rubinsztein, David C.

“…Autophagy is an important degradation pathway, which is induced after starvation, where it buffers nutrient deprivation by recycling macromolecules in…”
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The Membrane Interactions of Synuclein: Physiology and Pathology by Runwal, Gautam, Edwards, Robert H

“…Specific proteins accumulate in neurodegenerative disease, and human genetics has indicated a causative role for many. In most cases, however, the mechanisms…”
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Autophagy in childhood neurological disorders by Zhu, Ye, Runwal, Gautam, Obrocki, Pawel, Rubinsztein, David C

“…Autophagy is a tightly modulated lysosomal degradation pathway. Genetic disorders of autophagy during nervous system development may lead to developmental…”
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