Search Results - "Runnebaum, I B"

Ovarian cancer prevention by opportunistic salpingectomy is a new de facto standard in Germany by Runnebaum, I. B., Kather, A., Vorwergk, J., Cruz, J. J., Mothes, A. R., Beteta, C. R., Boer, J., Keller, M., Pölcher, M., Mustea, A., Sehouli, J.

“…Purpose The most prevalent and aggressive subtype of epithelial ovarian carcinoma (EOC), high-grade serous carcinoma (HGSC), originates in many cases from the…”
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Inverse correlation between urethral length and continence before and after native tissue pelvic floor reconstruction by Mothes, A. R., Mothes, H. K., Kather, A., Altendorf-Hofmann, A., Radosa, M. P., Radosa, J. C., Runnebaum, I. B.

“…Urethral length was evaluated retrospectively in patients with prolapse undergoing anterior native-tissue repair. Effects of age, prolapse stage, defect…”
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"Locus minoris resistentiae" and connective tissue weakness in older women: a case report and literature review on pelvic organ prolapse with inguinal bladder hernia by Esber, A, Kopera, A, Radosa, M P, Runnebaum, I B, Mothes, H K, Mothes, A R

“…Conditions such as genital prolapse and hernia are known to be related to connective tissue dysfunction. In this report on cases of the rare simultaneous…”
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Integration of the HPV16 genome does not invariably result in high levels of viral oncogene transcripts by Häfner, N, Driesch, C, Gajda, M, Jansen, L, Kirchmayr, R, Runnebaum, I B, Dürst, M

“…Virus integration into the host genome is a characteristic step during cervical carcinogenesis. Experimental data provide evidence that integration could…”
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Liver resection in selected patients with metastatic breast cancer: a single-centre analysis and review of literature by Dittmar, Y., Altendorf-Hofmann, A., Schüle, S., Ardelt, M., Dirsch, O., Runnebaum, I. B., Settmacher, U.

“…Purpose Despite the development of modern chemotherapeutics and target-specific drugs as well as improved surgical techniques, prognosis of metastatic breast…”
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A randomized phase III adjuvant study in high-risk cervical cancer: simultaneous radiochemotherapy with cisplatin (S-RC) versus systemic paclitaxel and carboplatin followed by percutaneous radiation (PC-R): a NOGGO-AGO Intergroup Study by Sehouli, J., Runnebaum, I.B., Fotopoulou, C., Blohmer, U., Belau, A., Leber, H., Hanker, L.C., Hartmann, W., Richter, R., Keyver-Paik, M.D., Oberhoff, C., Heinrich, G., du Bois, A., Olbrich, C., Simon, E., Friese, K., Kimmig, R., Boehmer, D., Lichtenegger, W., Kuemmel, S.

“…Simultaneous adjuvant platinum-based radiochemotherapy in high-risk cervical cancer (CC) is an established treatment strategy. Sequential paclitaxel (Taxol)…”
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Efficacy control of therapy using circulating epithelial tumor cells (CETC) as “Liquid Biopsy”: trastuzumab in HER2/neu-positive breast carcinoma by Pachmann, Katharina, Camara, O., Kroll, T., Gajda, M., Gellner, A. K., Wotschadlo, J., Runnebaum, I. B.

“…Purpose The majority of targeted personalized cancer therapies are effective only in part of the patients, and most of these drugs are excessively expensive…”
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Ablative dual-phase Erbium:YAG laser treatment of atrophy-related vaginal symptoms in post-menopausal breast cancer survivors omitting hormonal treatment by Mothes, A. R., Runnebaum, M., Runnebaum, I. B.

“…Purpose First evaluation of dual-phase vaginal Er:YAG laser to omit hormonal treatment for atrophy-related symptoms in post-menopausal breast cancer survivors…”
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Laparoscopic lymphocele fenestration in gynaecological cancer patients after retroperitoneal lymph node dissection as a first‐line treatment option by Radosa, MP, Diebolder, H, Camara, O, Mothes, A, Anschuetz, J, Runnebaum, IB

“…Objective To evaluate laparoscopic lymphocele fenestration (LLF) as a first‐line treatment in gynaecological cancer patients with a history of retroperitoneal…”
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CAR is a cell-cell adhesion protein in human cancer cells and is expressionally modulated by dexamethasone, TNFα, and TGFβ by BRÜNING, A, RUNNEBAUM, I. B

“…The coxsackie adenovirus receptor (CAR) has become of interest for gene therapy due to its crucial function in adenoviral cell entry. In clinical trials with…”
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Sentinel nodes in vulvar cancer: Long-term follow-up of the GROningen INternational Study on Sentinel nodes in Vulvar cancer (GROINSS-V) I by te Grootenhuis, N.C, van der Zee, A.G.J, van Doorn, H.C, van der Velden, J, Vergote, I, Zanagnolo, V, Baldwin, P.J, Gaarenstroom, K.N, van Dorst, E.B, Trum, J.W, Slangen, B.F.M, Runnebaum, I.B, Tamussino, K, Hermans, R.H, Provencher, D.M, de Bock, G.H, de Hullu, J.A, Oonk, M.H.M

“…Abstract Objective In 2008 GROINSS-V-I, the largest validation trial on the sentinel node (SN) procedure in vulvar cancer, showed that application of the…”
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Treatment of endometriosis of uterosacral ligament and rectum through the vagina: description of a modified technique by Camara, O., Herrmann, J., Egbe, A., Kavallaris, A., Diebolder, H., Gajda, M., Runnebaum, I.B.

“…BACKGROUND Endometriosis is common in women of childbearing age, whereas involvement of the rectosigmoid requiring resection is rare. Laparoscopy has become a…”
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Surgical Management of Multiple Bilateral Fibroadenoma of the Breast: The Ribeiro Technique Modified by Rezai by CAMARA, O, EGBE, A, KOCH, I, HERRMANN, J, GAJDA, M, BALTZER, P, RUNNEBAUM, I. B

“…Background: Fibroadenomas are hyperplasia arising from the terminal ductulo-lobular unit and adjacent tissue of the breast. As single fibroadenoma, even giant…”
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Autoimmunity against p53 predicts invasive cancer with poor survival in patients with an ovarian mass by VOGL, F. D, FREY, M, KREIENBERG, R, RUNNEBAUM, I. B

“…Serum autoantibodies against the p53 protein (p53 AAb) were analysed with a newly developed enzyme-linked immunosorbent assay (ELISA) based on highly purified…”
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Mutations in p53 as Potential Molecular Markers for Human Breast Cancer by Runnebaum, Ingo B., Nagarajan, Mahalakshmi, Bowman, Marianne, Soto, Darya, Sukumar, Saraswati

“…Based on the high incidence of loss of heterozygosity for loci on chromosome 17p in the vicinity of the p53 locus in human breast tumors, we investigated the…”
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Prophylactic bilateral salpingectomy (PBS) to reduce ovarian cancer risk incorporated in standard premenopausal hysterectomy: complications and re-operation rate by Vorwergk, J., Radosa, M. P., Nicolaus, K., Baus, N., Jimenez Cruz, J., Rengsberger, M., Gajda, M., Diebolder, H., Runnebaum, I. B.

“…Purpose Hysterectomy for benign conditions can be combined with bilateral salpingectomy to prevent re-intervention for malignant or benign fallopian tube…”
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Risk index for pelvic organ prolapse based on established individual risk factors by Mothes, A. R., Radosa, M. P., Altendorf-Hofmann, A., Runnebaum, I. B.

“…Purpose To identify known risk factors for pelvic organ prolapse (POP) in a hospital cohort and to develop a prolapse risk index (PRI). Methods Risk factors…”
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Long-term risk of fibroid recurrence after laparoscopic myomectomy by Radosa, M.P, Owsianowski, Z, Mothes, A, Weisheit, A, Vorwergk, J, Asskaryar, F.A, Camara, O, Bernardi, T.S, Runnebaum, I.B

“…Abstract Objective The use of laparoscopic myomectomy as a surgical treatment for uterine leiomyoma is associated with low intraoperative morbidity and short…”
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Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations by WANG-GOHRKE, S, WEIKEL, W, STICKELER, E, KIEBACK, D. G, KREIENBERG, R, WEBER, B, NAROD, S. A, RUNNEBAUM, I. B, RISCH, H, VESPRINI, D, ABRAHAMSON, J, LERMAN, C, GODWIN, A, MOSLEHI, R, OLIPADE, O, BRUNET, J.-S

“…Two biallelic polymorphisms in introns 3 and 6 of the p53 gene were analysed for a possible risk-modifying effect for ovarian cancer. Germline DNA was…”
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Progesterone receptor gene polymorphism is associated with decreased risk for breast cancer by age 50 by WANG-GOHRKE, S, CHANG-CLAUDE, J, BECHER, H, KIEBACK, D. G, RUNNEBAUM, I. B

“…In a population-based case-control study for breast cancer before the age of 51 years, 554 cases and 559 age-matched controls were genotyped for the…”
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