Search Results - "Runtsch, Leander"
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Structure and mechanism of the RNA dependent RNase Cas13a from Rhodobacter capsulatus
Published in Communications biology (20-01-2022)“…Cas13a are single-molecule effectors of the Class II, Type VI family of CRISPR-Cas systems that are part of the bacterial and archaeal defense systems. These…”
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Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line
Published in Clinical epigenetics (11-09-2022)“…Azacytidine (AzaC) and decitabine (AzadC) are cytosine analogs that covalently trap DNA methyltransferases, which place the important epigenetic mark…”
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A Click‐Chemistry‐Based Enrichable Crosslinker for Structural and Protein Interaction Analysis by Mass Spectrometry
Published in Chembiochem : a European journal of chemical biology (15-01-2020)“…Mass spectrometry is the method of choice for the characterisation of proteomes. Most proteins operate in protein complexes, in which their close association…”
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Comparative Nucleosomal Reactivity of 5‐Formyl‐Uridine and 5‐Formyl‐Cytidine
Published in Chemistry : a European journal (06-09-2021)“…5‐Formyl‐deoxyuridine (fdU) and 5‐formyl‐deoxycytidine (fdC) are formyl‐containing nucleosides that are created by oxidative stress in differentiated cells…”
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Azobenzene-based inhibitors of human carbonic anhydrase II
Published in Beilstein journal of organic chemistry (07-07-2015)“…Aryl sulfonamides are a widely used drug class for the inhibition of carbonic anhydrases. In the context of our program of photochromic pharmacophores we were…”
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Efficient Biomimetic Hydroxylation Catalysis with a Bis(pyrazolyl)imidazolylmethane Copper Peroxide Complex
Published in Chemistry : a European journal (01-12-2015)“…Bis(pyrazolyl)methane ligands are excellent components of model complexes used to investigate the activity of the enzyme tyrosinase. Combining the N donors…”
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