Search Results - "Rune, I"

Inhibition of sorbitol dehydrogenase by nucleosides and nucleotides by Lindstad, Rune I., Teigen, Knut, Skjeldal, Lars

“…•Sheep liver sorbitol dehydrogenase is inhibited by nucleosides and corresponding nucleoside phosphates.•The reversible inhibition patterns reflect formation…”
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Quality of life is impaired in patients with peristomal bulging of a sigmoid colostomy by Kald, Anders, Juul, Kristian N., Hjortsvang, Henrik, Sjödahl, Rune I.

“…Objective. Peristomal bulging caused by hernia or prolapse is common in patients with a sigmoidostomy. It is not known whether and to what extent peristomal…”
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Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease by Rune, I., Hess, C., Jensen, H. E., Kvist, Peter H., Ougaard, M. K. E., Søndergaard, Henrik

“…Using the nonaccelerated murine nephrotoxic nephritis (NTN) as a model of chronic kidney disease (CKD) could provide an easily inducible model that enables a…”
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The clinical outcome of LMNA missense mutations can be associated with the amount of mutated protein in the nuclear envelope by Al‐Saaidi, Rasha A., Rasmussen, Torsten B., Birkler, Rune I.D., Palmfeldt, Johan, Beqqali, Abdelaziz, Pinto, Yigal M., Nissen, Peter H., Baandrup, Ulrik, Mølgaard, Henning, Hey, Thomas M., Eiskjær, Hans, Bross, Peter, Mogensen, Jens

“…Aims Lamin A/C mutations are generally believed to be associated with a severe prognosis. The aim of this study was to investigate disease expression in three…”
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Effects of a Mutation in the HSPE1 Gene Encoding the Mitochondrial Co-chaperonin HSP10 and Its Potential Association with a Neurological and Developmental Disorder by Bie, Anne S, Fernandez-Guerra, Paula, Birkler, Rune I D, Nisemblat, Shahar, Pelnena, Dita, Lu, Xinping, Deignan, Joshua L, Lee, Hane, Dorrani, Naghmeh, Corydon, Thomas J, Palmfeldt, Johan, Bivina, Liga, Azem, Abdussalam, Herman, Kristin, Bross, Peter

“…We here report molecular investigations of a missense mutation in the gene encoding the HSP10 subunit of the HSP60/ HSP10 chaperonin complex that assists…”
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Ultrasonographic findings in patients with peristomal bulging by Sjödahl, Rune I., Thorelius, Lars, Hallböök, Olof J.

“…Abstract Aim. The aim of this study was to obtain a classification of peristomal bulging based on findings at ultrasonography in patients with a sigmoid…”
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Evaluation of the moderately obese apoe gene knockout rat as a new model for impaired glucose tolerance and atherosclerosis by Rune, I, Rolin, B, Lykkesfeldt, J, Chistoffersen, B, Kirk, R.K, Hansen, A.K

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Changing dietary content of gluten–and potentially the gut microbiota, did not result in increased atherosclerosis in the apoe-/-mouse by Rune, I, Rolin, B, Lykkesfeldt, J, Chistoffersen, B, Kirk, R.K, Hansen, A.K

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Ampicillin-Improved Glucose Tolerance in Diet-Induced Obese C57BL/6NTac Mice Is Age Dependent by Rune, I., Hansen, C. H. F., Ellekilde, M., Nielsen, D. S., Skovgaard, K., Rolin, B. C., Lykkesfeldt, J., Josefsen, K., Tranberg, B., Kihl, P., Hansen, A. K.

“…Ampicillin has been shown to improve glucose tolerance in mice. We hypothesized that this effect is present only if treatment is initiated prior to weaning and…”
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Adverse events identified by Global Trigger Tool in 245 patients with colon cancer in a well-defined population by Sjödahl, Rune I., Heedman, Per-Anders I., Henriks, Göran K.B., Starkhammar, Hans F.

“…Purpose: To report the rate, the type and the preventability of adverse events in patients with colon cancer. Materials and methods: In this retrospective…”
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Early predictors of glucocorticosteroid treatment failure in severe and moderately severe attacks of ulcerative colitis by Lindgren, S C, Flood, L M, Kilander, A F, Löfberg, R, Persson, T B, Sjödahl, R I

“…To analyse the ability of simple clinical and biochemical parameters to predict glucocorticosteroid (GCS) treatment failure in patients with acute attacks of…”
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Selected reaction monitoring as an effective method for reliable quantification of disease‐associated proteins in maple syrup urine disease by Fernández‐Guerra, Paula, Birkler, Rune I. D., Merinero, Begoña, Ugarte, Magdalena, Gregersen, Niels, Rodríguez‐Pombo, Pilar, Bross, Peter, Palmfeldt, Johan

“…Selected reaction monitoring (SRM) mass spectrometry can quantitatively measure proteins by specific targeting of peptide sequences, and allows the…”
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Pancreatic Trypsin Activates Human Promatrix Metalloproteinase-2 by Lindstad, Rune I., Sylte, Ingebrigt, Mikalsen, Svein-Ole, Seglen, Per O., Berg, Eli, Winberg, Jan-Olof

“…In contrast to the prevalent view in the literature hitherto, the present study shows that pancreatic trypsin can activate human promatrix metalloproteinase-2…”
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S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells by Mathisen, Berit, Lindstad, Rune I, Hansen, Janne, El-Gewely, Sara Ann, Maelandsmo, Gunhild M, Hovig, Eivind, Fodstad, Oystein, Loennechen, Thrina, Winberg, Jan-Olof

“…To study the role of the metastasis associated protein S100A4, an osteosarcoma cell line (OHS) with a high level of this protein was transfected with a vector…”
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Colchicine induces membrane-associated activation of matrix metalloproteinase-2 in osteosarcoma cells in an S100A4-independent manner by Loennechen, Thrina, Mathisen, Berit, Hansen, Janne, Lindstad, Rune I, El-Gewely, Sara Ann, Andersen, Kristin, Mælandsmo, Gunhild M, Winberg, Jan-Olof

“…Like the metastasis-associated protein S100A4, matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are important in physiological and…”
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The catalytic triad in Drosophila alcohol dehydrogenase: pH, temperature and molecular modelling studies by Winberg, Jan-Olof, Brendskag, Michelle Kaaber, Sylte, Ingebrigt, Lindstad, Rune I, McKinley-McKee, John S

“…Drosophila alcohol dehydrogenase belongs to the short chain dehydrogenase/reductase (SDR) family which lack metal ions in their active site. In this family, it…”
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Substrate specificity of sheep liver sorbitol dehydrogenase by Lindstad, R I, Köll, P, McKinley-McKee, J S

“…The substrate specificity of sheep liver sorbitol dehydrogenase has been studied by steady-state kinetics over the range pH 7-10. Sorbitol dehydrogenase…”
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Fumarate Is Cardioprotective via Activation of the Nrf2 Antioxidant Pathway by Ashrafian, Houman, Czibik, Gabor, Bellahcene, Mohamed, Aksentijević, Dunja, Smith, Anthony C., Mitchell, Sarah J., Dodd, Michael S., Kirwan, Jennifer, Byrne, Jonathan J., Ludwig, Christian, Isackson, Henrik, Yavari, Arash, Støttrup, Nicolaj B., Contractor, Hussain, Cahill, Thomas J., Sahgal, Natasha, Ball, Daniel R., Birkler, Rune I.D., Hargreaves, Iain, Tennant, Daniel A., Land, John, Lygate, Craig A., Johannsen, Mogens, Kharbanda, Rajesh K., Neubauer, Stefan, Redwood, Charles, de Cabo, Rafael, Ahmet, Ismayil, Talan, Mark, Günther, Ulrich L., Robinson, Alan J., Viant, Mark R., Pollard, Patrick J., Tyler, Damian J., Watkins, Hugh

“…The citric acid cycle (CAC) metabolite fumarate has been proposed to be cardioprotective; however, its mechanisms of action remain to be determined. To augment…”
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Methylglyoxal and the polyol pathway by Lindstad, Rune I., McKinley-McKee, John S.

“…Methylglyoxal, 1,2‐propanediol and glycerol are shown to be substrates for sheep liver sorbitol dehydrogenase. With 1,2‐propanediol the enzymecatalyzed…”
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Anal and rectal cancer in Crohn's disease by Sjödahl, R. I., Myrelid, P., Söderholm, J. D.

“…Several epidemiological studies have been published regarding the risk of Crohn's disease‐ associated colorectal cancer. The findings are, however,…”
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